(e,e,e,e)-squalene

(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (e,e,e,e)-squalene?

(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene

MeSH term MeSH ID Detail
Persian Gulf Syndrome D018923 1 associated lipids
Hemorrhagic Septicemia, Viral D031941 1 associated lipids
Steatorrhea D045602 2 associated lipids
Fasciitis D005208 2 associated lipids
Ossification, Heterotopic D009999 2 associated lipids
Pneumonia, Lipid D011017 2 associated lipids
Gallbladder Diseases D005705 3 associated lipids
Exostoses, Multiple Hereditary D005097 3 associated lipids
Simian Acquired Immunodeficiency Syndrome D016097 4 associated lipids
Hyperlipoproteinemia Type III D006952 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with (e,e,e,e)-squalene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (e,e,e,e)-squalene?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (e,e,e,e)-squalene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (e,e,e,e)-squalene

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Authors Title Published Journal PubMed Link
Corey EJ et al. 2,3-iminosqualene, a potent inhibitor of the enzymic cyclization of 2,3-oxidosqualene to sterols. 1967 J. Am. Chem. Soc. pmid:6043808
Corey EJ and Gross SK Formation of sterols by the action of 2,3-oxidosqualene-sterol cyclase on the factitious substrates 2,3:22,23-dioxidosqualene and 2,3-oxido-22,23-dihydrosqualene. 1967 J. Am. Chem. Soc. pmid:6046552
Wepierre J [Impermeability of mouse skin to tritiated perhydrosqualene]. 1967 Jul-Aug Ann Pharm Fr pmid:5618585
Young TE and Maggs RJ The use of a moving wire detector system for the study of liquid chromatographic columns. 1967 May-Jun Anal. Chim. Acta pmid:6045413
Markelova VF and Levachev MM [Inclusion of C14-acetate in cholesterol and tissue squalene of rats in choline-protein deficiency]. 1967 Nov-Dec Vopr Pitan pmid:5610866
Rees HH et al. The biosynthesis of beta-amyrin. Mechanism of squalene cyclization. 1968 Biochem. J. pmid:5639923
Rees HH et al. Cyclization of 2,3-oxidosqualene to cycloartenol in a cell-free system from higher plants. 1968 Tetrahedron Lett. pmid:5640097
Scharf SS and Simpson KL Attempts to detect lycopersene formation in yeast. 1968 Biochem. J. pmid:5753091
Merdinger E et al. Composition of lipids in extracts of Pullularia pullulans. 1968 Can. J. Microbiol. pmid:5693067
Caspi E et al. The biosynthesis of tetrahymanol in vitro. 1968 Biochem. J. pmid:5696872