| MeSH term | MeSH ID | Detail |
|---|---|---|
| Acne Vulgaris | D000152 | 35 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Alopecia Areata | D000506 | 6 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Arthritis, Experimental | D001169 | 24 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Brain Diseases | D001927 | 27 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
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|---|---|---|---|---|
| Zambonin CG et al. | Laser desorption/ionization time-of-flight mass spectrometry of squalene in oil samples. | 2006 | Rapid Commun. Mass Spectrom. | pmid:16345138 |
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| Morimoto Y et al. | Two-directional synthesis and stereochemical assignment toward a C2 symmetric oxasqualenoid (+)-intricatetraol. | 2006 | Org. Biomol. Chem. | pmid:17036107 |
| Atmar RL et al. | Safety and immunogenicity of nonadjuvanted and MF59-adjuvanted influenza A/H9N2 vaccine preparations. | 2006 | Clin. Infect. Dis. | pmid:17029131 |
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| Peltola P et al. | Visceral obesity is associated with high levels of serum squalene. | 2006 | Obesity (Silver Spring) | pmid:16899796 |
| Stephenson I et al. | Phase I evaluation of intranasal trivalent inactivated influenza vaccine with nontoxigenic Escherichia coli enterotoxin and novel biovector as mucosal adjuvants, using adult volunteers. | 2006 | J. Virol. | pmid:16641287 |
| Suzuki M et al. | Lanosterol synthase in dicotyledonous plants. | 2006 | Plant Cell Physiol. | pmid:16531458 |
| Senthilkumar S et al. | Attenuation of cyclophosphamide induced toxicity by squalene in experimental rats. | 2006 | Chem. Biol. Interact. | pmid:16554041 |
| Köhler SP et al. | Molecular dynamics study to identify the reactive sites of a liquid squalane surface. | 2006 | J Phys Chem B | pmid:16800468 |
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| Spanggord RJ et al. | Enhancement of an analytical method for the determination of squalene in anthrax vaccine adsorbed formulations. | 2006 | J Pharm Biomed Anal | pmid:16762524 |
| Ottaviani M et al. | Peroxidated squalene induces the production of inflammatory mediators in HaCaT keratinocytes: a possible role in acne vulgaris. | 2006 | J. Invest. Dermatol. | pmid:16778793 |
| Hallikainen M et al. | Postprandial behavior of plasma squalene and non-cholesterol sterols in men with varying cholesterol absorption. | 2006 | Clin. Chim. Acta | pmid:16814761 |
| Zadák Z et al. | Polyunsaturated fatty acids, phytosterols and cholesterol metabolism in the Mediterranean diet. | 2006 | Acta Medica (Hradec Kralove) | pmid:16696439 |
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| Farvin KH et al. | Cardioprotective effect of squalene on lipid profile in isoprenaline-induced myocardial infarction in rats. | 2006 | J Med Food | pmid:17201641 |
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| Germann M et al. | Characterizing sterol defect suppressors uncovers a novel transcriptional signaling pathway regulating zymosterol biosynthesis. | 2005 | J. Biol. Chem. | pmid:16120615 |
| Lau HL et al. | Simultaneous quantification of free fatty acids, free sterols, squalene, and acylglycerol molecular species in palm oil by high-temperature gas chromatography--flame ionization detection. | 2005 | Lipids | pmid:16094863 |
| Oliaro-Bosso S et al. | Analogs of squalene and oxidosqualene inhibit oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae. | 2005 | Lipids | pmid:16477810 |
| Archer NE et al. | Changes in the lipid composition of latent fingerprint residue with time after deposition on a surface. | 2005 | Forensic Sci. Int. | pmid:16182971 |
| Lee KH et al. | Squalene aspiration pneumonia in children: radiographic and CT findings as the first clue to diagnosis. | 2005 | Pediatr Radiol | pmid:15806404 |
| Aguilera Y et al. | The protective role of squalene in alcohol damage in the chick embryo retina. | 2005 | Exp. Eye Res. | pmid:15781281 |