(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kulakova SN et al. | [Amaranths oil: peculiarities of chemical composition and influence on lipid metabolism by rats]. | 2006 | Vopr Pitan | pmid:16862953 |
PokrovskiÄ AA et al. | [Method of isolating, identifying and quantitatively determining alkanes, cycloalkanes, monocyclic arenes and squalene in animal organs and tissues]. | 1978 Sep-Oct | Vopr Pitan | pmid:716335 |
Markelova VF and Levachev MM | [Inclusion of C14-acetate in cholesterol and tissue squalene of rats in choline-protein deficiency]. | 1967 Nov-Dec | Vopr Pitan | pmid:5610866 |
Gonor KV et al. | [The influence of a diet with including amaranth oil on antioxidant and immune status in patients with ischemic heart disease and hyperlipoproteidemia]. | 2006 | Vopr Pitan | pmid:17313043 |
Palamarchuk VI et al. | [Content of squalene and sterols in tissues of the hemopoietic system in normal rats and in experimental leukemia]. | 1983 May-Jun | Vopr. Med. Khim. | pmid:6880121 |
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Lynen F | [The biochemical basis of the biosynthesis of cholesterol and fatty acids]. | 1966 | Wien. Klin. Wochenschr. | pmid:4296920 |
Bakalar B et al. | Changes in cholesterol and its precursors during the first days after major trauma. | 2003 | Wien. Klin. Wochenschr. | pmid:14743581 |
Global Advisory Committee on Vaccine Safety, 6-7 June 2006. | 2006 | Wkly. Epidemiol. Rec. | pmid:16841398 | |
Richter E et al. | Stimulation of the faecal excretion of 2,4,5,2',4',5'-hexachlorobiphenyl in rats by squalane. | 1983 | Xenobiotica | pmid:6415933 |
Hu JJ et al. | [Antibody production and its neutralization of Abeta42's cytoxicity in BALB/c mice induced by Abeta42 and its subunit vaccines]. | 2004 | Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi | pmid:15191720 |
Ikekawa T et al. | [Studies on antitumor activity of squalene and its related compounds]. | 1986 | Yakugaku Zasshi | pmid:3772729 |
Abe I | [Engineering of squalene cyclizing enzymes]. | 2008 | Yakugaku Zasshi | pmid:18670176 |
Tsai TF | MF59 adjuvanted seasonal and pandemic influenza vaccines. | 2011 | Yakugaku Zasshi | pmid:22129867 |
Zhang Y et al. | [Chemical constituents from the mangrove plant Ceriops tagal]. | 2005 | Yao Xue Xue Bao | pmid:16408813 |
Sondergaard E et al. | Alimentary production of gallstones in hamsters. 28. Influence of isomerized squalene on gallstone production. | 1974 | Z Ernahrungswiss | pmid:4450595 |
Dam H et al. | Alimentary production of gallstones in hamsters. 27. Influence of supplementation of the gallstone producing diet with squalene, cholesterol, certain other sterols, fish oil fatty acid ethyl esters, and modification of the basal diet on gallstone production and levels of cholesterol in serum and liver. | 1974 | Z Ernahrungswiss | pmid:4615449 |