(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Amdur BH et al. | Presence of squalene in gram-positive bacteria. | 1978 | J. Bacteriol. | pmid:670148 |
| Gavey KL and Scallen TJ | Studies on the conversion of enzymatically generated, microsome-bound squalene to sterol. | 1978 | J. Biol. Chem. | pmid:670211 |
| Wysocki SJ et al. | Simultaneous assessment of fetal lung maturity and sebaceous gland function by gas chromatography. | 1984 | Clin. Chim. Acta | pmid:6705230 |
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| Rohmer M et al. | Non-specific lanosterol and hopanoid biosynthesis be a cell-free system from the bacterium Methylococcus capsulatus. | 1980 | Eur. J. Biochem. | pmid:6780348 |
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| Kling D and Gamble W | Cholesterol biosynthesis in polychlorinated biphenyl-treated rats. | 1982 | Environ. Res. | pmid:6802634 |
| Schroepfer GJ | Sterol biosynthesis. | 1982 | Annu. Rev. Biochem. | pmid:6810750 |
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| Kudchodkar BJ et al. | Mechanisms of hypolipidemic action of nicotinic acid. | 1978 | Clin. Pharmacol. Ther. | pmid:688728 |
| Tilvis R and Miettinen TA | Squalene, methyl sterol, and cholesterol levels in human organs. Postmortem analysis of their distributions. | 1980 | Arch. Pathol. Lab. Med. | pmid:6892520 |
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| Tornabene TG | Non-aerated cultivation of Halobacterium cutirubrum and its effect on cellular squalenes. | 1978 | J. Mol. Evol. | pmid:691076 |
| Tornabene TG et al. | Phytanyl-glycerol ethers and squalenes in the archaebacterium Methanobacterium thermoautotrophicum. | 1978 | J. Mol. Evol. | pmid:691077 |
| Moroyama T | [Sterol metabolism of cultured skin tissue of chick embryo and the effect of anticholesterolemic drugs and chemical carcinogens on it (author's transl)]. | 1981 | Hiroshima Daigaku Shigaku Zasshi | pmid:6953141 |
| Jenkins DT et al. | Amniotic fluid squalene: a useful test in prolonged pregnancy. | 1982 | Aust N Z J Obstet Gynaecol | pmid:6959611 |
| Yoshino K and Matsuo I | [Squalene peroxide formation by UVA irradiation with or without 8-MOP (author's transl)]. | 1981 | Nihon Hifuka Gakkai Zasshi | pmid:6971356 |
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| White SH | Formation of "solvent-free" black lipid bilayer membranes from glyceryl monooleate dispersed in squalene. | 1978 | Biophys. J. | pmid:698340 |
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| Masuda A et al. | Potentiation of antifungal effect of amphotericin B by squalene, an intermediate for sterol biosynthesis. | 1982 | J. Antibiot. | pmid:7042672 |
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| Torinuki W et al. | Effect of beta-carotene on ultraweak chemiluminescence of UVB-irradiated squalene. | 1982 | Tohoku J. Exp. Med. | pmid:7101278 |
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| Morin RJ et al. | Effect of age and cholestyramine feeding on rat liver 3-hydroxy-3-methyl glutaryl CoA reductase, sterol carrier protein 1 and sterol carrier protein 2 activities. | 1982 | Lipids | pmid:7121212 |
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| Tilvis RS and Miettinen TA | Fate of intravenously administered squalene in the rat. | 1982 | Biochim. Biophys. Acta | pmid:7126611 |