(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Scallen TJ et al. | Enzymatic conversion of squalene to cholesterol by an acetone powder of rat liver microsomes. | 1968 | Biochem. Biophys. Res. Commun. | pmid:5653642 |
Dada OA et al. | Biosynthesis of phytoquinones. Stereospecific biosynthesis of the polyprenyl side chains of terpenoid quinones and chromanols in maize shoots. | 1968 | Eur. J. Biochem. | pmid:5653765 |
Wepierre J et al. | Percutaneous absorption and removal by the body fluids of 14C ethyl alcohol, 3H perhydrosqualene and 14C p-cymene. | 1968 | Eur. J. Pharmacol. | pmid:5654669 |
Gianelly AA and Terner C | Inhibition of cholesterol biosynthesis by dehydroepiandrosterone in lactating mammary gland. | 1968 | Endocrinology | pmid:4177463 |
Locke DC | Chromatographic study of solutions of hydrocarbons in acetonitrile. | 1968 | J. Chromatogr. | pmid:5656425 |
Voogt PA | Investigations of the capacity of synthesizing 3 beta-sterols in Mollusca. 3. The biosynthesis of 3 beta-sterols in some archeogastropods. | 1968 | Arch. Int. Physiol. Biochim. | pmid:4178041 |
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Giddings JC et al. | High pressure gas chromatography of nonvolatile species. Compressed gas is used to cause migration of intractable solutes. | 1968 | Science | pmid:5675186 |
De Souza NJ and Nes WR | Sterols: isolation from a blue-green alga. | 1968 | Science | pmid:5677529 |
White HB et al. | The occurrence of squalene in kipid of fowlpox virus. | 1968 | J. Biol. Chem. | pmid:5684008 |
Godtfredsen WO et al. | Biosynthesis of fusidic acid from squalene 2,3-oxide. | 1968 | J. Am. Chem. Soc. | pmid:5688690 |
Scharf SS and Simpson KL | Attempts to detect lycopersene formation in yeast. | 1968 | Biochem. J. | pmid:5753091 |
Merdinger E et al. | Composition of lipids in extracts of Pullularia pullulans. | 1968 | Can. J. Microbiol. | pmid:5693067 |
Caspi E et al. | The biosynthesis of tetrahymanol in vitro. | 1968 | Biochem. J. | pmid:5696872 |
Ackman RG et al. | Unusual occurrence of squalene in a fish, the eulachon Thaleichthys pacificus. | 1968 | Nature | pmid:5701840 |
Conner RL et al. | Cholesterol inhibition of pentacyclic triterpenoid biosynthesis in Tetrahymena pyriformis. | 1968 | J. Protozool. | pmid:5703082 |
Suzuki R | Specific requirements of bile salts for absorption of cholesterol from the intestine. | 1968 | Keio J Med | pmid:5715537 |
Mukherjee S and Bhose A | Studies on estrogen regulation of cholesterol biosynthesis in rat liver microsomes. | 1968 | Biochim. Biophys. Acta | pmid:5721032 |
Threlfall DR et al. | Biosynthesis of phytoquinones. Incorporation of L-[Me-14C,3H]methionine into terpenoid quinones and chromanols in maize shoots. | 1968 | Biochem. J. | pmid:5721452 |
Autrum H et al. | [Squalene in the glandular secretion of mammals]. | 1968 | Naturwissenschaften | pmid:5726004 |