(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Pimm MV et al. | Suppression of an ascitic rat hepatoma with cord factor and Nocardia cell wall skeleton in squalene emulsions. | 1980 | Eur J Cancer | pmid:7227439 |
| Sirtori CR et al. | Reduced triglyceridemia and increased high density lipoprotein cholesterol levels after treatment with acipimox, a new inhibitor of lipolysis. | 1981 Feb-Mar | Atherosclerosis | pmid:7225165 |
| Brassell SC et al. | Specific acyclic isoprenoids as biological markers of methanogenic bacteria in marine sediments. | 1981 | Nature | pmid:7219553 |
| Lindholm JS and Downing DT | Occurrence of squalene in skin surface lipids of the otter, the beaver and the kinkajou. | 1980 | Lipids | pmid:7219074 |
| Yarkoni E et al. | Immunotherapy of experimental cancer with a mixture of synthetic muramyl dipeptide and trehalose dimycolate. | 1981 | Infect. Immun. | pmid:7216489 |
| Trocha PJ and Sprinson DB | Location and regulation of early enzymes of sterol biosynthesis in yeast. | 1976 | Arch. Biochem. Biophys. | pmid:7207 |
| Miettinen TA | Diurnal variation of cholesterol precursors squalene and methyl sterols in human plasma lipoproteins. | 1982 | J. Lipid Res. | pmid:7200504 |
| Albers-Jackson B et al. | Incorporation of 14C acetate into the sterols of rabbit lens in organ culture. | 1982-1983 | Curr. Eye Res. | pmid:7184713 |
| Bird S and Gower DB | Axillary 5 alpha-androst-16-en-3-one, cholesterol and squalene in men; preliminary evidence for 5 alpha-androst-16-en-3-one being a product of bacterial action. | 1982 | J. Steroid Biochem. | pmid:7176644 |
| PokrovskiÄ AA et al. | [Method of isolating, identifying and quantitatively determining alkanes, cycloalkanes, monocyclic arenes and squalene in animal organs and tissues]. | 1978 Sep-Oct | Vopr Pitan | pmid:716335 |
| Bell FP and Hubert EV | Stimulation of hepatic squalene and triglyceride synthesis by dimethylsulfoxide, in vitro. | 1982 | Lipids | pmid:7162368 |
| Morin RJ and Srikantaiah MV | Inhibition of rat liver sterol formation by isoprenoid and conjugated ene compounds. | 1982 | Pharmacol Res Commun | pmid:7156175 |
| Olugbade TA et al. | Chemical constituents of Cnestis ferruginea DC. I. Petroleum ether fraction. | 1982 | J Ethnopharmacol | pmid:7154704 |
| Maugh TH | Completing the puzzle of steroid synthesis, a mystery in the biological synthesis of steroids is solved, providing a new approach to chemical synthesis of the compounds. | 1982 | Science | pmid:7146911 |
| Morozova RP et al. | [Separation of lipid extract from animal blood and tissues and isolation of squalene and sterols from it]. | 1982 Jul-Aug | Ukr. Biokhim. Zh. | pmid:7135500 |
| Emmons GT et al. | Effects of 20,25-diazacholesterol on cholesterol synthesis in cultured chick muscle cells: a radiogas chromatographic and mass spectrometric study of the post-squalene sector. | 1982 | Biomed. Mass Spectrom. | pmid:7126761 |
| Tilvis RS and Miettinen TA | Fate of intravenously administered squalene in the rat. | 1982 | Biochim. Biophys. Acta | pmid:7126611 |
| Dillard CJ et al. | Lipid peroxidation during chronic inflammation induced in rats by Freund's adjuvant: effect of vitamin E as measured by expired pentane. | 1982 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:7122999 |
| Saudek CD et al. | Plasma squalene: lipoprotein distribution and kinetic analysis. | 1978 | J. Lipid Res. | pmid:712242 |
| Morin RJ et al. | Effect of age and cholestyramine feeding on rat liver 3-hydroxy-3-methyl glutaryl CoA reductase, sterol carrier protein 1 and sterol carrier protein 2 activities. | 1982 | Lipids | pmid:7121212 |
| Tilvis R et al. | Metabolism of squalene in human fat cells. Demonstration of a two-pool system. | 1982 | J. Biol. Chem. | pmid:7107606 |
| Tiffany JM | Individual variations in human meibomian lipid composition. | 1978 | Exp. Eye Res. | pmid:710541 |
| Torinuki W et al. | Effect of beta-carotene on ultraweak chemiluminescence of UVB-irradiated squalene. | 1982 | Tohoku J. Exp. Med. | pmid:7101278 |
| Richter E and Schäfer SG | The effect of squalane on the absorption of dietary cholesterol by the rat. | 1982 | Res Exp Med (Berl) | pmid:7100640 |
| Richter E and Schäfer SG | Effect of squalane on hexachlorobenzene (HCB) concentrations in tissues of mice. | 1982 | J Environ Sci Health B | pmid:7096897 |
| Messeri G et al. | Amniotic fluid squalene and gestational age. | 1982 | Clin. Chem. | pmid:7094305 |
| Richter E et al. | Effects of dietary paraffin, squalane and sucrose polyester on residue disposition and elimination of hexachlorobenzene in rats. | 1982 | Chem. Biol. Interact. | pmid:7083398 |
| Tilvis RS et al. | Lipid composition of bile and gallbladder mucosa in patients with acalculous cholesterolosis. | 1982 | Gastroenterology | pmid:7060883 |
| Pratt HP | Preimplantation mouse embryos synthesize membrane sterols. | 1982 | Dev. Biol. | pmid:7054002 |
| Bach D and Miller IR | Glyceryl monooleate black lipid membranes obtained from squalene solutions. | 1980 | Biophys. J. | pmid:7053057 |
| Takatsuji H et al. | Formation of dehydrosqualene catalyzed by squalene synthetase in Saccharomyces cerevisiae. | 1982 | J. Biochem. | pmid:7042703 |
| Masuda A et al. | Potentiation of antifungal effect of amphotericin B by squalene, an intermediate for sterol biosynthesis. | 1982 | J. Antibiot. | pmid:7042672 |
| Schroepfer GJ | Sterol biosynthesis. | 1981 | Annu. Rev. Biochem. | pmid:7023367 |
| Yarkoni E and Rapp HJ | Influence of type of oil and surfactant concentration on the efficacy of emulsified Mycobacterium bovis BCG cell walls to induce tumor regression in guinea pigs. | 1980 | Infect. Immun. | pmid:6995325 |
| White SH | Formation of "solvent-free" black lipid bilayer membranes from glyceryl monooleate dispersed in squalene. | 1978 | Biophys. J. | pmid:698340 |
| Torinuki W et al. | [Emission spectral analysis of ultraweak chemiluminescence from linolenic acid and squalene peroxides (author's transl)]. | 1982 | Nihon Hifuka Gakkai Zasshi | pmid:6978954 |
| Yoshino K and Matsuo I | [Squalene peroxide formation by UVA irradiation with or without 8-MOP (author's transl)]. | 1981 | Nihon Hifuka Gakkai Zasshi | pmid:6971356 |
| Jenkins DT et al. | Amniotic fluid squalene: a useful test in prolonged pregnancy. | 1982 | Aust N Z J Obstet Gynaecol | pmid:6959611 |
| Moroyama T | [Sterol metabolism of cultured skin tissue of chick embryo and the effect of anticholesterolemic drugs and chemical carcinogens on it (author's transl)]. | 1981 | Hiroshima Daigaku Shigaku Zasshi | pmid:6953141 |
| Tornabene TG et al. | Phytanyl-glycerol ethers and squalenes in the archaebacterium Methanobacterium thermoautotrophicum. | 1978 | J. Mol. Evol. | pmid:691077 |
| Tornabene TG | Non-aerated cultivation of Halobacterium cutirubrum and its effect on cellular squalenes. | 1978 | J. Mol. Evol. | pmid:691076 |
| Lapointe JY and Laprade R | Kinetics of carrier-mediated ion transport in two new types of solvent-free lipid bilayers. | 1982 | Biophys. J. | pmid:6896832 |
| Tilvis R and Miettinen TA | Squalene, methyl sterol, and cholesterol levels in human organs. Postmortem analysis of their distributions. | 1980 | Arch. Pathol. Lab. Med. | pmid:6892520 |
| Kudchodkar BJ et al. | Mechanisms of hypolipidemic action of nicotinic acid. | 1978 | Clin. Pharmacol. Ther. | pmid:688728 |
| Palamarchuk VI et al. | [Content of squalene and sterols in tissues of the hemopoietic system in normal rats and in experimental leukemia]. | 1983 May-Jun | Vopr. Med. Khim. | pmid:6880121 |
| Hérodin F and Dormont D | [Comparative kinetics of spleen cell-mediated antibody-dependent cytotoxic activity in mice treated with BCG or Mycobacterium smegmatis]. | 1983 Mar-Apr | Ann. Immunol. (Paris) | pmid:6870194 |
| Ohkuma T et al. | Intensification of host's immunity by squalene in sarcoma 180 bearing ICR mice. | 1983 | J. Pharmacobio-dyn. | pmid:6864440 |
| Tanio Y et al. | Regression of line-10 hepatocarcinoma with synthetic quinonyl muramyl dipeptide in strain-2 guinea pigs. | 1983 | Gan | pmid:6862142 |
| Tilvis RS and Miettinen TA | Absorption and metabolic fate of dietary 3H-squalene in the rat. | 1983 | Lipids | pmid:6855483 |
| Fuks-Holmberg D and Bloch K | Intermembrane transfer of squalene promoted by supernatant protein factor. | 1983 | J. Lipid Res. | pmid:6854149 |