(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Bibikova MV and Bondareva NS | [Drugs of microbial origin for treatment of atherosclerosis]. | 1998 | Antibiot. Khimioter. | pmid:9777104 |
Strauss JS et al. | Skin lipids and acne. | 1975 | Annu. Rev. Med. | pmid:125065 |
Schroepfer GJ | Sterol biosynthesis. | 1981 | Annu. Rev. Biochem. | pmid:7023367 |
Schroepfer GJ | Sterol biosynthesis. | 1982 | Annu. Rev. Biochem. | pmid:6810750 |
Ruzicka L | In the borderland between bioorganic chemistry and biochemistry. | 1973 | Annu. Rev. Biochem. | pmid:4600996 |
Dempsey ME | Regulation of steroid biosynthesis. | 1974 | Annu. Rev. Biochem. | pmid:4369131 |
BeytÃa ED and Porter JW | Biochemistry of polyisoprenoid biosynthesis. | 1976 | Annu. Rev. Biochem. | pmid:9026 |
Sih CJ and Whitlock HW | Biochemistry of steroids. | 1968 | Annu. Rev. Biochem. | pmid:4875723 |
Frantz ID and Schroepfer GJ | Sterol biosynthesis. | 1967 | Annu. Rev. Biochem. | pmid:18257735 |
Zhang L et al. | Proopiomelanocortin peptides and sebogenesis. | 2003 | Ann. N. Y. Acad. Sci. | pmid:12851311 |
Dempsey ME | Inhibition of lipid biosynthesis. | 1968 | Ann. N. Y. Acad. Sci. | pmid:4385358 |
Krisans SK | Cell compartmentalization of cholesterol biosynthesis. | 1996 | Ann. N. Y. Acad. Sci. | pmid:8993542 |
Newmark HL | Squalene, olive oil, and cancer risk. Review and hypothesis. | 1999 | Ann. N. Y. Acad. Sci. | pmid:10668494 |
Ekanayake-Mudiyanselage S et al. | Oral supplementation with all-Rac- and RRR-alpha-tocopherol increases vitamin E levels in human sebum after a latency period of 14-21 days. | 2004 | Ann. N. Y. Acad. Sci. | pmid:15753144 |
Langenberg AG et al. | A recombinant glycoprotein vaccine for herpes simplex virus type 2: safety and immunogenicity [corrected]. | 1995 | Ann. Intern. Med. | pmid:7755223 |
Hérodin F and Dormont D | [Comparative kinetics of spleen cell-mediated antibody-dependent cytotoxic activity in mice treated with BCG or Mycobacterium smegmatis]. | 1983 Mar-Apr | Ann. Immunol. (Paris) | pmid:6870194 |
Bartfai E et al. | [Studies on the genotoxic effects of crude liver oils from 3 species of Mediterranean sharks by means of in vitro micronucleus test using human lymphocytes]. | 2000 Sep-Oct | Ann. Biol. Clin. (Paris) | pmid:11022102 |
Cicchini T et al. | [The importance of man, mouse and rat skin surface lipid fractions on the "in vitro" penetration of "Schistosoma mansoni" cercariae (author's transl)]. | 1977 Sep-Oct | Ann Sclavo | pmid:616258 |
Montagnani S et al. | Autoimmune hemolytic anemia following MF59-adjuvanted influenza vaccine administration: a report of two cases. | 2011 | Ann Pharmacother | pmid:21189364 |
Wepierre J | [Impermeability of mouse skin to tritiated perhydrosqualene]. | 1967 Jul-Aug | Ann Pharm Fr | pmid:5618585 |