(e,e,e,e)-squalene

(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (e,e,e,e)-squalene?

(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Lung Neoplasms D008175 171 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Edema D004487 152 associated lipids
Hemolysis D006461 131 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Inflammation D007249 119 associated lipids
Weight Gain D015430 101 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Arteriosclerosis D001161 86 associated lipids
Atherosclerosis D050197 85 associated lipids
Alzheimer Disease D000544 76 associated lipids
Stomach Ulcer D013276 75 associated lipids
Leukemia D007938 74 associated lipids
Hyperlipidemias D006949 73 associated lipids
Coronary Disease D003327 70 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Neuroblastoma D009447 66 associated lipids
Pain D010146 64 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Parkinson Disease D010300 53 associated lipids
Precancerous Conditions D011230 48 associated lipids
Psoriasis D011565 47 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Leukemia P388 D007941 43 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Occupational Diseases D009784 42 associated lipids
Arthritis D001168 41 associated lipids
Nervous System Diseases D009422 37 associated lipids
Acne Vulgaris D000152 35 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Brain Diseases D001927 27 associated lipids
Niemann-Pick Diseases D009542 25 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Cholestasis D002779 23 associated lipids
Periodontitis D010518 22 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Xanthomatosis D014973 17 associated lipids
Olfaction Disorders D000857 17 associated lipids
Cholelithiasis D002769 16 associated lipids
Celiac Disease D002446 16 associated lipids
Demyelinating Diseases D003711 15 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Rosacea D012393 13 associated lipids
Keloid D007627 12 associated lipids
Otitis Media D010033 12 associated lipids
Dermatitis, Occupational D009783 12 associated lipids
Influenza, Human D007251 11 associated lipids
Hepatitis D006505 11 associated lipids
Pregnancy Complications, Infectious D011251 11 associated lipids
Scalp Dermatoses D012536 11 associated lipids
Fatigue D005221 10 associated lipids
Chondrodysplasia Punctata D002806 8 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Fibrosarcoma D005354 8 associated lipids
Chronic Disease D002908 7 associated lipids
Alopecia Areata D000506 6 associated lipids
Keratitis, Herpetic D016849 5 associated lipids
Leukemia, Hairy Cell D007943 5 associated lipids
Parasitemia D018512 5 associated lipids
Tinea Versicolor D014010 5 associated lipids
Simian Acquired Immunodeficiency Syndrome D016097 4 associated lipids
Hyperlipoproteinemia Type III D006952 4 associated lipids
Coronavirus Infections D018352 4 associated lipids
Lipodystrophy D008060 4 associated lipids
Viremia D014766 4 associated lipids
Parvoviridae Infections D010322 4 associated lipids
Gallbladder Diseases D005705 3 associated lipids
Exostoses, Multiple Hereditary D005097 3 associated lipids
Pneumonia, Lipid D011017 2 associated lipids
Steatorrhea D045602 2 associated lipids
Fasciitis D005208 2 associated lipids
Ossification, Heterotopic D009999 2 associated lipids
Persian Gulf Syndrome D018923 1 associated lipids
Hemorrhagic Septicemia, Viral D031941 1 associated lipids
Per page 10 20 50 100 | Total 84

PubChem Associated disorders and diseases

What pathways are associated with (e,e,e,e)-squalene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with (e,e,e,e)-squalene?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (e,e,e,e)-squalene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (e,e,e,e)-squalene

Download all related citations
Per page 10 20 50 100 | Total 1766
Authors Title Published Journal PubMed Link
Palamarchuk VI et al. [Radiation-induced changes in the content of squalene, lathosterol and cholesterol in rat blood proteins]. 1991 May-Jun Radiobiologiia pmid:1887013
Vuoristo M et al. Cholesterol malabsorption in pancreatic insufficiency: effects of enzyme substitution. 1992 Gastroenterology pmid:1732134
Yeo HC and Shibamoto T Formation of formaldehyde and malonaldehyde by photooxidation of squalene. 1992 Lipids pmid:1608304
Melnykovych G et al. Growth inhibition of leukemia cell line CEM-C1 by farnesol: effects of phosphatidylcholine and diacylglycerol. 1992 Biochem. Biophys. Res. Commun. pmid:1632790
Nikkilä K et al. Serum and hepatic cholestanol, squalene and noncholesterol sterols in man: a study on liver transplantation. 1992 Hepatology pmid:1568728
Kamimura H et al. Enhanced elimination of theophylline, phenobarbital and strychnine from the bodies of rats and mice by squalane treatment. 1992 J. Pharmacobio-dyn. pmid:1527697
Schulz S et al. Mechanisms of cell growth inhibition and cell cycle arrest in human colonic adenocarcinoma cells by dehydroepiandrosterone: role of isoprenoid biosynthesis. 1992 Cancer Res. pmid:1531325
Allison AC and Byars NE Syntex adjuvant formulation. 1992 Res. Immunol. pmid:1439132
Bai M et al. Epoxidation of 2,3-oxidosqualene to 2,3;22,23-squalene dioxide by squalene epoxidase. 1992 Biochem. Biophys. Res. Commun. pmid:1599468
Van Sickle WA et al. Inhibition of cholesterol synthesis by cyclopropylamine derivatives of squalene in human hepatoblastoma cells in culture. 1992 Lipids pmid:1326069
Murakoshi M et al. Inhibition by squalene of the tumor-promoting activity of 12-O-tetradecanoylphorbol-13-acetate in mouse-skin carcinogenesis. 1992 Int. J. Cancer pmid:1334056
Sherman DR et al. Components of sterol biosynthesis assembled on the oxygen-avid hemoglobin of Ascaris. 1992 Science pmid:1470914
Tait RM Development of a radiometric spot-wash assay for squalene synthase. 1992 Anal. Biochem. pmid:1416027
Nikkilä K et al. Liver transplantation modifies serum cholestanol, cholesterol precursor and plant sterol levels. 1992 Clin. Chim. Acta pmid:1499139
Cenedella RJ et al. Cholesterylene, a newly recognized tissue lipid, found at high levels in the cornea. 1992 Biochem. Biophys. Res. Commun. pmid:1510688
Taton M et al. Inhibition of 2,3-oxidosqualene cyclases. 1992 Biochemistry pmid:1510977
Boutaud O et al. Preferential cyclization of 2,3(S):22(S),23-dioxidosqualene by mammalian 2,3-oxidosqualene-lanosterol cyclase. 1992 Biochem. Biophys. Res. Commun. pmid:1445330
Abe I et al. Affinity labeling of vertebrate oxidosqualene cyclases with a tritiated suicide substrate. 1992 Biochem. Biophys. Res. Commun. pmid:1520315
Ceruti M et al. 2,3-Epoxy-10-aza-10,11-dihydrosqualene, a high-energy intermediate analogue inhibitor of 2,3-oxidosqualene cyclase. 1992 J. Med. Chem. pmid:1501233
Silva CJ and Djerassi C Biosynthetic studies of marine lipids 36. The origin of common sterol side chains in eleven sponges using [3-3H]-squalene. 1992 Jan-Feb Comp. Biochem. Physiol., B pmid:1499273
Fujita H and Matsuo I Type I lipid photo-oxidation by the nonsteroidal anti-inflammatory drug suprofen: a possible key to its photosensitivity. 1992-1993 Oct Photodermatol Photoimmunol Photomed pmid:1342189
Ciosek CP et al. Lipophilic 1,1-bisphosphonates are potent squalene synthase inhibitors and orally active cholesterol lowering agents in vivo. 1993 J. Biol. Chem. pmid:8227045
Vanhanen HT et al. Serum cholesterol, cholesterol precursors, and plant sterols in hypercholesterolemic subjects with different apoE phenotypes during dietary sitostanol ester treatment. 1993 J. Lipid Res. pmid:8228636
Balliano G et al. 3-Carboxy-4-nitrophenyl-dithio-1,1',2-trisnorsqualene: a site-directed inactivator of yeast oxidosqualene cyclase. 1993 Lipids pmid:8246689
Corsini A et al. Relationship between mevalonate pathway and arterial myocyte proliferation: in vitro studies with inhibitors of HMG-CoA reductase. 1993 Atherosclerosis pmid:8216498
Mercer EI Inhibitors of sterol biosynthesis and their applications. 1993 Prog. Lipid Res. pmid:8309949
Lohner K et al. Squalene promotes the formation of non-bilayer structures in phospholipid model membranes. 1993 Biochim. Biophys. Acta pmid:8399307
Kawakami T et al. Squalane as a possible carrier of bone morphogenetic protein. 1993 Biomaterials pmid:8399948
Storm HM et al. Radioprotection of mice by dietary squalene. 1993 Lipids pmid:8355581
Balliano G et al. Differential inhibition of fungal oxidosqualene cyclase by 6E and 6Z isomers of 2,3-epoxy-10-aza-10,11-dihydrosqualene. 1993 FEBS Lett. pmid:8462686
Crispino GA et al. Selective perhydroxylation of squalene: taming the arithmetic demon. 1993 Science pmid:8418495
Asnis DS et al. Shark oil pneumonia. An overlooked entity. 1993 Chest pmid:8449116
Henk G and Heinz T [Hydrocarbon content in the fat of meat pigs after feeding "Fermosin"]. 1993 Arch Tierernahr pmid:8572916
Prashad M Amidinium cation as a mimic of allylic carbocation: synthesis and squalene synthetase inhibitory activity of an amidinium analog of a carbocation intermediate. 1993 J. Med. Chem. pmid:8496942
Horie M et al. An inhibitor of squalene epoxidase, NB-598, suppresses the secretion of cholesterol and triacylglycerol and simultaneously reduces apolipoprotein B in HepG2 cells. 1993 Biochim. Biophys. Acta pmid:8504141
Seo S et al. Effect of sterol biosynthesis inhibitor, SSF-109, on cholesterol synthesis in isolated rat hepatocytes. 1993 Steroids pmid:8484187
Someya K et al. The antioxidant effect of palm fruit carotene on skin lipid peroxidation in guinea pigs as estimated by chemiluminescence-HPLC method. 1994 J. Nutr. Sci. Vitaminol. pmid:7844638
Balliano G et al. Inhibition of sterol biosynthesis in Saccharomyces cerevisiae and Candida albicans by 22,23-epoxy-2-aza-2,3-dihydrosqualene and the corresponding N-oxide. 1994 Antimicrob. Agents Chemother. pmid:7810997
Kamimura N et al. Construction of squalene-accumulating Saccharomyces cerevisiae mutants by gene disruption through homologous recombination. 1994 Appl. Microbiol. Biotechnol. pmid:7765777
Rabiskova M et al. The influence of surface properties on uptake of oil into complex coacervate microcapsules. 1994 J. Pharm. Pharmacol. pmid:7815274
Fujita H and Matsuo I In vitro phototoxic activities of new quinolone antibacterial agents: lipid peroxidative potentials. 1994 Photodermatol Photoimmunol Photomed pmid:7880759
Hilgers LA et al. A novel non-mineral oil-based adjuvant. I. Efficacy of a synthetic sulfolipopolysaccharide in a squalane-in-water emulsion in laboratory animals. 1994 Vaccine pmid:8085385
Hilgers LA et al. A novel non-mineral oil-based adjuvant. II. Efficacy of a synthetic sulfolipopolysaccharide in a squalane-in-water emulsion in pigs. 1994 Vaccine pmid:8085386
Wieland B et al. Genetic and biochemical analyses of the biosynthesis of the yellow carotenoid 4,4'-diaponeurosporene of Staphylococcus aureus. 1994 J. Bacteriol. pmid:8002598
Byars NE et al. Vaccinating guinea pigs with recombinant glycoprotein D of herpes simplex virus in an efficacious adjuvant formulation elicits protection against vaginal infection. 1994 Vaccine pmid:8165851
Dollis D and Schuber F Effects of a 2,3-oxidosqualene-lanosterol cyclase inhibitor 2,3:22,23-dioxidosqualene and 24,25-epoxycholesterol on the regulation of cholesterol biosynthesis in human hepatoma cell line HepG2. 1994 Biochem. Pharmacol. pmid:8043030
Gylling H and Miettinen TA Postabsorptive metabolism of dietary squalene. 1994 Atherosclerosis pmid:8060377
Abe I [Bioorganic chemistry of squalene cyclase]. 1994 Tanpakushitsu Kakusan Koso pmid:8090933
Pogliani L et al. An NMR and molecular mechanics study of squalene and squalene derivatives. 1994 Chem. Phys. Lipids pmid:8013054
Giron MD et al. Mevalonate-mediated suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase function in alpha-toxin-perforated cells. 1994 Proc. Natl. Acad. Sci. U.S.A. pmid:8022795
Domnas A et al. Squalene metabolism in two species of Lagenidium. 1994 Can. J. Microbiol. pmid:8076247
Sunthornandh P and Ratanabanangkoon K A comparative study of three vehicles on antibody responses against elapid snake neurotoxin immunogens. 1994 Toxicon pmid:8079368
Ren Z and Gould MN Inhibition of ubiquinone and cholesterol synthesis by the monoterpene perillyl alcohol. 1994 Cancer Lett. pmid:8149348
Mookhtiar KA et al. Yeast squalene synthase. A mechanism for addition of substrates and activation by NADPH. 1994 J. Biol. Chem. pmid:8157649
Florin-Christensen M et al. Occurrence of specific sterols in Pneumocystis carinii. 1994 Biochem. Biophys. Res. Commun. pmid:8292026
Miettinen TA and Vanhanen H Serum concentration and metabolism of cholesterol during rapeseed oil and squalene feeding. 1994 Am. J. Clin. Nutr. pmid:8310985
Inoue H et al. Phosphorylation of farnesol by a cell-free system from Botryococcus braunii. 1994 Biochem. Biophys. Res. Commun. pmid:8179579
Ohkawa S et al. Immune responses induced by prototype vaccines for AIDS in rhesus monkeys. 1994 AIDS Res. Hum. Retroviruses pmid:8179961
Valensi JP et al. Systemic cytokine profiles in BALB/c mice immunized with trivalent influenza vaccine containing MF59 oil emulsion and other advanced adjuvants. 1994 J. Immunol. pmid:7930610
Kahn JO et al. Clinical and immunologic responses to human immunodeficiency virus (HIV) type 1SF2 gp120 subunit vaccine combined with MF59 adjuvant with or without muramyl tripeptide dipalmitoyl phosphatidylethanolamine in non-HIV-infected human volunteers. 1994 J. Infect. Dis. pmid:7963729
Hoffman SL et al. Safety, immunogenicity, and efficacy of a malaria sporozoite vaccine administered with monophosphoryl lipid A, cell wall skeleton of mycobacteria, and squalane as adjuvant. 1994 Am. J. Trop. Med. Hyg. pmid:7985753
Abe I et al. Inhibitors of squalene biosynthesis and metabolism. 1994 Nat Prod Rep pmid:15200015
Yoshino S and Yoshino J Recruitment of pathogenic T cells to synovial tissues of rats injected intraarticularly with nonspecific agents. 1994 Cell. Immunol. pmid:7522973
Gylling H et al. Postprandial vitamin A and squalene clearances and cholesterol synthesis off and on lovastatin treatment in type III hyperlipoproteinemia. 1995 Atherosclerosis pmid:7669084
Lees ND et al. Cloning of the late genes in the ergosterol biosynthetic pathway of Saccharomyces cerevisiae--a review. 1995 Lipids pmid:7791529
Abe I and Prestwich GD Identification of the active site of vertebrate oxidosqualene cyclase. 1995 Lipids pmid:7791531
Cattel L et al. 2,3-Oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors. 1995 Lipids pmid:7791532
Houston L et al. Response of guinea pigs to a vaccine containing a new adjuvant (SAF) and gram-negative bacteria. 1995 Lab. Anim. Sci. pmid:7752616
Langenberg AG et al. A recombinant glycoprotein vaccine for herpes simplex virus type 2: safety and immunogenicity [corrected]. 1995 Ann. Intern. Med. pmid:7755223
Yamamoto A et al. Impaired water barrier function in acne vulgaris. 1995 Arch. Dermatol. Res. pmid:7763094
Vanhanen HT and Miettinen TA Cholesterol absorption and synthesis during pravastatin, gemfibrozil and their combination. 1995 Atherosclerosis pmid:7661873
Fliesler SJ et al. Isoprenoid lipid metabolism in the retina: dynamics of squalene and cholesterol incorporation and turnover in frog rod outer segment membranes. 1995 Exp. Eye Res. pmid:7720806
Kerwin JL et al. Isoprenoid-mediated changes in the glycerophospholipid molecular species of the sterol auxotrophic fungus Lagenidium giganteum. 1995 Microbiology (Reading, Engl.) pmid:7704271
Ott G et al. Enhancement of humoral response against human influenza vaccine with the simple submicron oil/water emulsion adjuvant MF59. 1995 Vaccine pmid:8578842
Piretti MV et al. Simultaneous reversed-phase high-performance liquid chromatographic separation of non-polar isoprenoid lipids and their determination. 1995 J. Chromatogr. B, Biomed. Appl. pmid:8788146
Socaciu C et al. In vitro yeast (Saccharomyces cerevisiae) presqualene and squalene synthesis related to substrate and cofactor availability. 1995 C. R. Acad. Sci. III, Sci. Vie pmid:8521075
Boutaud O et al. Retention of the label during the conversion of [3-3H] squalene into (3S)-2,3-oxidosqualene catalyzed by mammalian squalene oxidase. 1995 Biochem. Biophys. Res. Commun. pmid:7887959
Robuccio JA et al. Comparison of the effects of five adjuvants on the antibody response to influenza virus antigen in guinea pigs. 1995 Lab. Anim. Sci. pmid:7474883
Lewis D et al. Enzyme inhibition during the conversion of squalene to cholesterol. 1995 Steroids pmid:7482633
Pittler SJ et al. In vivo requirement of protein prenylation for maintenance of retinal cytoarchitecture and photoreceptor structure. 1995 J. Cell Biol. pmid:7615641
Viola F et al. Inhibition of 2,3-oxidosqualene cyclase and sterol biosynthesis by 10- and 19-azasqualene derivatives. 1995 Biochem. Pharmacol. pmid:7575639
Ott G et al. MF59. Design and evaluation of a safe and potent adjuvant for human vaccines. 1995 Pharm Biotechnol pmid:7551221
Nagumo A et al. Purification and characterization of recombinant squalene epoxidase. 1995 J. Lipid Res. pmid:7595073
Airaudi D et al. Preliminary screening of some squalenoid derivatives for toxicity towards dermatophytes. 1995 Jul-Aug Mycoses pmid:8559196
Bonté F et al. Simarouba amara extract increases human skin keratinocyte differentiation. 1996 J Ethnopharmacol pmid:8844461
Traquina P et al. MF59 adjuvant enhances the antibody response to recombinant hepatitis B surface antigen vaccine in primates. 1996 J. Infect. Dis. pmid:8940205
Rangel H et al. Naturally azole-resistant Leishmania braziliensis promastigotes are rendered susceptible in the presence of terbinafine: comparative study with azole-susceptible Leishmania mexicana promastigotes. 1996 Antimicrob. Agents Chemother. pmid:9124841
Gylling H et al. Delayed postprandial retinyl palmitate and squalene removal in a patient heterozygous for apolipoprotein A-IFIN mutation (Leu 159-->Arg) and low HDL cholesterol level without coronary artery disease. 1996 Atherosclerosis pmid:9125314
Fujie T et al. Culture of cells derived from the human sebaceous gland under serum-free conditions without a biological feeder layer or specific matrices. 1996 Arch. Dermatol. Res. pmid:8931874
Grimes DS et al. Sunlight, cholesterol and coronary heart disease. 1996 QJM pmid:8935479
Krisans SK Cell compartmentalization of cholesterol biosynthesis. 1996 Ann. N. Y. Acad. Sci. pmid:8993542
Nikkilä K et al. Serum squalene and noncholesterol sterols before and after delivery in normal and cholestatic pregnancy. 1996 J. Lipid Res. pmid:9017519
Keefer MC et al. Safety and immunogenicity of Env 2-3, a human immunodeficiency virus type 1 candidate vaccine, in combination with a novel adjuvant, MTP-PE/MF59. NIAID AIDS Vaccine Evaluation Group. 1996 AIDS Res. Hum. Retroviruses pmid:8744579
Dracheva S et al. Chemical and functional studies on the importance of purple membrane lipids in bacteriorhodopsin photocycle behavior. 1996 FEBS Lett. pmid:8612754
Ito T et al. Hepatic cholesterol metabolism in patients with cholesterol gallstones: enhanced intracellular transport of cholesterol. 1996 Gastroenterology pmid:8613070
Chan C et al. The squalestatins: decarboxy and 4-deoxy analogues as potent squalene synthase inhibitors. 1996 J. Med. Chem. pmid:8568810
Miquel K et al. Farnesol and geranylgeraniol induce actin cytoskeleton disorganization and apoptosis in A549 lung adenocarcinoma cells. 1996 Biochem. Biophys. Res. Commun. pmid:8780704
Higgins DA et al. MF59 adjuvant enhances the immunogenicity of influenza vaccine in both young and old mice. 1996 Vaccine pmid:8782343
Mark M et al. Effects of a novel 2,3-oxidosqualene cyclase inhibitor on the regulation of cholesterol biosynthesis in HepG2 cells. 1996 J. Lipid Res. pmid:8820110
Arthington-Skaggs BA et al. Positive and negative regulation of a sterol biosynthetic gene (ERG3) in the post-squalene portion of the yeast ergosterol pathway. 1996 FEBS Lett. pmid:8772195