(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Owen RW et al. | Phenolic compounds and squalene in olive oils: the concentration and antioxidant potential of total phenols, simple phenols, secoiridoids, lignansand squalene. | 2000 | Food Chem. Toxicol. | pmid:10908812 |
Maes D et al. | Noninvasive techniques for measuring oxidation products on the surface of human skin. | 2000 | Meth. Enzymol. | pmid:10907548 |
Nakano M et al. | 3-(4'-methyl-1'-naphthyl)propionic acid, 1',4'-endoperoxide for dioxygenation of squalene and for bacterial killing. | 2000 | Meth. Enzymol. | pmid:10907513 |
Kohashi O and Pearson CM | Arthritogenicity of Mycobacterium smegmatis subfractions, related to different oil vehicle and different composition. | 1976 | Int. Arch. Allergy Appl. Immunol. | pmid:1085757 |
Carlson BC et al. | The endogenous adjuvant squalene can induce a chronic T-cell-mediated arthritis in rats. | 2000 | Am. J. Pathol. | pmid:10854227 |
Chiba K et al. | Comedogenicity of squalene monohydroperoxide in the skin after topical application. | 2000 | J Toxicol Sci | pmid:10845185 |
Rhodes CJ et al. | "Spin-labelling" with the second hydrogen radioisotope: radicals formed from squalene by muonium addition. | 2000 | Free Radic. Res. | pmid:10826923 |
Alving CR and Grabenstein JD | Re: Antibodies to squalene in Gulf War Syndrome. | 2000 | Exp. Mol. Pathol. | pmid:10816387 |
Viola F et al. | Rationally designed inhibitors as tools for comparing the mechanism of squalene-hopene cyclase with oxidosqualene cyclase. | 2000 | Lipids | pmid:10783007 |
Relas H et al. | Effect of stanol ester on postabsorptive squalene and retinyl palmitate. | 2000 | Metab. Clin. Exp. | pmid:10778871 |