(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Global Advisory Committee on Vaccine Safety, 6-7 June 2006. | 2006 | Wkly. Epidemiol. Rec. | pmid:16841398 | |
Richter E et al. | Stimulation of the faecal excretion of 2,4,5,2',4',5'-hexachlorobiphenyl in rats by squalane. | 1983 | Xenobiotica | pmid:6415933 |
Hu JJ et al. | [Antibody production and its neutralization of Abeta42's cytoxicity in BALB/c mice induced by Abeta42 and its subunit vaccines]. | 2004 | Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi | pmid:15191720 |
Ikekawa T et al. | [Studies on antitumor activity of squalene and its related compounds]. | 1986 | Yakugaku Zasshi | pmid:3772729 |
Tsai TF | MF59 adjuvanted seasonal and pandemic influenza vaccines. | 2011 | Yakugaku Zasshi | pmid:22129867 |
Abe I | [Engineering of squalene cyclizing enzymes]. | 2008 | Yakugaku Zasshi | pmid:18670176 |
Zhang Y et al. | [Chemical constituents from the mangrove plant Ceriops tagal]. | 2005 | Yao Xue Xue Bao | pmid:16408813 |
Sondergaard E et al. | Alimentary production of gallstones in hamsters. 28. Influence of isomerized squalene on gallstone production. | 1974 | Z Ernahrungswiss | pmid:4450595 |
Dam H et al. | Alimentary production of gallstones in hamsters. 27. Influence of supplementation of the gallstone producing diet with squalene, cholesterol, certain other sterols, fish oil fatty acid ethyl esters, and modification of the basal diet on gallstone production and levels of cholesterol in serum and liver. | 1974 | Z Ernahrungswiss | pmid:4615449 |
Kipping D | [Observations on skin surface fats]. | 1965 | Z Haut Geschlechtskr | pmid:5860995 |
Gloor M | [The significance of physiological and biochemical deviations from the norm on the skin surface for infectious skin diseases (proceedings)]. | 1976 | Z. Hautkr. | pmid:13544 |
de la Puerta R et al. | Effect of minor components of virgin olive oil on topical antiinflammatory assays. | 2000 Sep-Oct | Z. Naturforsch., C, J. Biosci. | pmid:11098836 |
Kopena R et al. | Lipophilic compounds from the femoral gland secretions of male Hungarian green lizards, Lacerta viridis. | 2009 May-Jun | Z. Naturforsch., C, J. Biosci. | pmid:19678551 |
Liu Y et al. | [Researches on influence of squalene synthase gene polymorphism on catalytic efficiency of its encode enzyme in Glycyrrhiza uralensis]. | 2012 | Zhongguo Zhong Yao Za Zhi | pmid:23627178 |
Li RC et al. | [Study on the safety and immunogenicity of MF59-adjuvanted influenza subunit vaccine in Chinese elderly]. | 2008 | Zhonghua Liu Xing Bing Xue Za Zhi | pmid:19040034 |