(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Downing DT et al. | The time course of lipid formation in human sebaceous glands. | 1977 | J. Invest. Dermatol. | pmid:903669 |
BeytÃa ED and Porter JW | Biochemistry of polyisoprenoid biosynthesis. | 1976 | Annu. Rev. Biochem. | pmid:9026 |
Nikkilä K et al. | Serum squalene and noncholesterol sterols before and after delivery in normal and cholestatic pregnancy. | 1996 | J. Lipid Res. | pmid:9017519 |
Stach D et al. | Synthesis and inhibition studies of sulfur-substituted squalene oxide analogues as mechanism-based inhibitors of 2,3-oxidosqualene-lanosterol cyclase. | 1997 | J. Med. Chem. | pmid:9003518 |
Krisans SK | Cell compartmentalization of cholesterol biosynthesis. | 1996 | Ann. N. Y. Acad. Sci. | pmid:8993542 |
Traquina P et al. | MF59 adjuvant enhances the antibody response to recombinant hepatitis B surface antigen vaccine in primates. | 1996 | J. Infect. Dis. | pmid:8940205 |
Grimes DS et al. | Sunlight, cholesterol and coronary heart disease. | 1996 | QJM | pmid:8935479 |
Fujie T et al. | Culture of cells derived from the human sebaceous gland under serum-free conditions without a biological feeder layer or specific matrices. | 1996 | Arch. Dermatol. Res. | pmid:8931874 |
Kohashi O et al. | Effect of oil composition on both adjuvant-induced arthritis and delayed hypersensitivity to purified protein derivative and peptidoglycans in various rat strains. | 1977 | Infect. Immun. | pmid:892904 |
Dogliotti M et al. | Nutritional influences of pellagra on sebum composition. | 1977 | Br. J. Dermatol. | pmid:889695 |