| MeSH term | MeSH ID | Detail |
|---|---|---|
| Persian Gulf Syndrome | D018923 | 1 associated lipids |
| Hemorrhagic Septicemia, Viral | D031941 | 1 associated lipids |
| Fasciitis | D005208 | 2 associated lipids |
| Ossification, Heterotopic | D009999 | 2 associated lipids |
| Pneumonia, Lipid | D011017 | 2 associated lipids |
| Steatorrhea | D045602 | 2 associated lipids |
| Gallbladder Diseases | D005705 | 3 associated lipids |
| Exostoses, Multiple Hereditary | D005097 | 3 associated lipids |
| Parvoviridae Infections | D010322 | 4 associated lipids |
| Simian Acquired Immunodeficiency Syndrome | D016097 | 4 associated lipids |
| Coronavirus Infections | D018352 | 4 associated lipids |
| Hyperlipoproteinemia Type III | D006952 | 4 associated lipids |
| Viremia | D014766 | 4 associated lipids |
| Lipodystrophy | D008060 | 4 associated lipids |
| Tinea Versicolor | D014010 | 5 associated lipids |
| Keratitis, Herpetic | D016849 | 5 associated lipids |
| Leukemia, Hairy Cell | D007943 | 5 associated lipids |
| Parasitemia | D018512 | 5 associated lipids |
| Alopecia Areata | D000506 | 6 associated lipids |
| Chronic Disease | D002908 | 7 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Richter E and Schäfer SG | The effect of squalane on the absorption of dietary cholesterol by the rat. | 1982 | Res Exp Med (Berl) | pmid:7100640 |
| Naziri E and Tsimidou MZ | Formulated squalene for food related applications. | 2013 | Recent Pat Food Nutr Agric | pmid:23270393 |
| Camin F et al. | Stable isotope ratios of carbon and hydrogen to distinguish olive oil from shark squalene-squalane. | 2010 | Rapid Commun. Mass Spectrom. | pmid:20499327 |
| Zambonin CG et al. | Laser desorption/ionization time-of-flight mass spectrometry of squalene in oil samples. | 2006 | Rapid Commun. Mass Spectrom. | pmid:16345138 |
| Palamarchuk VI et al. | [Radiation-induced changes in the content of squalene, lathosterol and cholesterol in rat blood proteins]. | 1991 May-Jun | Radiobiologiia | pmid:1887013 |
| Palamarchuk VI | [Characteristics of the radiation-induced changes in the content of sterols and squalene in the lymphoid system tissues and erythrocyte membranes of rats]. | 1990 May-Jun | Radiobiologiia | pmid:2371389 |
| Novoselova EG and KolomiÄtseva IK | [Early radiation impairments of the metabolism of cholesterol, squalene and ubiquinone in rat liver]. | 1976 Jul-Aug | Radiobiologiia | pmid:996254 |
| Limberti A et al. | [Squalene-cholesterol ratio in the amniotic fluid and gestational age: changes in the threshold in relation to the preparation of the sample]. | 1986 | Quad Sclavo Diagn | pmid:3786665 |
| Grimes DS et al. | Sunlight, cholesterol and coronary heart disease. | 1996 | QJM | pmid:8935479 |
| Szostak WB and Szostak-Wegierek D | [Health properties of shark oil]. | 2006 | Prz. Lek. | pmid:17083160 |
| Buddhan S et al. | Protective effect of dietary squalene supplementation on mitochondrial function in liver of aged rats. | 2007 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:17574827 |
| Mercer EI | Inhibitors of sterol biosynthesis and their applications. | 1993 | Prog. Lipid Res. | pmid:8309949 |
| Haines TH | Do sterols reduce proton and sodium leaks through lipid bilayers? | 2001 | Prog. Lipid Res. | pmid:11412894 |
| Bazzano G and Bazzano GS | Hypocholesterolemic effect of -ketoglutarate in the Mongolian gerbil. | 1972 | Proc. Soc. Exp. Biol. Med. | pmid:5033114 |
| Fiser RH et al. | Effects of acute infection on cholesterogenesis in the rhesus monkey. | 1971 | Proc. Soc. Exp. Biol. Med. | pmid:4399094 |
| SHORB MS et al. | EFFECT OF TRIPARANOL ON SYNTHESIS OF SQUALENE AND TETRAHYMANOL BY TETRAHYMENA PYRIFORMIS. | 1965 | Proc. Soc. Exp. Biol. Med. | pmid:14277681 |
| ALEXANDER GJ and ALEXANDER RB | INHIBITION OF CHOLESTEROL SYNTHESIS IN VIVO BY A CONVULSANT, METRAZOL. | 1964 | Proc. Soc. Exp. Biol. Med. | pmid:14117448 |
| BURGESS TL and WILSON JD | Studies on hormonal regulation of squalene synthesis in preputial gland and skin of the rat. | 1963 | Proc. Soc. Exp. Biol. Med. | pmid:14016990 |
| PATTERSON JF | Biosynthesis of squalene by rat preputial gland. | 1960 | Proc. Soc. Exp. Biol. Med. | pmid:13733368 |
| FLESCH P | Hair loss from squalene. | 1951 | Proc. Soc. Exp. Biol. Med. | pmid:14844354 |