(e,e,e,e)-squalene

(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (e,e,e,e)-squalene?

(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene

MeSH term MeSH ID Detail
Hemorrhagic Septicemia, Viral D031941 1 associated lipids
Persian Gulf Syndrome D018923 1 associated lipids
Fasciitis D005208 2 associated lipids
Ossification, Heterotopic D009999 2 associated lipids
Pneumonia, Lipid D011017 2 associated lipids
Steatorrhea D045602 2 associated lipids
Gallbladder Diseases D005705 3 associated lipids
Exostoses, Multiple Hereditary D005097 3 associated lipids
Hyperlipoproteinemia Type III D006952 4 associated lipids
Coronavirus Infections D018352 4 associated lipids
Lipodystrophy D008060 4 associated lipids
Viremia D014766 4 associated lipids
Parvoviridae Infections D010322 4 associated lipids
Simian Acquired Immunodeficiency Syndrome D016097 4 associated lipids
Parasitemia D018512 5 associated lipids
Tinea Versicolor D014010 5 associated lipids
Keratitis, Herpetic D016849 5 associated lipids
Leukemia, Hairy Cell D007943 5 associated lipids
Alopecia Areata D000506 6 associated lipids
Chronic Disease D002908 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with (e,e,e,e)-squalene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (e,e,e,e)-squalene?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (e,e,e,e)-squalene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (e,e,e,e)-squalene

Download all related citations
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Authors Title Published Journal PubMed Link
Kribii R et al. Cloning and characterization of the Arabidopsis thaliana SQS1 gene encoding squalene synthase--involvement of the C-terminal region of the enzyme in the channeling of squalene through the sterol pathway. 1997 Eur. J. Biochem. pmid:9363754
Cataldo DM and Van Nest G The adjuvant MF59 increases the immunogenicity and protective efficacy of subunit influenza vaccine in mice. 1997 Vaccine pmid:9364672
Tomasi M et al. Strong mucosal adjuvanticity of cholera toxin within lipid particles of a new multiple emulsion delivery system for oral immunization. 1997 Eur. J. Immunol. pmid:9368632
Salamon Z et al. Coupled plasmon-waveguide resonators: a new spectroscopic tool for probing proteolipid film structure and properties. 1997 Biophys. J. pmid:9370473
Toews AD et al. Tellurium causes dose-dependent coordinate down-regulation of myelin gene expression. 1997 Brain Res. Mol. Brain Res. pmid:9387870
Gloor M et al. Biochemical and physiological parameters on the healthy skin surface of patients with common warts. 1976 Dermatologica pmid:939341
Law S et al. Skin surface lipids inhibit adherence of Candida albicans to stratum corneum. 1997 Dermatology (Basel) pmid:9407165
Newmark HL Squalene, olive oil, and cancer risk: a review and hypothesis. 1997 Cancer Epidemiol. Biomarkers Prev. pmid:9419410
Ceruti M et al. 29-Methylidene-2,3-oxidosqualene derivatives as stereospecific mechanism-based inhibitors of liver and yeast oxidosqualene cyclase. 1998 J. Med. Chem. pmid:9484504
Rao CV et al. Chemopreventive effect of squalene on colon cancer. 1998 Carcinogenesis pmid:9498278