| MeSH term | MeSH ID | Detail |
|---|---|---|
| Persian Gulf Syndrome | D018923 | 1 associated lipids |
| Hemorrhagic Septicemia, Viral | D031941 | 1 associated lipids |
| Pneumonia, Lipid | D011017 | 2 associated lipids |
| Steatorrhea | D045602 | 2 associated lipids |
| Ossification, Heterotopic | D009999 | 2 associated lipids |
| Fasciitis | D005208 | 2 associated lipids |
| Gallbladder Diseases | D005705 | 3 associated lipids |
| Exostoses, Multiple Hereditary | D005097 | 3 associated lipids |
| Simian Acquired Immunodeficiency Syndrome | D016097 | 4 associated lipids |
| Hyperlipoproteinemia Type III | D006952 | 4 associated lipids |
| Coronavirus Infections | D018352 | 4 associated lipids |
| Lipodystrophy | D008060 | 4 associated lipids |
| Viremia | D014766 | 4 associated lipids |
| Parvoviridae Infections | D010322 | 4 associated lipids |
| Keratitis, Herpetic | D016849 | 5 associated lipids |
| Leukemia, Hairy Cell | D007943 | 5 associated lipids |
| Parasitemia | D018512 | 5 associated lipids |
| Tinea Versicolor | D014010 | 5 associated lipids |
| Alopecia Areata | D000506 | 6 associated lipids |
| Chronic Disease | D002908 | 7 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Vesikari T et al. | Homologous and heterologous antibody responses to a one-year booster dose of an MF59(®) adjuvanted A/H5N1 pre-pandemic influenza vaccine in pediatric subjects. | 2012 | Hum Vaccin Immunother | pmid:22777094 |
| Bencharitiwong R et al. | In vitro assessment of the allergenicity of novel MF59-adjuvanted pandemic H1N1 influenza vaccine produced in dog kidney cells. | 2012 | Hum Vaccin Immunother | pmid:22777093 |
| Ambrose CS and Belshe RB | Influenza vaccine in young children. | 2012 | N. Engl. J. Med. | pmid:22276839 |
| Heikkinen T and Heinonen S | Influenza vaccine in young children. | 2012 | N. Engl. J. Med. | pmid:22276840 |
| Gasparini R et al. | Aflunov(®): a prepandemic influenza vaccine. | 2012 | Expert Rev Vaccines | pmid:22309663 |
| Spanova M et al. | Influence of squalene on lipid particle/droplet and membrane organization in the yeast Saccharomyces cerevisiae. | 2012 | Biochim. Biophys. Acta | pmid:22342273 |
| Palma P et al. | Safety and immunogenicity of a monovalent MF59®-adjuvanted A/H1N1 vaccine in HIV-infected children and young adults. | 2012 | Biologicals | pmid:22261282 |
| Heikkinen T et al. | Safety of MF59-adjuvanted A/H1N1 influenza vaccine in pregnancy: a comparative cohort study. | 2012 | Am. J. Obstet. Gynecol. | pmid:22939717 |
| Mannino S et al. | Effectiveness of adjuvanted influenza vaccination in elderly subjects in northern Italy. | 2012 | Am. J. Epidemiol. | pmid:22940713 |
| Marinaro M et al. | A caprine herpesvirus 1 vaccine adjuvanted with MF59â„¢ protects against vaginal infection and interferes with the establishment of latency in goats. | 2012 | PLoS ONE | pmid:22511971 |
| Cosco D et al. | Self-assembled squalenoyl-cytarabine nanostructures as a potent nanomedicine for treatment of leukemic diseases. | 2012 | Int J Nanomedicine | pmid:22679366 |
| O'Hagan DT et al. | The mechanism of action of MF59 - an innately attractive adjuvant formulation. | 2012 | Vaccine | pmid:22682289 |
| Lokvam J and Fine PV | An oxidized squalene derivative from Protium subserratum Engl. (Engl.) growing in Peru. | 2012 | Molecules | pmid:22706374 |
| Yu S et al. | Novel Th1-biased adjuvant, SPO1, enhances mucosal and systemic immunogenicity of vaccines administered intranasally in mice. | 2012 | Vaccine | pmid:22709954 |
| Peric M et al. | Electron paramagnetic resonance line shifts and line shape changes due to heisenberg spin exchange and dipole-dipole interactions of nitroxide free radicals in liquids 8. Further experimental and theoretical efforts to separate the effects of the two interactions. | 2012 | J Phys Chem A | pmid:22288424 |
| Bihari I et al. | Assessment of antigen-specific and cross-reactive antibody responses to an MF59-adjuvanted A/H5N1 prepandemic influenza vaccine in adult and elderly subjects. | 2012 | Clin. Vaccine Immunol. | pmid:23081815 |
| Tetsutani K and Ishii KJ | Adjuvants in influenza vaccines. | 2012 | Vaccine | pmid:23084848 |
| Liu YT et al. | Protein engineering of Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase into parkeol synthase. | 2012 | Org. Lett. | pmid:23043506 |
| Ta MT et al. | Accumulation of squalene is associated with the clustering of lipid droplets. | 2012 | FEBS J. | pmid:23013491 |
| Nielsen AB et al. | Immune response after one or two doses of pandemic influenza A (H1N1) monovalent, AS03-adjuvanted vaccine in HIV infected adults. | 2012 | Vaccine | pmid:23036498 |