| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Dermatitis, Occupational | D009783 | 12 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Arthritis, Experimental | D001169 | 24 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Cornforth JW et al. | Studies on the biosynthesis of cholesterol. XVII. The asymmetric synthesis of a symmetrical molecule. | 1966 | Proc. R. Soc. Lond., B, Biol. Sci. | pmid:4379289 |
| Villee CA et al. | The regulation of the biosynthesis of sterols and steroids in the placenta. | 1966 | Adv. Enzyme Regul. | pmid:4862939 |
| Gaylor JL et al. | Preparation and properties of a cell-free system from rat skin that catalyzes sterol biosynthesis. | 1966 | J. Lipid Res. | pmid:4290536 |
| Lynen F | [The biochemical basis of the biosynthesis of cholesterol and fatty acids]. | 1966 | Wien. Klin. Wochenschr. | pmid:4296920 |
| Ismail AA et al. | Interrelation between thyroid hormones and essential fatty acids. | 1966 | Acta Physiol Acad Sci Hung | pmid:5953398 |
| Zelewski L and Villee CA | The biosynthesis of squalene, lanosterol, and cholesterol by minced human placenta. | 1966 | Biochemistry | pmid:5963423 |
| Paoletti P et al. | Lipid biosynthesis from labelled precursors in an experimental brain tumor-bearing mouse. | 1966 | Neurochirurgia (Stuttg) | pmid:5966653 |
| Williams RJ et al. | A possible mechanism for the biosynthesis of eschscholtzxanthin. | 1966 | Biochim. Biophys. Acta | pmid:5966716 |
| Cory EJ et al. | 2,3-oxidosqualene, an intermediate in the biological synthesis of sterols from squalene. | 1966 | J. Am. Chem. Soc. | pmid:5918046 |
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| Van Tamelen EE et al. | Enzymic conversion of squalene 2,3-oxide to lanosterol and cholesterol. | 1966 | J. Am. Chem. Soc. | pmid:5918048 |
| Garbuzov AG et al. | Presence of squalene in human aorta. | 1966 May-Jun | Fed Proc Transl Suppl | pmid:5222095 |
| Cherkes AI and Klebanov BM | [Cholesterine synthesis as an object of the action of drugs. (Review of the literature)]. | 1966 Nov-Dec | Farmakol Toksikol | pmid:6000378 |
| Blumer M | Hydrocarbons in digestive tract and liver of a basking shark. | 1967 | Science | pmid:5609822 |
| Grob EC and Csupor L | [Information on the leaf lipids of Acer platanoides L. during autumn yellowing]. | 1967 | Experientia | pmid:6077859 |
| Cain CE et al. | Hydrocarbons from human meninges and meningiomas. | 1967 | Biochim. Biophys. Acta | pmid:6078120 |
| Graebe JE | Isoprenoid biosynthesis in a cell-free system from pea shoots. | 1967 | Science | pmid:4381746 |
| Charlton JM et al. | Incorporation of 2-[14C]mevalonic acid into phytoene by isolated chloroplasts. | 1967 | Biochem. J. | pmid:4383323 |
| Voogt PA | Biosynthesis of 3-beta-sterols in a snail, Arion rufus L., from 1-14C-acetate. | 1967 | Arch. Int. Physiol. Biochim. | pmid:4167714 |
| Frantz ID and Schroepfer GJ | Sterol biosynthesis. | 1967 | Annu. Rev. Biochem. | pmid:18257735 |