(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Arias JL et al. | Squalene based nanocomposites: a new platform for the design of multifunctional pharmaceutical theragnostics. | 2011 | ACS Nano | pmid:21275408 |
van den Brand JM et al. | Efficacy of vaccination with different combinations of MF59-adjuvanted and nonadjuvanted seasonal and pandemic influenza vaccines against pandemic H1N1 (2009) influenza virus infection in ferrets. | 2011 | J. Virol. | pmid:21209108 |
Calabro S et al. | Vaccine adjuvants alum and MF59 induce rapid recruitment of neutrophils and monocytes that participate in antigen transport to draining lymph nodes. | 2011 | Vaccine | pmid:21215831 |
Javelle E et al. | Delayed focal lipoatrophy after AS03-adjuvanted influenza A (H1N1) 2009 vaccine. | 2011 | Vaccine | pmid:21172376 |
Montagnani S et al. | Autoimmune hemolytic anemia following MF59-adjuvanted influenza vaccine administration: a report of two cases. | 2011 | Ann Pharmacother | pmid:21189364 |
Esposito S et al. | Pandemic influenza A/H1N1 vaccine administered sequentially or simultaneously with seasonal influenza vaccine to HIV-infected children and adolescents. | 2011 | Vaccine | pmid:21199699 |
Bernstein DI | Vaccines for cytomegalovirus. | 2011 | Infect Disord Drug Targets | pmid:22309618 |
Fabbiani M et al. | Immune response to influenza A (H1N1)v monovalent MF59-adjuvanted vaccine in HIV-infected patients. | 2011 | Vaccine | pmid:21349364 |
Gill S et al. | Cholesterol-dependent degradation of squalene monooxygenase, a control point in cholesterol synthesis beyond HMG-CoA reductase. | 2011 | Cell Metab. | pmid:21356516 |
Cheong HJ et al. | Immunogenicity and safety of the influenza A/H1N1 2009 inactivated split-virus vaccine in young and older adults: MF59-adjuvanted vaccine versus nonadjuvanted vaccine. | 2011 | Clin. Vaccine Immunol. | pmid:21715575 |
Soto G et al. | Acetoacetyl-CoA thiolase regulates the mevalonate pathway during abiotic stress adaptation. | 2011 | J. Exp. Bot. | pmid:21908473 |
Achiraman S et al. | Increased squalene concentrations in the clitoral gland during the estrous cycle in rats: an estrus-indicating scent mark? | 2011 | Theriogenology | pmid:21924481 |
Brito LA et al. | An alternative renewable source of squalene for use in emulsion adjuvants. | 2011 | Vaccine | pmid:21723355 |
Gao J et al. | Laser-induced acoustic desorption/atmospheric pressure chemical ionization mass spectrometry. | 2011 | J. Am. Soc. Mass Spectrom. | pmid:21472571 |
Weschler CJ et al. | Squalene and cholesterol in dust from danish homes and daycare centers. | 2011 | Environ. Sci. Technol. | pmid:21476540 |
Cauda V et al. | "Liquid-phase calcination" of colloidal mesoporous silica nanoparticles in high-boiling solvents. | 2011 | J. Am. Chem. Soc. | pmid:21480591 |
Griffiths PD et al. | Cytomegalovirus glycoprotein-B vaccine with MF59 adjuvant in transplant recipients: a phase 2 randomised placebo-controlled trial. | 2011 | Lancet | pmid:21481708 |
Liu CL et al. | The direct observation of secondary radical chain chemistry in the heterogeneous reaction of chlorine atoms with submicron squalane droplets. | 2011 | Phys Chem Chem Phys | pmid:21455529 |
Inagaki YS et al. | Investigation of the potential for triterpene synthesis in rice through genome mining and metabolic engineering. | 2011 | New Phytol. | pmid:21501172 |
Garcia-Sicilia J et al. | Immunogenicity and safety of AS03-adjuvanted H1N1 pandemic vaccines in children and adolescents. | 2011 | Vaccine | pmid:21504774 |