(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Metzger P et al. | Botryolins A and B, two tetramethylsqualene triethers from the green microalga Botryococcus braunii. | 2002 | Phytochemistry | pmid:11937163 |
| Quang DN et al. | Concentriols B, C and D, three squalene-type triterpenoids from the ascomycete Daldinia concentrica. | 2002 | Phytochemistry | pmid:12359521 |
| Catalán CA et al. | A linear sesterterpene, two squalene derivatives and two peptide derivatives from Croton hieronymi. | 2003 | Phytochemistry | pmid:12943786 |
| Xu R et al. | On the origins of triterpenoid skeletal diversity. | 2004 | Phytochemistry | pmid:14751299 |
| Achitouv E et al. | C31-C34 methylated squalenes from a Bolivian strain of Botryococcus braunii. | 2004 | Phytochemistry | pmid:15541746 |
| Metzger P et al. | Braunicetals: acetals from condensation of macrocyclic aldehydes and terpene diols in Botryococcus braunii. | 2008 | Phytochemistry | pmid:18639308 |
| Packwood DM and Phillips LF | A stochastic, local mode study of neon-liquid surface collision dynamics. | 2011 | Phys Chem Chem Phys | pmid:21042647 |
| Liu CL et al. | The direct observation of secondary radical chain chemistry in the heterogeneous reaction of chlorine atoms with submicron squalane droplets. | 2011 | Phys Chem Chem Phys | pmid:21455529 |
| Wilson KR et al. | The statistical evolution of multiple generations of oxidation products in the photochemical aging of chemically reduced organic aerosol. | 2012 | Phys Chem Chem Phys | pmid:22158973 |
| King KL et al. | Inelastic scattering of OH radicals from organic liquids: isolating the thermal desorption channel. | 2013 | Phys Chem Chem Phys | pmid:23807737 |
| Binks BP et al. | How membrane permeation is affected by donor delivery solvent. | 2012 | Phys Chem Chem Phys | pmid:23073464 |
| Matsuo I et al. | Possible involvement of oxidation of lipids in inducing griseofulvin photosensitivity. | 1990 | Photodermatol Photoimmunol Photomed | pmid:2091745 |
| Picardo M et al. | Squalene peroxides may contribute to ultraviolet light-induced immunological effects. | 1991 | Photodermatol Photoimmunol Photomed | pmid:1804289 |
| Fujita H and Matsuo I | Type I lipid photo-oxidation by the nonsteroidal anti-inflammatory drug suprofen: a possible key to its photosensitivity. | 1992-1993 Oct | Photodermatol Photoimmunol Photomed | pmid:1342189 |
| Fujita H and Matsuo I | In vitro phototoxic activities of new quinolone antibacterial agents: lipid peroxidative potentials. | 1994 | Photodermatol Photoimmunol Photomed | pmid:7880759 |
| Kawada A et al. | In vitro phototoxicity of new quinolones: production of active oxygen species and photosensitized lipid peroxidation. | 1999 | Photodermatol Photoimmunol Photomed | pmid:10599972 |
| Dennis KJ and Shibamoto T | Production of malonaldehyde from squalene, a major skin surface lipid, during UV-irradiation. | 1989 | Photochem. Photobiol. | pmid:2756005 |
| Sabeena Farvin KH et al. | Effect of squalene on tissue defense system in isoproterenol-induced myocardial infarction in rats. | 2004 | Pharmacol. Res. | pmid:15225664 |
| Morin RJ and Srikantaiah MV | Inhibition of rat liver sterol formation by isoprenoid and conjugated ene compounds. | 1982 | Pharmacol Res Commun | pmid:7156175 |
| Baudner BC et al. | MF59 emulsion is an effective delivery system for a synthetic TLR4 agonist (E6020). | 2009 | Pharm. Res. | pmid:19255727 |