(e,e,e,e)-squalene

(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (e,e,e,e)-squalene?

(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene

MeSH term MeSH ID Detail
Hemorrhagic Septicemia, Viral D031941 1 associated lipids
Persian Gulf Syndrome D018923 1 associated lipids
Fasciitis D005208 2 associated lipids
Ossification, Heterotopic D009999 2 associated lipids
Pneumonia, Lipid D011017 2 associated lipids
Steatorrhea D045602 2 associated lipids
Gallbladder Diseases D005705 3 associated lipids
Exostoses, Multiple Hereditary D005097 3 associated lipids
Hyperlipoproteinemia Type III D006952 4 associated lipids
Coronavirus Infections D018352 4 associated lipids
Lipodystrophy D008060 4 associated lipids
Viremia D014766 4 associated lipids
Parvoviridae Infections D010322 4 associated lipids
Simian Acquired Immunodeficiency Syndrome D016097 4 associated lipids
Parasitemia D018512 5 associated lipids
Tinea Versicolor D014010 5 associated lipids
Keratitis, Herpetic D016849 5 associated lipids
Leukemia, Hairy Cell D007943 5 associated lipids
Alopecia Areata D000506 6 associated lipids
Chronic Disease D002908 7 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Fibrosarcoma D005354 8 associated lipids
Chondrodysplasia Punctata D002806 8 associated lipids
Fatigue D005221 10 associated lipids
Hepatitis D006505 11 associated lipids
Pregnancy Complications, Infectious D011251 11 associated lipids
Scalp Dermatoses D012536 11 associated lipids
Influenza, Human D007251 11 associated lipids
Dermatitis, Occupational D009783 12 associated lipids
Keloid D007627 12 associated lipids
Otitis Media D010033 12 associated lipids
Rosacea D012393 13 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Demyelinating Diseases D003711 15 associated lipids
Cholelithiasis D002769 16 associated lipids
Celiac Disease D002446 16 associated lipids
Olfaction Disorders D000857 17 associated lipids
Xanthomatosis D014973 17 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Periodontitis D010518 22 associated lipids
Cholestasis D002779 23 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Niemann-Pick Diseases D009542 25 associated lipids
Brain Diseases D001927 27 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Acne Vulgaris D000152 35 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with (e,e,e,e)-squalene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (e,e,e,e)-squalene?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (e,e,e,e)-squalene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (e,e,e,e)-squalene

Download all related citations
Per page 10 20 50 100 | Total 1766
Authors Title Published Journal PubMed Link
Van Damme P et al. Long-term persistence of humoral and cellular immune responses induced by an AS03A-adjuvanted H1N1 2009 influenza vaccine: an open-label, randomized study in adults aged 18-60 years and older. 2013 Hum Vaccin Immunother pmid:23571166
Guan X et al. Immunotherapeutic efficiency of a tetravalent Aβ1-15 vaccine in APP/PS1 transgenic mice as mouse model for Alzheimer's disease. 2013 Hum Vaccin Immunother pmid:23732905
Candela S et al. An early (3-6 weeks) active surveillance study to assess the safety of pandemic influenza vaccine Focetria in a province of Emilia-Romagna region, Italy - part one. 2013 Vaccine pmid:22766247
Dosio F et al. Ruthenium polypyridyl squalene derivative: a novel self-assembling lipophilic probe for cellular imaging. 2013 Int J Pharm pmid:22824513
Ventura R et al. Technology transfer of an oil-in-water vaccine-adjuvant for strengthening pandemic influenza preparedness in Indonesia. 2013 Vaccine pmid:22884665
Moro ML et al. A population based cohort study to assess the safety of pandemic influenza vaccine Focetria in Emilia-Romagna region, Italy - part two. 2013 Vaccine pmid:22885015
Tascon M et al. Determinations of gas-liquid partition coefficients using capillary chromatographic columns. Alkanols in squalane. 2013 J Chromatogr A pmid:23659974
Ito R et al. Purification, kinetics, inhibitors and CD for recombinant β-amyrin synthase from Euphorbia tirucalli L and functional analysis of the DCTA motif, which is highly conserved among oxidosqualene cyclases. 2013 FEBS J. pmid:23294602
Zotos A et al. Effect of baking of sardine (Sardina pilchardus) and frying of anchovy (Engraulis encrasicholus) in olive and sunflower oil on their quality. 2013 Food Sci Technol Int pmid:23239760
O'Hagan DT et al. The history of MF59(®) adjuvant: a phoenix that arose from the ashes. 2013 Expert Rev Vaccines pmid:23256736
Kostyuk VA et al. Modulation of human keratinocyte responses to solar UV by plant polyphenols as a basis for chemoprevention of non-melanoma skin cancers. 2013 Curr. Med. Chem. pmid:23210792
Caron J et al. Improving the antitumor activity of squalenoyl-paclitaxel conjugate nanoassemblies by manipulating the linker between paclitaxel and squalene. 2013 Adv Healthc Mater pmid:23213041
Rubinstein F et al. Influenza A/H1N1 MF59 adjuvanted vaccine in pregnant women and adverse perinatal outcomes: multicentre study. 2013 BMJ pmid:23381200
Puig-Barberà J et al. MF59-adjuvanted and virosomal influenza vaccines for preventing influenza hospitalization in older people: comparative effectiveness using the Valencia health care information system. 2013 Vaccine pmid:23731629
Vriet C et al. From squalene to brassinolide: the steroid metabolic and signaling pathways across the plant kingdom. 2013 Mol Plant pmid:23761349
Gilmore SF et al. Role of squalene in the organization of monolayers derived from lipid extracts of Halobacterium salinarum. 2013 Langmuir pmid:23713788
Okajima M et al. Preparation and physicochemical properties of surfactant-free emulsions using electrolytic-reduction ion water containing lithium magnesium sodium silicate. 2013 Drug Discov Ther pmid:23715508
Hong WK et al. Characterization of a squalene synthase from the thraustochytrid microalga Aurantiochytrium sp. KRS101. 2013 J. Microbiol. Biotechnol. pmid:23676912
Yoshimura T et al. Solution properties and emulsification properties of amino acid-based gemini surfactants derived from cysteine. 2013 J Oleo Sci pmid:23985487
Fu D et al. ATR-IR study of ozone initiated heterogeneous oxidation of squalene in an indoor environment. 2013 Environ. Sci. Technol. pmid:23957297