(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Mouzdahir A et al. | Aerobic and anaerobic abiotic oxidation of squalene in the presence of hydroperoxides. | 2001 | Chemosphere | pmid:11482668 |
Ceruti M et al. | Vinyl sulfide derivatives of truncated oxidosqualene as selective inhibitors of oxidosqualene and squalene-hopene cyclases. | 2001 | Lipids | pmid:11485168 |
Abe I et al. | Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase. | 2001 | J. Nat. Prod. | pmid:11520216 |
Fontana A et al. | Evidence for the biosynthesis of squalene via the methylerythritol phosphate pathway in a Streptomyces sp. obtained from a marine sediment. | 2001 | J. Org. Chem. | pmid:11529755 |
Dupuis M et al. | Immunization with the adjuvant MF59 induces macrophage trafficking and apoptosis. | 2001 | Eur. J. Immunol. | pmid:11592066 |
Rajaratnam RA et al. | Cholesterol absorption, synthesis, and fecal output in postmenopausal women with and without coronary artery disease. | 2001 | Arterioscler. Thromb. Vasc. Biol. | pmid:11597940 |
Gasparini R et al. | Increased immunogenicity of the MF59-adjuvanted influenza vaccine compared to a conventional subunit vaccine in elderly subjects. | 2001 | Eur. J. Epidemiol. | pmid:11599686 |
Davis TA et al. | Idiotype vaccination following ABMT can stimulate specific anti-idiotype immune responses in patients with B-cell lymphoma. | 2001 | Biol. Blood Marrow Transplant. | pmid:11669219 |
McFarland EJ et al. | Human immunodeficiency virus type 1 (HIV-1) gp120-specific antibodies in neonates receiving an HIV-1 recombinant gp120 vaccine. | 2001 | J. Infect. Dis. | pmid:11679925 |
Radwan SS and Mangold HK | Lipids in plant tissue cultures. V. Effect of environmental conditions on the lipids of Glycine soja and Brassica napus cultures. | 1975 | Chem. Phys. Lipids | pmid:1168102 |