(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Albro PW and Fishbein L | Intestinal absorption of polychlorinated biphenyls in rats. | 1972 | Bull Environ Contam Toxicol | pmid:4630020 |
| Rilling HC | The effect of sterol carrier protein on squalene synthesis. | 1972 | Biochem. Biophys. Res. Commun. | pmid:4400440 |
| Gaskin F and Clayton RB | An interstrain difference in cholesterol synthesis in vitro in mice, dependent upon a difference in endogenous NADPH-generating capacity. | 1972 | J. Lipid Res. | pmid:4400581 |
| Ferezou JP et al. | [On the absence of biosynthesis of sterols and squalene in coelenterata (anthozoa), the sea anemone Calliactis parasitica]. | 1972 | Experientia | pmid:4401744 |
| Ferezou JP et al. | [The absence of sterol and squalene biosynthesis a coelenterata (anthozoa), the sea anemone Calliactis parasitica]. | 1972 | Experientia | pmid:4402545 |
| Dugan RE and Porter JW | Hog liver squalene synthetase: the partial purification of the particulate enzyme and kinetic analysis of the reaction. | 1972 | Arch. Biochem. Biophys. | pmid:4403691 |
| Walton MJ and Pennock JF | Some studies on the biosynthesis of ubiguinone, isoprenoid alcohols, squalene and sterols by marine invertebrates. | 1972 | Biochem. J. | pmid:4403925 |
| Qureshi AA et al. | Lycopersene and prelycopersene pyrophosphate. Intermediates in carotene biosynthesis. | 1972 | J. Biol. Chem. | pmid:4403969 |
| Nitchuk WM and Ainsworth L | The de novo synthesis of sterols and cholesterol from acetate-1- 14 C by sheep and pig placental and fetal liver slices in vitro. | 1972 | Steroids | pmid:5028884 |
| Tai HH and Bloch K | Squalene epoxidase of rat liver. | 1972 | J. Biol. Chem. | pmid:5033388 |
| Kramer JK et al. | Structure ditermination of the squalene, dihydrosqualene and tetrahydrosqualene in Halobacterium cutirubrum. | 1972 | Biochim. Biophys. Acta | pmid:5037322 |
| Kushwaha SC et al. | Isolation and identification of dehydrosqualene and C 40 -carotenoid pigments in Halobacterium cutirubrum. | 1972 | Biochim. Biophys. Acta | pmid:5038263 |
| Avigan J et al. | In vitro biosynthesis of lipids, proteins and deoxyribonucleic acid in aortic tissue and in culture aortic cells. | 1972 | Biochim. Biophys. Acta | pmid:5041430 |
| Nicolosi RJ et al. | Lipid accumulation in muscular foci in White Carneau and Show Racer pigeon aortas. | 1972 | Exp. Mol. Pathol. | pmid:5043333 |
| Tronnier H | [Methodological problems in exogenous and endogenous influencing on the skin surface]. | 1972 | Arch Dermatol Forsch | pmid:4265238 |
| Ramsey RB et al. | Distribution of alkanes in normal and atherosclerotic rabbit aortas. | 1972 May-Jun | Atherosclerosis | pmid:5051654 |
| Ritter MC and Dempsey ME | Squalene and sterol carrier protein: structural properties, lipid-binding, and function in cholesterol biosynthesis. | 1973 | Proc. Natl. Acad. Sci. U.S.A. | pmid:4509660 |
| Terakado M et al. | Effects of arsenite on incorporation of mevalonate-2-14C into squalene-14C in rabbit dental pulp. | 1973 | J Nihon Univ Sch Dent | pmid:4517364 |
| Ruzicka L | In the borderland between bioorganic chemistry and biochemistry. | 1973 | Annu. Rev. Biochem. | pmid:4600996 |
| Bose AK and Hungund BL | The role of glycine in the biosynthesis of steroids. | 1973 | Experientia | pmid:4582087 |
| David MH and Kirsop BH | A correlation between oxygen requirements and the products of sterol synthesis in strains of Saccharomyces cerevisiae. | 1973 | J. Gen. Microbiol. | pmid:4584066 |
| Clark RP and Shirley SG | Identification of skin in airborne particulate matter. | 1973 | Nature | pmid:4585846 |
| Johnson RC and Shah SN | Evidence for the participation of two soluble noncatalytic proteins in hepatic microsomal cholesterol synthesis. | 1973 | Biochem. Biophys. Res. Commun. | pmid:4741538 |
| Egwim PO and Kummerow FA | In vitro hepatic cholesterogenesis in rats fed corn oil and fat-free diets. | 1973 | Life Sci. II | pmid:4708203 |
| Bojesen E et al. | Sterol biosynthesis in vitro of rat renal inner medulla. | 1973 | Biochim. Biophys. Acta | pmid:4713153 |
| Shah SN | Regulation of hepatic cholesterol synthesis from mevalonate in suckling and weaned rats. | 1973 | Lipids | pmid:4713377 |
| Phleger CF et al. | Pressure effect on squalene-2,3-oxide cyclization in fish. | 1973 | Comp. Biochem. Physiol., B | pmid:4719990 |
| van Leusden HA et al. | Lack of squalene and lanosterol synthesis by the perfused human placenta at term. | 1973 | J. Steroid Biochem. | pmid:4747979 |
| Farrington JW et al. | Intercalibration of analyses of recently biosynthesized hydrocarbons and petroleum hydrocarbons in marine lipids. | 1973 | Bull Environ Contam Toxicol | pmid:4753263 |
| Murakami S | Isolation and analysis of squalene alcohols from rat preputial glands. | 1973 | Kobe J Med Sci | pmid:4764042 |
| Hellstrom KH et al. | Studies of the in vivo metabolism of mevalonic acid in the normal rat. | 1973 | J. Clin. Invest. | pmid:4703220 |
| Qureshi AA et al. | Squalene synthetase. II. Purification and properties of bakers' yeast enzyme. | 1973 | J. Biol. Chem. | pmid:4348552 |
| Beytia E et al. | Squalene synthetase. 3. Mechanism of the reaction. | 1973 | J. Biol. Chem. | pmid:4348553 |
| Slakey LL et al. | Occurrence of the enzymes effecting the conversion of acetyl CoA to squalene in homogenates of hog aorta. | 1973 | J. Lipid Res. | pmid:4351784 |
| Morris PW and Gorski J | Control of steroidogenesis in pre-ovulatory cells. Luteinizing hormone stimulation of (14C)-acetate incorporation into sterols. | 1973 | J. Biol. Chem. | pmid:4355508 |
| Derksen A and Cohen P | Extensive incorporation of (2-14C) mevalonic acid into cholesterol precursors by human platelets in vitro. | 1973 | J. Biol. Chem. | pmid:4355579 |
| Inomata N | [Symposium I: aging and the activity of the sebaceous glands]. | 1973 | Nihon Hifuka Gakkai Zasshi | pmid:4546667 |
| Faulkner DJ and Petersen MR | Application of the claisen rearrangement to the synthesis of trans trisubstituted olefinic bonds. Synthesis of squalene and insect juvenile hormone. | 1973 | J. Am. Chem. Soc. | pmid:4687674 |
| Caspi E et al. | Mechanism of squalene cyclization: the chiral origin of the C-7 and C-15 hydrogen atoms of fusidic acid. | 1973 | J. Steroid Biochem. | pmid:4795867 |
| Ebersole RC et al. | Mechanism of oxidative cyclization of squalene. Evidence for cyclization of squalene from either end of the squalene molecule in the in vivo biosynthesis of fusidic acid by Fusidium coccineum. | 1973 | J. Am. Chem. Soc. | pmid:4796972 |
| Kellum RE et al. | Human sebaceous gland lipids: in vitro incubations with 14C-labelled compounds. | 1973 | J. Invest. Dermatol. | pmid:4684160 |
| Tabacik C et al. | The squalene epoxidase-cyclase activity of human term placenta. | 1973 | FEBS Lett. | pmid:4747843 |
| Bhavani BR and Short RV | Formation of steroids by the pregnant mare. 3. Metabolism of 14C-squalene and 3H-dehydroisoandrosterone injected into the fetal circulation. | 1973 | Endocrinology | pmid:4267110 |
| Williams M et al. | The effect of local temperature changes on sebum excretion rate and forehead surface lipid composition. | 1973 | Br. J. Dermatol. | pmid:4270005 |
| Gloor M et al. | [Composition of skin surface lipids in persons with seborrhoea sicca and seborrhoea oleosa (author's transl)]. | 1973 | Arch Dermatol Forsch | pmid:4270568 |
| Cunliffe WJ et al. | Tetracycline and acne vulgaris: a clinical and laboratory investigation. | 1973 | Br Med J | pmid:4271323 |
| Cotterill JA et al. | Variation in skin surface lipid composition and sebum excretion rate with time. | 1973 | Acta Derm. Venereol. | pmid:4127454 |
| Voogt PA | Investigations of the capacity of synthesizing 3 beta-sterols in mollusca. X. Biosynthesis and composition of 3 beta-sterols in Cephalopoda. | 1973 | Arch. Int. Physiol. Biochim. | pmid:4127479 |
| Qureshi AA et al. | Biosynthesis of prelycopersene pyrophosphate and lycopersene by squalene synthetase. | 1973 | J. Biol. Chem. | pmid:4144543 |
| Kawaguchi A et al. | Subcellular distribution of sesterterpene- and sterol-biosynthesizing activities in Cochliobolus heterostrophus. | 1973 | Biochim. Biophys. Acta | pmid:4120185 |