(e,e,e,e)-squalene

(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (e,e,e,e)-squalene?

(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene

MeSH term MeSH ID Detail
Acne Vulgaris D000152 35 associated lipids
Adenocarcinoma D000230 166 associated lipids
Alopecia Areata D000506 6 associated lipids
Alzheimer Disease D000544 76 associated lipids
Olfaction Disorders D000857 17 associated lipids
Arteriosclerosis D001161 86 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Body Weight D001835 333 associated lipids
Brain Diseases D001927 27 associated lipids
Celiac Disease D002446 16 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Cholelithiasis D002769 16 associated lipids
Cholestasis D002779 23 associated lipids
Chondrodysplasia Punctata D002806 8 associated lipids
Chronic Disease D002908 7 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Coronary Disease D003327 70 associated lipids
Demyelinating Diseases D003711 15 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Edema D004487 152 associated lipids
Exostoses, Multiple Hereditary D005097 3 associated lipids
Fasciitis D005208 2 associated lipids
Fatigue D005221 10 associated lipids
Fibrosarcoma D005354 8 associated lipids
Gallbladder Diseases D005705 3 associated lipids
Hemolysis D006461 131 associated lipids
Hepatitis D006505 11 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Hyperlipoproteinemia Type III D006952 4 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Inflammation D007249 119 associated lipids
Influenza, Human D007251 11 associated lipids
Keloid D007627 12 associated lipids
Leukemia D007938 74 associated lipids
Leukemia P388 D007941 43 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Leukemia, Hairy Cell D007943 5 associated lipids
Lipodystrophy D008060 4 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Nervous System Diseases D009422 37 associated lipids
Neuroblastoma D009447 66 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with (e,e,e,e)-squalene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (e,e,e,e)-squalene?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (e,e,e,e)-squalene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (e,e,e,e)-squalene

Download all related citations
Per page 10 20 50 100 | Total 1766
Authors Title Published Journal PubMed Link
Malathi P and Ganguly J Studies on metabolism of vitamin A. 8. Effect of ascorbate on isoprenoid metabolism in vitamin A-deficient rats. 1964 Biochem. J. pmid:5837438
GOODMAN DS SQUALENE IN HUMAN AND RAT BLOOD PLASMA. 1964 J. Clin. Invest. pmid:14192529
SALOKANGAS RA et al. TERPENE METABOLISM IN THE RAT TESTIS. I. THE CONVERSION OF ISOPENTENYL PYROPHOSPHATE TO SQUALENE AND STEROLS. 1964 Biochemistry pmid:14211625
MCCARTHY MJ et al. COMPOSITION OF MOLECULAR DISTILLATES OF BUTTER OIL: ISOLATION AND IDENTIFICATION OF COMPONENTS OTHER THAN GLYCERIDES. 1964 J. Lipid Res. pmid:14221107
TSAI SC et al. TESTICULAR STEROLS. 1. INCORPORATION OF MEVALONATE AND ACETATE INTO STEROLS BY TESTICULAR TISSUE FROM RATS. 1964 Arch. Biochem. Biophys. pmid:14186739
VAN DEN OORD A THE ABSENCE OF CHOLESTEROL SYNTHESIS IN THE CRAB, CANCER PAGURUS L. 1964 Comp. Biochem. Physiol. pmid:14246359
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LUCY JA and DINGLE JT FAT-SOLUBLE VITAMINS AND BIOLOGICAL MEMBRANES. 1964 Nature pmid:14222261
Krishna G et al. An enzyme-bound intermediate in the conversion of farnesyl pyrophosphate to squalene. 1964 Biochem. Biophys. Res. Commun. pmid:4284347
Paroli E [Effect of beta-carotene and of squalene on analgesia and respiratory depression caused by morphine]. 1964 Boll. Soc. Ital. Biol. Sper. pmid:5877121