(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Thiele JJ et al. | The antioxidant network of the stratum corneum. | 2001 | Curr. Probl. Dermatol. | pmid:11225199 |
Shibata N et al. | Supernatant protein factor, which stimulates the conversion of squalene to lanosterol, is a cytosolic squalene transfer protein and enhances cholesterol biosynthesis. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11226224 |
Voogt PA et al. | What about squalene in the earthworm Lumbricus terrestris? | 1975 | Comp. Biochem. Physiol., B | pmid:1122731 |
Cunningham CK et al. | Safety of 2 recombinant human immunodeficiency virus type 1 (HIV-1) envelope vaccines in neonates born to HIV-1-infected women. | 2001 | Clin. Infect. Dis. | pmid:11229849 |
Relas H et al. | Acute effect of dietary stanyl ester dose on post-absorptive alpha-tocopherol, beta-carotene, retinol and retinyl palmitate concentrations. | 2001 | Br. J. Nutr. | pmid:11242481 |
Buckner FS et al. | Potent anti-Trypanosoma cruzi activities of oxidosqualene cyclase inhibitors. | 2001 | Antimicrob. Agents Chemother. | pmid:11257036 |
Podda A | The adjuvanted influenza vaccines with novel adjuvants: experience with the MF59-adjuvanted vaccine. | 2001 | Vaccine | pmid:11257408 |
Pregliasco F et al. | Immunogenicity and safety of three commercial influenza vaccines in institutionalized elderly. | 2001 | Aging (Milano) | pmid:11292151 |
Blader IJ et al. | Microarray analysis reveals previously unknown changes in Toxoplasma gondii-infected human cells. | 2001 | J. Biol. Chem. | pmid:11294868 |
Ruiz-Gutiérrez V et al. | Detection of squalene in alpha-fetoprotein and fetal serum albumin from bovine. | 2001 | J. Protein Chem. | pmid:11330344 |