(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Goff PH et al. | Adjuvants and immunization strategies to induce influenza virus hemagglutinin stalk antibodies. | 2013 | PLoS ONE | pmid:24223176 |
Yüzbaşıoğlu D et al. | Genotoxicity assessment of vaccine adjuvant squalene. | 2013 | Food Chem. Toxicol. | pmid:23454296 |
Malmierca MG et al. | Relevance of trichothecenes in fungal physiology: disruption of tri5 in Trichoderma arundinaceum. | 2013 | Fungal Genet. Biol. | pmid:23454546 |
RodrÃguez-López J et al. | Epoxide-opening cascades triggered by a Nicholas reaction: total synthesis of teurilene. | 2013 | Angew. Chem. Int. Ed. Engl. | pmid:23436322 |
Skowronski DM et al. | Re: "effectiveness of adjuvanted influenza vaccination in elderly subjects in northern Italy". | 2013 | Am. J. Epidemiol. | pmid:23436898 |
Kabuto H et al. | Effects of squalene/squalane on dopamine levels, antioxidant enzyme activity, and fatty acid composition in the striatum of Parkinson's disease mouse model. | 2013 | J Oleo Sci | pmid:23357814 |
Vinay TN et al. | Inactivated vaccine against viral hemorrhagic septicemia (VHS) emulsified with squalene and aluminum hydroxide adjuvant provides long term protection in olive flounder (Paralichthys olivaceus). | 2013 | Vaccine | pmid:23896420 |
Ito R et al. | Effect of cation-π interactions and steric bulk on the catalytic action of oxidosqualene cyclase: a case study of Phe728 of β-amyrin synthase from Euphorbia tirucalli L. | 2013 | Chemistry | pmid:24203491 |
Rigane G et al. | Effect of storage on refined olive oil composition: stabilization by addition of chlorophyll pigments and squalene. | 2013 | J Oleo Sci | pmid:24292349 |
Esche R et al. | Online LC-GC-based analysis of minor lipids in various tree nuts and peanuts. | 2013 | J. Agric. Food Chem. | pmid:24251555 |