| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hyperlipoproteinemia Type III | D006952 | 4 associated lipids |
| Coronavirus Infections | D018352 | 4 associated lipids |
| Lipodystrophy | D008060 | 4 associated lipids |
| Viremia | D014766 | 4 associated lipids |
| Tinea Versicolor | D014010 | 5 associated lipids |
| Keratitis, Herpetic | D016849 | 5 associated lipids |
| Leukemia, Hairy Cell | D007943 | 5 associated lipids |
| Parasitemia | D018512 | 5 associated lipids |
| Alopecia Areata | D000506 | 6 associated lipids |
| Chronic Disease | D002908 | 7 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Rontani JF et al. | Aerobic and anaerobic metabolism of squalene by a denitrifying bacterium isolated from marine sediment. | 2002 | Arch. Microbiol. | pmid:12209261 |
| Brasser AJ et al. | Presence of wax esters and squalene in human saliva. | 2011 | Arch. Oral Biol. | pmid:21247555 |
| Tilvis R and Miettinen TA | Squalene, methyl sterol, and cholesterol levels in human organs. Postmortem analysis of their distributions. | 1980 | Arch. Pathol. Lab. Med. | pmid:6892520 |
| Lee KT et al. | Structure of three new terpenoids, spiciformisins a and b, and monocyclosqualene, isolated from the herbs of Ligularia fischeri var. spiciformis and cytotoxicity. | 2002 | Arch. Pharm. Res. | pmid:12510832 |
| Yoo YC et al. | Inhibitory effect of BCG cell-wall skeletons (BCG-CWS) emulsified in squalane on tumor growth and metastasis in mice. | 2002 | Arch. Pharm. Res. | pmid:12214866 |
| Wu J et al. | Superior protection provided by a single dose of MF59-adjuvanted whole inactivated H5N1 influenza vaccine in type 1 diabetic mice. | 2011 | Arch. Virol. | pmid:21110049 |
| Garbuzov AG et al. | [The presence of squalene in the human aorta]. | 1965 | Arkh. Patol. | pmid:5881137 |
| van Himbergen TM et al. | Familial combined hyperlipidemia is associated with alterations in the cholesterol synthesis pathway. | 2010 | Arterioscler. Thromb. Vasc. Biol. | pmid:19834104 |
| Rajaratnam RA et al. | Cholesterol absorption, synthesis, and fecal output in postmenopausal women with and without coronary artery disease. | 2001 | Arterioscler. Thromb. Vasc. Biol. | pmid:11597940 |
| Luan Z et al. | Statins inhibit secretion of metalloproteinases-1, -2, -3, and -9 from vascular smooth muscle cells and macrophages. | 2003 | Arterioscler. Thromb. Vasc. Biol. | pmid:12663370 |