(e,e,e,e)-squalene

(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (e,e,e,e)-squalene?

(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene

MeSH term MeSH ID Detail
Fibrosarcoma D005354 8 associated lipids
Chondrodysplasia Punctata D002806 8 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Fatigue D005221 10 associated lipids
Pregnancy Complications, Infectious D011251 11 associated lipids
Scalp Dermatoses D012536 11 associated lipids
Influenza, Human D007251 11 associated lipids
Hepatitis D006505 11 associated lipids
Otitis Media D010033 12 associated lipids
Dermatitis, Occupational D009783 12 associated lipids
Keloid D007627 12 associated lipids
Rosacea D012393 13 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Demyelinating Diseases D003711 15 associated lipids
Celiac Disease D002446 16 associated lipids
Cholelithiasis D002769 16 associated lipids
Xanthomatosis D014973 17 associated lipids
Olfaction Disorders D000857 17 associated lipids
Periodontitis D010518 22 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Per page 10 20 50 100 | Total 84

PubChem Associated disorders and diseases

What pathways are associated with (e,e,e,e)-squalene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with (e,e,e,e)-squalene?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (e,e,e,e)-squalene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (e,e,e,e)-squalene

Download all related citations
Per page 10 20 50 100 | Total 1766
Authors Title Published Journal PubMed Link
Kelly GS Squalene and its potential clinical uses. 1999 Altern Med Rev pmid:9988781
DICKHART W The squalene contents of various oils. 1955 Am J Pharm Sci Support Public Health pmid:13275573
Miettinen TA et al. Enhanced cholesterol elimination and synthesis related to low-density lipoprotein metabolism. 1987 Am. Heart J. pmid:3812207
Newmark HL Is oleic acid or squalene the important preventive agent? 2000 Am. J. Clin. Nutr. pmid:10919949
Downing DT et al. Changes in skin surface lipid composition induced by severe caloric restriction in man. 1972 Am. J. Clin. Nutr. pmid:5010536
Miettinen TA and Vanhanen H Serum concentration and metabolism of cholesterol during rapeseed oil and squalene feeding. 1994 Am. J. Clin. Nutr. pmid:8310985
Strauss JS et al. Surface lipid composition in children with protein-calorie malnutrition. 1978 Am. J. Clin. Nutr. pmid:414616
Villa M et al. Safety of MF59-adjuvanted influenza vaccination in the elderly: results of a comparative study of MF59-adjuvanted vaccine versus nonadjuvanted influenza vaccine in northern Italy. 2013 Am. J. Epidemiol. pmid:23863759
Mannino S et al. Effectiveness of adjuvanted influenza vaccination in elderly subjects in northern Italy. 2012 Am. J. Epidemiol. pmid:22940713
Skowronski DM et al. Re: "effectiveness of adjuvanted influenza vaccination in elderly subjects in northern Italy". 2013 Am. J. Epidemiol. pmid:23436898