(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hoshino T et al. | β-Amyrin biosynthesis: the critical role of steric volume at C-19 of 2,3-oxidosqualene for its correct folding to generate the pentacyclic scaffold. | 2014 | Org. Lett. | pmid:24960408 |
Ali HM et al. | Effects of silencing the RET/PTC1 oncogene in papillary thyroid carcinoma by siRNA-squalene nanoparticles with and without fusogenic companion GALA-cholesterol. | 2014 | Thyroid | pmid:23885719 |
Wołosik K et al. | The importance and perspective of plant-based squalene in cosmetology. | 2013 Jan-Feb | J Cosmet Sci | pmid:23449131 |
Naughton C et al. | Transcription forms and remodels supercoiling domains unfolding large-scale chromatin structures. | 2013 | Nat. Struct. Mol. Biol. | pmid:23416946 |
Naziri E and Tsimidou MZ | Formulated squalene for food related applications. | 2013 | Recent Pat Food Nutr Agric | pmid:23270393 |
Wijnans L et al. | Effectiveness of MF59â„¢ adjuvanted influenza A(H1N1)pdm09 vaccine in risk groups in the Netherlands. | 2013 | PLoS ONE | pmid:23646191 |
Gavaldà J et al. | Immunogenicity of pandemic influenza A H1N1/2009 adjuvanted vaccine in pediatric solid organ transplant recipients. | 2013 | Pediatr Transplant | pmid:23692602 |
Hillaireau H et al. | Anti-HIV efficacy and biodistribution of nucleoside reverse transcriptase inhibitors delivered as squalenoylated prodrug nanoassemblies. | 2013 | Biomaterials | pmid:23562054 |
Vera-Lastra O et al. | Autoimmune/inflammatory syndrome induced by adjuvants (Shoenfeld's syndrome): clinical and immunological spectrum. | 2013 | Expert Rev Clin Immunol | pmid:23557271 |
AÄimoviÄ J and Rozman D | Steroidal triterpenes of cholesterol synthesis. | 2013 | Molecules | pmid:23558541 |