| MeSH term | MeSH ID | Detail |
|---|---|---|
| Weight Gain | D015430 | 101 associated lipids |
| Brain Diseases | D001927 | 27 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Leukemia P388 | D007941 | 43 associated lipids |
| Metabolism, Inborn Errors | D008661 | 46 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Thyroid Neoplasms | D013964 | 33 associated lipids |
| Fibrosarcoma | D005354 | 8 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Demyelinating Diseases | D003711 | 15 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Cholestasis | D002779 | 23 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Nervous System Diseases | D009422 | 37 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Candela S et al. | An early (3-6 weeks) active surveillance study to assess the safety of pandemic influenza vaccine Focetria in a province of Emilia-Romagna region, Italy - part one. | 2013 | Vaccine | pmid:22766247 |
| Dosio F et al. | Ruthenium polypyridyl squalene derivative: a novel self-assembling lipophilic probe for cellular imaging. | 2013 | Int J Pharm | pmid:22824513 |
| Ventura R et al. | Technology transfer of an oil-in-water vaccine-adjuvant for strengthening pandemic influenza preparedness in Indonesia. | 2013 | Vaccine | pmid:22884665 |
| O'Hagan DT et al. | The history of MF59(®) adjuvant: a phoenix that arose from the ashes. | 2013 | Expert Rev Vaccines | pmid:23256736 |
| Kostyuk VA et al. | Modulation of human keratinocyte responses to solar UV by plant polyphenols as a basis for chemoprevention of non-melanoma skin cancers. | 2013 | Curr. Med. Chem. | pmid:23210792 |
| Caron J et al. | Improving the antitumor activity of squalenoyl-paclitaxel conjugate nanoassemblies by manipulating the linker between paclitaxel and squalene. | 2013 | Adv Healthc Mater | pmid:23213041 |
| Vriet C et al. | From squalene to brassinolide: the steroid metabolic and signaling pathways across the plant kingdom. | 2013 | Mol Plant | pmid:23761349 |
| Gilmore SF et al. | Role of squalene in the organization of monolayers derived from lipid extracts of Halobacterium salinarum. | 2013 | Langmuir | pmid:23713788 |
| Okajima M et al. | Preparation and physicochemical properties of surfactant-free emulsions using electrolytic-reduction ion water containing lithium magnesium sodium silicate. | 2013 | Drug Discov Ther | pmid:23715508 |
| Hong WK et al. | Characterization of a squalene synthase from the thraustochytrid microalga Aurantiochytrium sp. KRS101. | 2013 | J. Microbiol. Biotechnol. | pmid:23676912 |