(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yamada Y et al. | Oxidation of acyclic terpenoids by Corynebacterium sp. | 1985 | Appl. Environ. Microbiol. | pmid:4004225 |
| Rontani JF et al. | Production of a polyunsaturated isoprenoid wax ester during aerobic metabolism of squalene by Marinobacter squalenivorans sp. nov. | 2003 | Appl. Environ. Microbiol. | pmid:12839795 |
| Berekaa MM and Steinbüchel A | Microbial degradation of the multiply branched alkane 2,6,10,15,19, 23-hexamethyltetracosane (Squalane) by Mycobacterium fortuitum and Mycobacterium ratisbonense. | 2000 | Appl. Environ. Microbiol. | pmid:11010899 |
| Siedenburg G and Jendrossek D | Squalene-hopene cyclases. | 2011 | Appl. Environ. Microbiol. | pmid:21531832 |
| Ghimire GP et al. | Improved squalene production via modulation of the methylerythritol 4-phosphate pathway and heterologous expression of genes from Streptomyces peucetius ATCC 27952 in Escherichia coli. | 2009 | Appl. Environ. Microbiol. | pmid:19767465 |
| Tokuhiro K et al. | Overproduction of geranylgeraniol by metabolically engineered Saccharomyces cerevisiae. | 2009 | Appl. Environ. Microbiol. | pmid:19592534 |
| Kamimura N et al. | Construction of squalene-accumulating Saccharomyces cerevisiae mutants by gene disruption through homologous recombination. | 1994 | Appl. Microbiol. Biotechnol. | pmid:7765777 |
| Chang MH et al. | The isolation and characterization of Pseudozyma sp. JCC 207, a novel producer of squalene. | 2008 | Appl. Microbiol. Biotechnol. | pmid:18299826 |
| Short RV | The synthesis and secretion of steroids by the corpus luteum. | 1967 | Arch Anat Microsc Morphol Exp | pmid:4973334 |
| Kellum RE | Human sebaceous gland lipids. Analysis by thin-layer chromatography. | 1967 | Arch Dermatol | pmid:6019001 |