(e,e,e,e)-squalene

(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (e,e,e,e)-squalene?

(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene

MeSH term MeSH ID Detail
Niemann-Pick Diseases D009542 25 associated lipids
Hyperlipoproteinemia Type III D006952 4 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Parkinson Disease D010300 53 associated lipids
Celiac Disease D002446 16 associated lipids
Keloid D007627 12 associated lipids
Influenza, Human D007251 11 associated lipids
Leukemia, Hairy Cell D007943 5 associated lipids
Gallbladder Diseases D005705 3 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Xanthomatosis D014973 17 associated lipids
Atherosclerosis D050197 85 associated lipids
Ossification, Heterotopic D009999 2 associated lipids
Fatigue D005221 10 associated lipids
Keratitis, Herpetic D016849 5 associated lipids
Rosacea D012393 13 associated lipids
Parasitemia D018512 5 associated lipids
Lipodystrophy D008060 4 associated lipids
Exostoses, Multiple Hereditary D005097 3 associated lipids
Tinea Versicolor D014010 5 associated lipids
Parvoviridae Infections D010322 4 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Chronic Disease D002908 7 associated lipids
Simian Acquired Immunodeficiency Syndrome D016097 4 associated lipids
Coronavirus Infections D018352 4 associated lipids
Viremia D014766 4 associated lipids
Alopecia Areata D000506 6 associated lipids
Scalp Dermatoses D012536 11 associated lipids
Fasciitis D005208 2 associated lipids
Pneumonia, Lipid D011017 2 associated lipids
Persian Gulf Syndrome D018923 1 associated lipids
Steatorrhea D045602 2 associated lipids
Hemorrhagic Septicemia, Viral D031941 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with (e,e,e,e)-squalene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (e,e,e,e)-squalene?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (e,e,e,e)-squalene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (e,e,e,e)-squalene

Download all related citations
Per page 10 20 50 100 | Total 1766
Authors Title Published Journal PubMed Link
KARLSON P [NOBEL PRIZE FOR MEDICINE AND PHYSIOLOGY IN 1964]. 1965 Dtsch. Med. Wochenschr. pmid:14238764
CORNFORTH JW et al. THE MIGRATION AND ELIMINATION OF HYDROGEN DURING BIOSYNTHESIS OF CHOLESTEROL FROM SQUALENE. 1965 J. Am. Chem. Soc. pmid:14329430
DIPLOCK AT et al. VITAMIN A AND ISOPRENOID SYNTHESIS IN THE RAT. 1965 Biochem. J. pmid:14333548
VROMAN HE and BAKER GL LIMITS OF DETECTION OF SOME LIPIDS IN THIN-LAYER CHROMATOGRAPHY. 1965 J. Chromatogr. pmid:14334204
GOSSELIN L and DUVIVIER J [BIOSYNTHESIS OF FARNESOL PYROPHOSPHATE AND SQUALENE FROM 2-C14-MEVALONIC ACID BY CELL FRACTIONS OF ADRENAL HOMOGENATE]. 1965 Bull. Soc. Chim. Biol. pmid:14337120
GOODWIN TW and WILLIAMS RJ A MECHANISM FOR THE CYCLIZATION OF AN ACYCLIC PRECURSOR TO FORM BETA-CAROTENE. 1965 Biochem. J. pmid:14342248
SHORB MS et al. EFFECT OF TRIPARANOL ON SYNTHESIS OF SQUALENE AND TETRAHYMANOL BY TETRAHYMENA PYRIFORMIS. 1965 Proc. Soc. Exp. Biol. Med. pmid:14277681
Stone KJ and Hemming FW The incorporation of [2-14C, 4R-3H1] mevalonate and [2-14C, 4S-3H1] mevalonate into squalene, ubiquinone and ergosterol of Aspergillus fumigatus Fresenius. 1965 Biochem. J. pmid:4284430
Garbuzov AG et al. [The presence of squalene in the human aorta]. 1965 Arkh. Patol. pmid:5881137
Goodwin TW and Williams RJ A mechanism for the biosynthesis of alpha-carotene. 1965 Biochem. J. pmid:5881648