(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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WOOTTON JM and WRIGHT LD | Biosynthesis of squalene by the annelid Lumbricus terrestris. | 1960 | Nature | pmid:13786660 |
GOODMAN DS and POPJAK G | Studies on the biosynthesis of cholesterol. XII. Synthesis of allyl pyrophosphates from mevalonate and their conversion into squalene with liver enzymes. | 1960 | J. Lipid Res. | pmid:13851061 |
PATTERSON JF | Biosynthesis of squalene by rat preputial gland. | 1960 | Proc. Soc. Exp. Biol. Med. | pmid:13733368 |
SCHOEN H and FAHSOLD W | [Studies on the problem of resorption of squalene]. | 1960 | Klin. Wochenschr. | pmid:14443328 |
MELCHIORRI-SANTOLINI U and RENZINI G | [Detection of sterols and squalene in sporigenic bacteria]. | 1960 Nov-Dec | Nuovi Ann Ig Microbiol | pmid:13769177 |
RENZINI G | [Detection of sterols and squalene in B. coli aerogenes]. | 1960 Nov-Dec | Nuovi Ann Ig Microbiol | pmid:13740904 |
GAYLOR JL | Anaerobic conversion of acetate to squalene by rat skin. | 1961 | Proc. Soc. Exp. Biol. Med. | pmid:13704081 |
GOODMAN DS | Studies on the conversion of squalene to sterol with rat liver enzymes. | 1961 | J. Biol. Chem. | pmid:13707027 |
GOSSELIN L and PODBER-WAGNER E | [New observations on the particles interfering in the biosynthesis of squalene from mevalonic acid]. | 1961 | Arch. Int. Physiol. Biochim. | pmid:13707370 |
SEDEE PD | Intermediary metabolism in aseptically reared blowfly larvae, Calliphora erythrocephala (Meig.). I. Buosynthesis of squalene and cholesterol. | 1961 | Arch. Int. Physiol. Biochim. | pmid:13749584 |