| MeSH term | MeSH ID | Detail |
|---|---|---|
| Pain | D010146 | 64 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Coronary Artery Disease | D003324 | 47 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Metabolism, Inborn Errors | D008661 | 46 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Leukemia P388 | D007941 | 43 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Douglas TJ et al. | Inhibition of cholesterol biosynthesis in ovine ovarian follicles in vitro by human chorionic gonadotrophin. | 1978 | Aust. J. Biol. Sci. | pmid:571711 |
| Mukherjee S and Bhose A | Studies on estrogen regulation of cholesterol biosynthesis in rat liver microsomes. | 1968 | Biochim. Biophys. Acta | pmid:5721032 |
| Threlfall DR et al. | Biosynthesis of phytoquinones. Incorporation of L-[Me-14C,3H]methionine into terpenoid quinones and chromanols in maize shoots. | 1968 | Biochem. J. | pmid:5721452 |
| Autrum H et al. | [Squalene in the glandular secretion of mammals]. | 1968 | Naturwissenschaften | pmid:5726004 |
| Scharf SS and Simpson KL | Attempts to detect lycopersene formation in yeast. | 1968 | Biochem. J. | pmid:5753091 |
| Porcellati G and Giorgini D | The effect of alpha-methyl gamma-phenyl butyric acid on sterol biosynthesis in vitro. | 1969 | Biochem. Pharmacol. | pmid:5772592 |
| Goad LJ and Goodwin TW | Studies in phytosterol biosynthesis: observations on the biosynthesis of fucosterol in the marine brown alga Fucus spiralis. | 1969 | Eur. J. Biochem. | pmid:5780485 |
| Eppenberger U et al. | [Anerobic cyclization of squalen-2,3-epoxide to cycloartenol in Nicotiana tabacum L. tissue cultures]. | 1969 | Eur. J. Biochem. | pmid:5781271 |
| Ikekawa N et al. | Determination of morphine in urine by gas chromatography. | 1969 | Anal. Biochem. | pmid:5781407 |
| Akhtar M et al. | The role of a cholesta-8,14-dien-3-beta-ol system in cholesterol biosynthesis. | 1969 | Biochem. J. | pmid:5783476 |
| Tornabene TG et al. | Occurrence of squalene, di- and tetrahydrosqualenes, and vitamin MK8 in an extremely halophilic bacterium, Halobacterium cutirubrun. | 1969 | J. Lipid Res. | pmid:5785002 |
| Porcellati G et al. | Inhibition of cholesterol synthesis by beta-benzal butyric acid and derivatives. | 1969 | Lipids | pmid:5785689 |
| Boyd GS and Onajobi FD | Control of cholesterol biosynthesis by a plasma apo-lipoprotein. | 1969 | Nature | pmid:5789314 |
| Witiak DT et al. | Inhibition of cholesterolgenesis in vitro by chlorophenoxyacetic acids. Effect of alpha-methyl groups. | 1969 | J. Med. Chem. | pmid:5793168 |
| Rees HH et al. | 2,3-oxidosqualene cycloartenol cyclase from Ochromonas malhamensis. | 1969 | Biochim. Biophys. Acta | pmid:5797101 |
| Walton TJ et al. | Biosynthesis of xanthophylls in higher plants: stereochemistry of hydroxylation at C-3. | 1969 | Biochem. J. | pmid:5801311 |
| Miettinen TA | Serum squalene and methyl sterols as indicators of cholesterol synthesis in vivo. | 1969 | Life Sci. | pmid:5801489 |
| Foti L et al. | Biosynthesis of cholesterol from long-chain fatty acids in cell-free systems from rat liver. | 1969 | Life Sci. | pmid:5804653 |
| Yamamoto S and Bloch K | On the enzymes catalysing the transformation of squalene to lanosterol. | 1969 | Biochem. J. | pmid:5807185 |
| Higgins MJ and Kekwick RG | The role of malonyl-coenzyme A in isoprenoid biosynthesis. | 1969 | Biochem. J. | pmid:5807201 |
| Malathi P and Ganguly J | Studies on metabolism of vitamin A. 8. Effect of ascorbate on isoprenoid metabolism in vitamin A-deficient rats. | 1964 | Biochem. J. | pmid:5837438 |
| Van Leusden H and Villee CA | The de novo synthesis of sterols and steroids from acetate by preparations of human term placenta. | 1965 | Steroids | pmid:5857495 |
| Kipping D | [Observations on skin surface fats]. | 1965 | Z Haut Geschlechtskr | pmid:5860995 |
| Paroli E | [Effect of beta-carotene and of squalene on analgesia and respiratory depression caused by morphine]. | 1964 | Boll. Soc. Ital. Biol. Sper. | pmid:5877121 |
| Garbuzov AG et al. | [The presence of squalene in the human aorta]. | 1965 | Arkh. Patol. | pmid:5881137 |
| Goodwin TW and Williams RJ | A mechanism for the biosynthesis of alpha-carotene. | 1965 | Biochem. J. | pmid:5881648 |
| Cory EJ et al. | 2,3-oxidosqualene, an intermediate in the biological synthesis of sterols from squalene. | 1966 | J. Am. Chem. Soc. | pmid:5918046 |
| Corey EJ and Russey WE | Metabolic fate of 10,11-dihydrosqualene in sterol-producing rat liver homogenate. | 1966 | J. Am. Chem. Soc. | pmid:5918047 |
| Van Tamelen EE et al. | Enzymic conversion of squalene 2,3-oxide to lanosterol and cholesterol. | 1966 | J. Am. Chem. Soc. | pmid:5918048 |
| Cmelik SH and Webster GD | Squalene in vernix caseosa from African neonates. | 1966 | Cent Afr J Med | pmid:5919884 |
| Hsia SL et al. | Lipid metabolism in human skin. I. Lipogenesis from acetate-1-14C. | 1966 | J. Invest. Dermatol. | pmid:5924299 |
| Butterworth PH et al. | In vivo incorporation of [2-14-C]-mevalonate into dolichol of rabbit and pig liver. | 1966 | Arch. Biochem. Biophys. | pmid:5944963 |
| Ismail AA et al. | Interrelation between thyroid hormones and essential fatty acids. | 1966 | Acta Physiol Acad Sci Hung | pmid:5953398 |
| Zelewski L and Villee CA | The biosynthesis of squalene, lanosterol, and cholesterol by minced human placenta. | 1966 | Biochemistry | pmid:5963423 |
| Paoletti P et al. | Lipid biosynthesis from labelled precursors in an experimental brain tumor-bearing mouse. | 1966 | Neurochirurgia (Stuttg) | pmid:5966653 |
| Williams RJ et al. | A possible mechanism for the biosynthesis of eschscholtzxanthin. | 1966 | Biochim. Biophys. Acta | pmid:5966716 |
| Chesterton CJ | The subcellular site of cholesterol synthesis in rat liver. | 1966 | Biochem. Biophys. Res. Commun. | pmid:5971766 |
| Brooks CJ et al. | Squalene, 26-hydroxycholesterol and 7-ketocholesterol in human atheromatous plaques. | 1966 | Biochim. Biophys. Acta | pmid:5973204 |
| Van Tamelen EE et al. | Nonenzymic laboratory cyclization of squalene 2,3-oxide. | 1966 | J. Am. Chem. Soc. | pmid:5980879 |
| Wiss O and Wiss V | The influence of fasting on the synthesis of cholesterol, squalene, fatty acids, and ubiquinones in liver, small intestine, and kidney of rats in vivo. | 1977 | Helv. Chim. Acta | pmid:599042 |
| Wiss O and Wiss V | On the influence of cholesterol feeding and of a lipogenic diet on the cholesterogenesis in rat liver in vivo. | 1977 | Helv. Chim. Acta | pmid:599043 |
| Cherkes AI and Klebanov BM | [Cholesterine synthesis as an object of the action of drugs. (Review of the literature)]. | 1966 Nov-Dec | Farmakol Toksikol | pmid:6000378 |
| Hellig HR and Savard K | Sterol biosynthesis in the bovine corpus luteum in vitro. | 1966 | Biochemistry | pmid:6006805 |
| Katsuki H and Bloch K | Studies on the biosynthesis of ergosterol in yeast. Formation of methylated intermediates. | 1967 | J. Biol. Chem. | pmid:6016607 |
| Kellum RE | Human sebaceous gland lipids. Analysis by thin-layer chromatography. | 1967 | Arch Dermatol | pmid:6019001 |
| Matschiner JT et al. | Effect of indigestible oils on vitamin K deficiency in the rat. | 1967 | J. Nutr. | pmid:6021812 |
| Matschiner JT et al. | Mechanism of the effect of retinoic acid and squalene on vitamin K deficiency in the rat. | 1967 | J. Nutr. | pmid:6021953 |
| Kellum RE | Short chain fatty acids (below C12) of human skin surface lipids. | 1967 | J. Invest. Dermatol. | pmid:6022603 |
| Dean PD et al. | A soluble 2,3-oxidosqualene sterol cyclase. | 1967 | J. Biol. Chem. | pmid:6027261 |
| Rao KS and Olson RE | The effect of exogenous cholesterol on the synthesis in vivo of cholesterol, ubiquinone, and squalene in rat liver. | 1967 | Biochem. Biophys. Res. Commun. | pmid:6030977 |