| MeSH term | MeSH ID | Detail |
|---|---|---|
| Pain | D010146 | 64 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Coronary Artery Disease | D003324 | 47 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Metabolism, Inborn Errors | D008661 | 46 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Leukemia P388 | D007941 | 43 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Amdur BH et al. | Presence of squalene in gram-positive bacteria. | 1978 | J. Bacteriol. | pmid:670148 |
| Gavey KL and Scallen TJ | Studies on the conversion of enzymatically generated, microsome-bound squalene to sterol. | 1978 | J. Biol. Chem. | pmid:670211 |
| Wysocki SJ et al. | Simultaneous assessment of fetal lung maturity and sebaceous gland function by gas chromatography. | 1984 | Clin. Chim. Acta | pmid:6705230 |
| Uotani J | [The changes of sterol in lenses]. | 1984 | Nippon Ganka Gakkai Zasshi | pmid:6711397 |
| Salvioli G et al. | Relationships between squalene and cholesterol in bile: effect of ursodeoxycholic acid administration in patients with radiolucent gallstones. | 1984 | Metab. Clin. Exp. | pmid:6738365 |
| Buttke TM and Pyle AL | Effects of unsaturated fatty acid deprivation on neutral lipid synthesis in Saccharomyces cerevisiae. | 1982 | J. Bacteriol. | pmid:6752117 |
| Hata S et al. | Effect of detergents on sterol synthesis in a cell-free system of yeast. | 1982 | J. Lipid Res. | pmid:6752317 |
| Miettinen TA | Phytosterolaemia, xanthomatosis and premature atherosclerotic arterial disease: a case with high plant sterol absorption, impaired sterol elimination and low cholesterol synthesis. | 1980 | Eur. J. Clin. Invest. | pmid:6768564 |
| Bouvier P et al. | Non-specific biosynthesis of gammacerane derivatives by a cell-free system from the protozoon Tetrahymena pyriformis. Conformations of squalene, (3S)-squalene epoxide and (3R)-squalene epoxide during the cyclization. | 1980 | Eur. J. Biochem. | pmid:6780347 |
| Rohmer M et al. | Non-specific lanosterol and hopanoid biosynthesis be a cell-free system from the bacterium Methylococcus capsulatus. | 1980 | Eur. J. Biochem. | pmid:6780348 |
| Yamanishi Y et al. | Serum squalene levels in hepatobiliary diseases. | 1978 | Clin. Chim. Acta | pmid:679482 |
| Kling D and Gamble W | Cholesterol biosynthesis in polychlorinated biphenyl-treated rats. | 1982 | Environ. Res. | pmid:6802634 |
| Schroepfer GJ | Sterol biosynthesis. | 1982 | Annu. Rev. Biochem. | pmid:6810750 |
| Pasechnik VI | [Cooperative analysis of measurements of capacity and optical parameters of bilayer lipid membranes]. | 1983 Jan-Feb | Biofizika | pmid:6830905 |
| Tilvis RS and Miettinen TA | Dietary squalene increases tissue sterols and fecal bile acids in the rat. | 1983 | Lipids | pmid:6835033 |
| Crilly JF and Earnshaw JC | Photon correlation spectroscopy of bilayer lipid membranes. | 1983 | Biophys. J. | pmid:6838962 |
| Fuks-Holmberg D and Bloch K | Intermembrane transfer of squalene promoted by supernatant protein factor. | 1983 | J. Lipid Res. | pmid:6854149 |
| Tilvis RS and Miettinen TA | Absorption and metabolic fate of dietary 3H-squalene in the rat. | 1983 | Lipids | pmid:6855483 |
| Tanio Y et al. | Regression of line-10 hepatocarcinoma with synthetic quinonyl muramyl dipeptide in strain-2 guinea pigs. | 1983 | Gan | pmid:6862142 |
| Ohkuma T et al. | Intensification of host's immunity by squalene in sarcoma 180 bearing ICR mice. | 1983 | J. Pharmacobio-dyn. | pmid:6864440 |
| Hérodin F and Dormont D | [Comparative kinetics of spleen cell-mediated antibody-dependent cytotoxic activity in mice treated with BCG or Mycobacterium smegmatis]. | 1983 Mar-Apr | Ann. Immunol. (Paris) | pmid:6870194 |
| Palamarchuk VI et al. | [Content of squalene and sterols in tissues of the hemopoietic system in normal rats and in experimental leukemia]. | 1983 May-Jun | Vopr. Med. Khim. | pmid:6880121 |
| Kudchodkar BJ et al. | Mechanisms of hypolipidemic action of nicotinic acid. | 1978 | Clin. Pharmacol. Ther. | pmid:688728 |
| Tilvis R and Miettinen TA | Squalene, methyl sterol, and cholesterol levels in human organs. Postmortem analysis of their distributions. | 1980 | Arch. Pathol. Lab. Med. | pmid:6892520 |
| Lapointe JY and Laprade R | Kinetics of carrier-mediated ion transport in two new types of solvent-free lipid bilayers. | 1982 | Biophys. J. | pmid:6896832 |
| Tornabene TG | Non-aerated cultivation of Halobacterium cutirubrum and its effect on cellular squalenes. | 1978 | J. Mol. Evol. | pmid:691076 |
| Tornabene TG et al. | Phytanyl-glycerol ethers and squalenes in the archaebacterium Methanobacterium thermoautotrophicum. | 1978 | J. Mol. Evol. | pmid:691077 |
| Moroyama T | [Sterol metabolism of cultured skin tissue of chick embryo and the effect of anticholesterolemic drugs and chemical carcinogens on it (author's transl)]. | 1981 | Hiroshima Daigaku Shigaku Zasshi | pmid:6953141 |
| Jenkins DT et al. | Amniotic fluid squalene: a useful test in prolonged pregnancy. | 1982 | Aust N Z J Obstet Gynaecol | pmid:6959611 |
| Yoshino K and Matsuo I | [Squalene peroxide formation by UVA irradiation with or without 8-MOP (author's transl)]. | 1981 | Nihon Hifuka Gakkai Zasshi | pmid:6971356 |
| Torinuki W et al. | [Emission spectral analysis of ultraweak chemiluminescence from linolenic acid and squalene peroxides (author's transl)]. | 1982 | Nihon Hifuka Gakkai Zasshi | pmid:6978954 |
| White SH | Formation of "solvent-free" black lipid bilayer membranes from glyceryl monooleate dispersed in squalene. | 1978 | Biophys. J. | pmid:698340 |
| Yarkoni E and Rapp HJ | Influence of type of oil and surfactant concentration on the efficacy of emulsified Mycobacterium bovis BCG cell walls to induce tumor regression in guinea pigs. | 1980 | Infect. Immun. | pmid:6995325 |
| Schroepfer GJ | Sterol biosynthesis. | 1981 | Annu. Rev. Biochem. | pmid:7023367 |
| Masuda A et al. | Potentiation of antifungal effect of amphotericin B by squalene, an intermediate for sterol biosynthesis. | 1982 | J. Antibiot. | pmid:7042672 |
| Takatsuji H et al. | Formation of dehydrosqualene catalyzed by squalene synthetase in Saccharomyces cerevisiae. | 1982 | J. Biochem. | pmid:7042703 |
| Bach D and Miller IR | Glyceryl monooleate black lipid membranes obtained from squalene solutions. | 1980 | Biophys. J. | pmid:7053057 |
| Pratt HP | Preimplantation mouse embryos synthesize membrane sterols. | 1982 | Dev. Biol. | pmid:7054002 |
| Tilvis RS et al. | Lipid composition of bile and gallbladder mucosa in patients with acalculous cholesterolosis. | 1982 | Gastroenterology | pmid:7060883 |
| Richter E et al. | Effects of dietary paraffin, squalane and sucrose polyester on residue disposition and elimination of hexachlorobenzene in rats. | 1982 | Chem. Biol. Interact. | pmid:7083398 |
| Messeri G et al. | Amniotic fluid squalene and gestational age. | 1982 | Clin. Chem. | pmid:7094305 |
| Richter E and Schäfer SG | Effect of squalane on hexachlorobenzene (HCB) concentrations in tissues of mice. | 1982 | J Environ Sci Health B | pmid:7096897 |
| Richter E and Schäfer SG | The effect of squalane on the absorption of dietary cholesterol by the rat. | 1982 | Res Exp Med (Berl) | pmid:7100640 |
| Torinuki W et al. | Effect of beta-carotene on ultraweak chemiluminescence of UVB-irradiated squalene. | 1982 | Tohoku J. Exp. Med. | pmid:7101278 |
| Tiffany JM | Individual variations in human meibomian lipid composition. | 1978 | Exp. Eye Res. | pmid:710541 |
| Tilvis R et al. | Metabolism of squalene in human fat cells. Demonstration of a two-pool system. | 1982 | J. Biol. Chem. | pmid:7107606 |
| Morin RJ et al. | Effect of age and cholestyramine feeding on rat liver 3-hydroxy-3-methyl glutaryl CoA reductase, sterol carrier protein 1 and sterol carrier protein 2 activities. | 1982 | Lipids | pmid:7121212 |
| Saudek CD et al. | Plasma squalene: lipoprotein distribution and kinetic analysis. | 1978 | J. Lipid Res. | pmid:712242 |
| Dillard CJ et al. | Lipid peroxidation during chronic inflammation induced in rats by Freund's adjuvant: effect of vitamin E as measured by expired pentane. | 1982 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:7122999 |
| Tilvis RS and Miettinen TA | Fate of intravenously administered squalene in the rat. | 1982 | Biochim. Biophys. Acta | pmid:7126611 |