(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Xue Z et al. | Divergent evolution of oxidosqualene cyclases in plants. | 2012 | New Phytol. | pmid:22150097 |
Oral E et al. | A new mechanism of oxidation in ultrahigh molecular weight polyethylene caused by squalene absorption. | 2012 | J. Biomed. Mater. Res. Part B Appl. Biomater. | pmid:22190411 |
Sancho A et al. | More on influenza vaccine in young children. | 2012 | N. Engl. J. Med. | pmid:22738111 |
Dell'Era L et al. | Immunogenicity, safety and tolerability of MF59-adjuvanted seasonal influenza vaccine in children with juvenile idiopathic arthritis. | 2012 | Vaccine | pmid:22138210 |
Allain V et al. | Self-assembled nucleolipids: from supramolecular structure to soft nucleic acid and drug delivery devices. | 2012 | Nucleic Acids Res. | pmid:22075995 |
Kim SK and Karadeniz F | Biological importance and applications of squalene and squalane. | 2012 | Adv. Food Nutr. Res. | pmid:22361190 |
Dey AK et al. | Use of a polyanionic carbomer, Carbopol971P, in combination with MF59, improves antibody responses to HIV-1 envelope glycoprotein. | 2012 | Vaccine | pmid:22366638 |
Garçon N et al. | Development and evaluation of AS03, an Adjuvant System containing α-tocopherol and squalene in an oil-in-water emulsion. | 2012 | Expert Rev Vaccines | pmid:22380826 |
RamÃrez-Torres A et al. | Proteomics and gene expression analyses of mitochondria from squalene-treated apoE-deficient mice identify short-chain specific acyl-CoA dehydrogenase changes associated with fatty liver amelioration. | 2012 | J Proteomics | pmid:22402057 |
Liu Y et al. | [Researches on influence of squalene synthase gene polymorphism on catalytic efficiency of its encode enzyme in Glycyrrhiza uralensis]. | 2012 | Zhongguo Zhong Yao Za Zhi | pmid:23627178 |