(e,e,e,e)-squalene

(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (e,e,e,e)-squalene?

(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene

MeSH term MeSH ID Detail
Cholestasis D002779 23 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Niemann-Pick Diseases D009542 25 associated lipids
Brain Diseases D001927 27 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Acne Vulgaris D000152 35 associated lipids
Nervous System Diseases D009422 37 associated lipids
Arthritis D001168 41 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Occupational Diseases D009784 42 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Leukemia P388 D007941 43 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Psoriasis D011565 47 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Per page 10 20 50 100 | Total 84

PubChem Associated disorders and diseases

What pathways are associated with (e,e,e,e)-squalene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with (e,e,e,e)-squalene?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (e,e,e,e)-squalene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (e,e,e,e)-squalene

Download all related citations
Per page 10 20 50 100 | Total 1766
Authors Title Published Journal PubMed Link
Nguyen HT et al. Molecular characterization of Glycine max squalene synthase genes in seed phytosterol biosynthesis. 2013 Plant Physiol. Biochem. pmid:24036394
Borchman D et al. Confirmation of the presence of squalene in human eyelid lipid by heteronuclear single quantum correlation spectroscopy. 2013 Lipids pmid:24081494
Lepeltier E et al. Self-assembly of squalene-based nucleolipids: relating the chemical structure of the bioconjugates to the architecture of the nanoparticles. 2013 Langmuir pmid:24219056
Vono M et al. The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination. 2013 Proc. Natl. Acad. Sci. U.S.A. pmid:24324152
Pannkuk EL et al. Sebaceous lipid profiling of bat integumentary tissues: quantitative analysis of free Fatty acids, monoacylglycerides, squalene, and sterols. 2013 Chem. Biodivers. pmid:24327437
Tegenge MA and Mitkus RJ A physiologically-based pharmacokinetic (PBPK) model of squalene-containing adjuvant in human vaccines. 2013 J Pharmacokinet Pharmacodyn pmid:23912214
Malmierca MG et al. Relevance of trichothecenes in fungal physiology: disruption of tri5 in Trichoderma arundinaceum. 2013 Fungal Genet. Biol. pmid:23454546
Rodríguez-López J et al. Epoxide-opening cascades triggered by a Nicholas reaction: total synthesis of teurilene. 2013 Angew. Chem. Int. Ed. Engl. pmid:23436322
Skowronski DM et al. Re: "effectiveness of adjuvanted influenza vaccination in elderly subjects in northern Italy". 2013 Am. J. Epidemiol. pmid:23436898
Hosogaya N et al. The heme-binding protein Dap1 links iron homeostasis to azole resistance via the P450 protein Erg11 in Candida glabrata. 2013 FEMS Yeast Res. pmid:23496820
Rappuoli R Vaccine adjuvants: the future is bright. Interview by Jenaid Rees. 2013 Expert Rev Vaccines pmid:23829664
Trung Bui D et al. Polymer prodrug nanoparticles based on naturally occurring isoprenoid for anticancer therapy. 2013 Biomacromolecules pmid:23829862
Bruun Laursen A [Catastrophic consequences of Pandemrix swine flu vaccine containing squalene]. 2013 Ugeskr. Laeg. pmid:23833781
Mølbak K [Squalene unlikely sinner]. 2013 Ugeskr. Laeg. pmid:23833782
Gefenaite G et al. Effectiveness of A(H1N1)pdm09 influenza vaccine in adults recommended for annual influenza vaccination. 2013 PLoS ONE pmid:23840413
Son J et al. Immunogenicity of low-dose MF59-adjuvanted 2009 influenza A/H1N1 vaccine in dialysis patients. 2013 Clin. Exp. Nephrol. pmid:22990301
Durier C et al. Long-term immunogenicity of two doses of 2009 A/H1N1v vaccine with and without AS03(A) adjuvant in HIV-1-infected adults. 2013 AIDS pmid:23018437
Rigane G et al. Effect of storage on refined olive oil composition: stabilization by addition of chlorophyll pigments and squalene. 2013 J Oleo Sci pmid:24292349
Esche R et al. Online LC-GC-based analysis of minor lipids in various tree nuts and peanuts. 2013 J. Agric. Food Chem. pmid:24251555
Ueda D et al. Cyclization of squalene from both termini: identification of an onoceroid synthase and enzymatic synthesis of ambrein. 2013 J. Am. Chem. Soc. pmid:24274794