| MeSH term | MeSH ID | Detail |
|---|---|---|
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Arthritis, Experimental | D001169 | 24 associated lipids |
| Lymphoma, B-Cell | D016393 | 24 associated lipids |
| Cholestasis | D002779 | 23 associated lipids |
| Periodontitis | D010518 | 22 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Cholelithiasis | D002769 | 16 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Hyperlipoproteinemias | D006951 | 15 associated lipids |
| Demyelinating Diseases | D003711 | 15 associated lipids |
| Rosacea | D012393 | 13 associated lipids |
| Dermatitis, Occupational | D009783 | 12 associated lipids |
| Keloid | D007627 | 12 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Influenza, Human | D007251 | 11 associated lipids |
| Hepatitis | D006505 | 11 associated lipids |
| Pregnancy Complications, Infectious | D011251 | 11 associated lipids |
| Scalp Dermatoses | D012536 | 11 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Koval'ova VA et al. | [Effects of natural antioxidants on the content of lipids, proteins and carbohydrates in rat's gastric mucosal cells under experimental ulceration]. | 2014 | Fiziol Zh | pmid:25007524 |
| Liu CI et al. | Structural insights into the catalytic mechanism of human squalene synthase. | 2014 | Acta Crystallogr. D Biol. Crystallogr. | pmid:24531458 |
| Wołosik K et al. | The importance and perspective of plant-based squalene in cosmetology. | 2013 Jan-Feb | J Cosmet Sci | pmid:23449131 |
| Goff PH et al. | Adjuvants and immunization strategies to induce influenza virus hemagglutinin stalk antibodies. | 2013 | PLoS ONE | pmid:24223176 |
| Yüzbaşıoğlu D et al. | Genotoxicity assessment of vaccine adjuvant squalene. | 2013 | Food Chem. Toxicol. | pmid:23454296 |
| Malmierca MG et al. | Relevance of trichothecenes in fungal physiology: disruption of tri5 in Trichoderma arundinaceum. | 2013 | Fungal Genet. Biol. | pmid:23454546 |
| RodrÃguez-López J et al. | Epoxide-opening cascades triggered by a Nicholas reaction: total synthesis of teurilene. | 2013 | Angew. Chem. Int. Ed. Engl. | pmid:23436322 |
| Kabuto H et al. | Effects of squalene/squalane on dopamine levels, antioxidant enzyme activity, and fatty acid composition in the striatum of Parkinson's disease mouse model. | 2013 | J Oleo Sci | pmid:23357814 |
| Vinay TN et al. | Inactivated vaccine against viral hemorrhagic septicemia (VHS) emulsified with squalene and aluminum hydroxide adjuvant provides long term protection in olive flounder (Paralichthys olivaceus). | 2013 | Vaccine | pmid:23896420 |
| Ito R et al. | Effect of cation-π interactions and steric bulk on the catalytic action of oxidosqualene cyclase: a case study of Phe728 of β-amyrin synthase from Euphorbia tirucalli L. | 2013 | Chemistry | pmid:24203491 |