(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zambonin CG et al. | Laser desorption/ionization time-of-flight mass spectrometry of squalene in oil samples. | 2006 | Rapid Commun. Mass Spectrom. | pmid:16345138 |
| de Roux A et al. | Impact of corticosteroids on the immune response to a MF59-adjuvanted influenza vaccine in elderly COPD-patients. | 2006 | Vaccine | pmid:16288937 |
| Singh M et al. | A preliminary evaluation of alternative adjuvants to alum using a range of established and new generation vaccine antigens. | 2006 | Vaccine | pmid:16300864 |
| Gonor KV et al. | [The influence of diet with including amaranth oil on lipid metabolism in patients with ischemic heart disease and hyperlipoproteidemia]. | 2006 | Vopr Pitan | pmid:16862949 |
| Kulakova SN et al. | [Amaranths oil: peculiarities of chemical composition and influence on lipid metabolism by rats]. | 2006 | Vopr Pitan | pmid:16862953 |
| Järvisalo M et al. | Cholesterol absorption and synthesis in children with type 1 diabetes. | 2006 | Diabetes Care | pmid:17003310 |
| Del Giudice G et al. | Vaccines with the MF59 adjuvant do not stimulate antibody responses against squalene. | 2006 | Clin. Vaccine Immunol. | pmid:16960112 |
| Barrero AF et al. | Solid-phase selenium-catalyzed selective allylic chlorination of polyprenoids: facile syntheses of biologically active terpenoids. | 2006 | J. Org. Chem. | pmid:16839173 |
| Global Advisory Committee on Vaccine Safety, 6-7 June 2006. | 2006 | Wkly. Epidemiol. Rec. | pmid:16841398 | |
| Vajdy M et al. | Hepatitis C virus polyprotein vaccine formulations capable of inducing broad antibody and cellular immune responses. | 2006 | J. Gen. Virol. | pmid:16847121 |
| Nissinen MJ et al. | Effects of plant stanol esters supplied in a fat free milieu by pastilles on cholesterol metabolism in colectomized human subjects. | 2006 | Nutr Metab Cardiovasc Dis | pmid:16935701 |
| Kalinova J et al. | Distribution of Vitamin E, squalene, epicatechin, and rutin in common buckwheat plants (Fagopyrum esculentum Moench). | 2006 | J. Agric. Food Chem. | pmid:16848513 |
| Piotrowski PC et al. | Statins inhibit growth of human endometrial stromal cells independently of cholesterol availability. | 2006 | Biol. Reprod. | pmid:16571871 |
| Del Giudice G et al. | An MF59-adjuvanted inactivated influenza vaccine containing A/Panama/1999 (H3N2) induced broader serological protection against heterovariant influenza virus strain A/Fujian/2002 than a subunit and a split influenza vaccine. | 2006 | Vaccine | pmid:16464520 |
| Siirtola A et al. | Cholesterol absorption and synthesis in pediatric kidney, liver, and heart transplant recipients. | 2006 | Transplantation | pmid:16477216 |
| Singh DK and Porter TD | Inhibition of sterol 4alpha-methyl oxidase is the principal mechanism by which garlic decreases cholesterol synthesis. | 2006 | J. Nutr. | pmid:16484558 |
| Lodeiro S et al. | A putative precursor of isomalabaricane triterpenoids from lanosterol synthase mutants. | 2006 | Org. Lett. | pmid:16435854 |
| Matsuda SP et al. | Mechanistic insights into triterpene synthesis from quantum mechanical calculations. Detection of systematic errors in B3LYP cyclization energies. | 2006 | Org. Biomol. Chem. | pmid:16446812 |
| Szostak WB and Szostak-Wegierek D | [Health properties of shark oil]. | 2006 | Prz. Lek. | pmid:17083160 |
| Morikubo N et al. | Cation-pi interaction in the polyolefin cyclization cascade uncovered by incorporating unnatural amino acids into the catalytic sites of squalene cyclase. | 2006 | J. Am. Chem. Soc. | pmid:17017798 |
| Winne JM et al. | Application of the B-alkyl suzuki-miyaura cross-coupling reaction to the stereoselective synthesis of analogues of (3S)-oxidosqualene. | 2006 | Org. Lett. | pmid:17020310 |
| Morimoto Y et al. | Two-directional synthesis and stereochemical assignment toward a C2 symmetric oxasqualenoid (+)-intricatetraol. | 2006 | Org. Biomol. Chem. | pmid:17036107 |
| Atmar RL et al. | Safety and immunogenicity of nonadjuvanted and MF59-adjuvanted influenza A/H9N2 vaccine preparations. | 2006 | Clin. Infect. Dis. | pmid:17029131 |
| Nichol KL and Treanor JJ | Vaccines for seasonal and pandemic influenza. | 2006 | J. Infect. Dis. | pmid:17163383 |
| Peltola P et al. | Visceral obesity is associated with high levels of serum squalene. | 2006 | Obesity (Silver Spring) | pmid:16899796 |
| Stephenson I et al. | Phase I evaluation of intranasal trivalent inactivated influenza vaccine with nontoxigenic Escherichia coli enterotoxin and novel biovector as mucosal adjuvants, using adult volunteers. | 2006 | J. Virol. | pmid:16641287 |
| Suzuki M et al. | Lanosterol synthase in dicotyledonous plants. | 2006 | Plant Cell Physiol. | pmid:16531458 |
| Senthilkumar S et al. | Attenuation of cyclophosphamide induced toxicity by squalene in experimental rats. | 2006 | Chem. Biol. Interact. | pmid:16554041 |
| Köhler SP et al. | Molecular dynamics study to identify the reactive sites of a liquid squalane surface. | 2006 | J Phys Chem B | pmid:16800468 |
| Schneiders MS et al. | Manipulation of isoprenoid biosynthesis as a possible therapeutic option in mevalonate kinase deficiency. | 2006 | Arthritis Rheum. | pmid:16802371 |
| Spanggord RJ et al. | Enhancement of an analytical method for the determination of squalene in anthrax vaccine adsorbed formulations. | 2006 | J Pharm Biomed Anal | pmid:16762524 |
| Ottaviani M et al. | Peroxidated squalene induces the production of inflammatory mediators in HaCaT keratinocytes: a possible role in acne vulgaris. | 2006 | J. Invest. Dermatol. | pmid:16778793 |
| Hallikainen M et al. | Postprandial behavior of plasma squalene and non-cholesterol sterols in men with varying cholesterol absorption. | 2006 | Clin. Chim. Acta | pmid:16814761 |
| Zadák Z et al. | Polyunsaturated fatty acids, phytosterols and cholesterol metabolism in the Mediterranean diet. | 2006 | Acta Medica (Hradec Kralove) | pmid:16696439 |
| Senthilkumar S et al. | Effect of squalene on cyclophosphamide-induced toxicity. | 2006 | Clin. Chim. Acta | pmid:16150433 |
| Farvin KH et al. | Cardioprotective effect of squalene on lipid profile in isoprenaline-induced myocardial infarction in rats. | 2006 | J Med Food | pmid:17201641 |
| Gonor KV et al. | [The influence of a diet with including amaranth oil on antioxidant and immune status in patients with ischemic heart disease and hyperlipoproteidemia]. | 2006 | Vopr Pitan | pmid:17313043 |
| Gabutti G et al. | Safety and immunogenicity of conventional subunit and MF59-adjuvanted influenza vaccines in human immunodeficiency virus-1-seropositive patients. | 2005 Jul-Aug | J. Int. Med. Res. | pmid:16104444 |
| Ekanayake-Mudiyanselage S et al. | Vitamin E delivery to human skin by a rinse-off product: penetration of alpha-tocopherol versus wash-out effects of skin surface lipids. | 2005 Jan-Feb | Skin Pharmacol Physiol | pmid:15608499 |
| Cincinelli A et al. | Enrichment of organic pollutants in the sea surface microlayer (SML) at Terra Nova Bay, Antarctica: influence of SML on superficial snow composition. | 2005 | J Environ Monit | pmid:16307088 |
| Shan H et al. | Enzymatic cyclization of dioxidosqualene to heterocyclic triterpenes. | 2005 | J. Am. Chem. Soc. | pmid:16366544 |
| Zhang Y et al. | [Chemical constituents from the mangrove plant Ceriops tagal]. | 2005 | Yao Xue Xue Bao | pmid:16408813 |
| Tanaka H et al. | Enzymatic formation of indole-containing unnatural cyclic polyprenoids by bacterial squalene:hopene cyclase. | 2005 | Org. Lett. | pmid:16354088 |
| Hung CF et al. | Physicochemical characterization and gene transfection efficiency of lipid emulsions with various co-emulsifiers. | 2005 | Int J Pharm | pmid:15652212 |
| Henryk T et al. | [The effect of alcoxyglycerols, squalene and n-3 fatty acid on some innate immunity parameters in healthy people]. | 2005 | Pol. Merkur. Lekarski | pmid:15997638 |
| Blagović B et al. | Lipid analysis of the plasma membrane and mitochondria of brewer's yeast. | 2005 | Folia Microbiol. (Praha) | pmid:15954530 |
| Giner JL et al. | Detection of 1,2-hydride shifts in the formation of euph-7-ene by the squalene-tetrahymanol cyclase of Tetrahymena pyriformis. | 2005 | Chem. Commun. (Camb.) | pmid:15959594 |
| Kim TW et al. | Airway gene transfer using cationic emulsion as a mucosal gene carrier. | 2005 | J Gene Med | pmid:15929068 |
| Lavoie JM and Stevanovic T | Variation of chemical composition of the lipophilic extracts from yellow birch (Betula alleghaniensis) foliage. | 2005 | J. Agric. Food Chem. | pmid:15941310 |
| Xiong Q et al. | Structure and reactivity of the dammarenyl cation: configurational transmission in triterpene synthesis. | 2005 | J. Org. Chem. | pmid:15989315 |