(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Crilly JF and Earnshaw JC | Photon correlation spectroscopy of bilayer lipid membranes. | 1983 | Biophys. J. | pmid:6838962 |
| Tilvis RS and Miettinen TA | Dietary squalene increases tissue sterols and fecal bile acids in the rat. | 1983 | Lipids | pmid:6835033 |
| Pasechnik VI | [Cooperative analysis of measurements of capacity and optical parameters of bilayer lipid membranes]. | 1983 Jan-Feb | Biofizika | pmid:6830905 |
| Schroepfer GJ | Sterol biosynthesis. | 1982 | Annu. Rev. Biochem. | pmid:6810750 |
| Kling D and Gamble W | Cholesterol biosynthesis in polychlorinated biphenyl-treated rats. | 1982 | Environ. Res. | pmid:6802634 |
| Yamanishi Y et al. | Serum squalene levels in hepatobiliary diseases. | 1978 | Clin. Chim. Acta | pmid:679482 |
| Rohmer M et al. | Non-specific lanosterol and hopanoid biosynthesis be a cell-free system from the bacterium Methylococcus capsulatus. | 1980 | Eur. J. Biochem. | pmid:6780348 |
| Bouvier P et al. | Non-specific biosynthesis of gammacerane derivatives by a cell-free system from the protozoon Tetrahymena pyriformis. Conformations of squalene, (3S)-squalene epoxide and (3R)-squalene epoxide during the cyclization. | 1980 | Eur. J. Biochem. | pmid:6780347 |
| Miettinen TA | Phytosterolaemia, xanthomatosis and premature atherosclerotic arterial disease: a case with high plant sterol absorption, impaired sterol elimination and low cholesterol synthesis. | 1980 | Eur. J. Clin. Invest. | pmid:6768564 |
| Hata S et al. | Effect of detergents on sterol synthesis in a cell-free system of yeast. | 1982 | J. Lipid Res. | pmid:6752317 |
| Buttke TM and Pyle AL | Effects of unsaturated fatty acid deprivation on neutral lipid synthesis in Saccharomyces cerevisiae. | 1982 | J. Bacteriol. | pmid:6752117 |
| Salvioli G et al. | Relationships between squalene and cholesterol in bile: effect of ursodeoxycholic acid administration in patients with radiolucent gallstones. | 1984 | Metab. Clin. Exp. | pmid:6738365 |
| Uotani J | [The changes of sterol in lenses]. | 1984 | Nippon Ganka Gakkai Zasshi | pmid:6711397 |
| Wysocki SJ et al. | Simultaneous assessment of fetal lung maturity and sebaceous gland function by gas chromatography. | 1984 | Clin. Chim. Acta | pmid:6705230 |
| Gavey KL and Scallen TJ | Studies on the conversion of enzymatically generated, microsome-bound squalene to sterol. | 1978 | J. Biol. Chem. | pmid:670211 |
| Amdur BH et al. | Presence of squalene in gram-positive bacteria. | 1978 | J. Bacteriol. | pmid:670148 |
| Yachnin S and Mannickarottu V | Increased 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesterol biosynthesis in freshly isolated hairy cell leukemia cells. | 1984 | Blood | pmid:6696995 |
| Dykes PJ et al. | Analysis of the non-ionic detergent-soluble lipids of human stratum corneum. | 1984 | Br. J. Dermatol. | pmid:6696844 |
| Zaaijer D and van der Horst CJ | Cyclic changes in hormones, carbohydrates and indole metabolism in cervical mucus of normal, fertilizing cows and the relationship with non-fertility. | 1983 | Cytobios | pmid:6684538 |
| Aguilera JA et al. | Incorporation of mevalonate into squalene, lanosterol and cholesterol by different neonatal chick tissues. | 1983 | Int. J. Biochem. | pmid:6653866 |
| Rahier A et al. | Inhibition of 2,3-oxidosqualene: beta-amyrin-cyclase, S-adenosyl-L-methionine: cycloartenol C-24-methyltransferase and cycloeucalenol: obtusifoliol isomerase by rationally designed molecules containing a tertiary amine function. | 1983 | Biochem. Soc. Trans. | pmid:6642064 |
| Bell FP and Hubert EV | Evidence that chlorpromazine inhibits sterologenesis at post-HMGCoA reductase sites in rat liver, in vitro. | 1983 | Lipids | pmid:6633175 |
| Strandberg TE | Sterol synthesis from biliary squalene in the jejunal mucosa of the rat in vivo. | 1983 | Lipids | pmid:6621260 |
| Kajiyama G et al. | Serum squalene in patients with gallstones. | 1983 | Hiroshima J. Med. Sci. | pmid:6618897 |
| Linares A et al. | Squalene, lanosterol and cholesterol synthesis from acetate in neonatal chick tissues. | 1984 | Rev. Esp. Fisiol. | pmid:6531508 |
| Peyronel D et al. | Fatty acid and squalene compositions of Mediterranean Centrophorus SPP egg and liver oils in relation to age. | 1984 | Lipids | pmid:6503627 |
| Schroeder F et al. | Correlation of tumor metastasis with sterol carrier protein and plasma membrane sterol levels. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6497882 |
| Ohsawa K et al. | The possible role of squalene and its peroxide of the sebum in the occurrence of sunburn and protection from the damage caused by U.V. irradiation. | 1984 | J Toxicol Sci | pmid:6481825 |
| Chin J and Bloch K | Role of supernatant protein factor and anionic phospholipid in squalene uptake and conversion by microsomes. | 1984 | J. Biol. Chem. | pmid:6480582 |
| Arce V et al. | The in vivo incorporation of acetate into different non-saponifiable lipids by neonatal chick tissues. | 1984 | Comp. Biochem. Physiol., B | pmid:6478791 |
| Miettinen TA | Cholesterol and bile acid synthesis in two families with homozygous and heterozygous hypercholesterolemia. | 1984 Jul-Aug | Arteriosclerosis | pmid:6466195 |
| Bhavnani BR | Oestrogen biosynthesis in the pregnant mare. | 1981 | J. Endocrinol. | pmid:6453917 |
| Strauss JS et al. | The effect of marked inhibition of sebum production with 13cis-retinoic acid on skin surface lipid composition. | 1980 | J. Invest. Dermatol. | pmid:6444323 |
| Chen HW and Leonard DA | Chloroquine inhibits cyclization of squalene oxide to lanosterol in mammalian cells. | 1984 | J. Biol. Chem. | pmid:6429139 |
| Scott MT et al. | Adjuvant requirements for protective immunization of mice using a Trypanosoma cruzi 90K cell surface glycoprotein. | 1984 | Int. Arch. Allergy Appl. Immunol. | pmid:6429057 |
| Richter E et al. | Stimulation of the faecal excretion of 2,4,5,2',4',5'-hexachlorobiphenyl in rats by squalane. | 1983 | Xenobiotica | pmid:6415933 |
| Takeuchi N et al. | Impairment of hepatic cholesterol synthesis from squalene and the function of hepatic sterol carrier protein system by ageing. | 1978 | Exp. Gerontol. | pmid:639893 |
| Wielgosz GJ and Armstrong DT | Effects of prolactin, progesterone, and 17beta-hydroxy-5alpha-androstan-3-one on squalene production by the preputial gland of the immature female rat. | 1978 | Can. J. Physiol. Pharmacol. | pmid:638868 |
| Wood SG and Gottlieb D | Evidence from cell-free systems for differences in the sterol biosynthetic pathway of Rhizoctonia solani and Phytophthora cinnamomi. | 1978 | Biochem. J. | pmid:637850 |
| Wood SG and Gottlieb D | Evidence from mycelial studies for differences in the sterol biosynthetic pathway of Rhizoctonia solani and Phytophthora cinnamomi. | 1978 | Biochem. J. | pmid:637849 |
| Ryder NS et al. | Effect of the antimycotic drug naftifine on growth of and sterol biosynthesis in Candida albicans. | 1984 | Antimicrob. Agents Chemother. | pmid:6375557 |
| Jahnke L and Klein HP | Oxygen requirements for formation and activity of the squalene epoxidase in Saccharomyces cerevisiae. | 1983 | J. Bacteriol. | pmid:6348021 |
| Pinto WJ et al. | Stereochemically distinct roles for sterol in Saccharomyces cerevisiae. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6340686 |
| Pinto WJ and Nes WR | Stereochemical specificity for sterols in Saccharomyces cerevisiae. | 1983 | J. Biol. Chem. | pmid:6339498 |
| Tilvis RS et al. | Release of newly synthesized squalene, methyl sterols and cholesterol from human adipocytes in the presence of lipoproteins. | 1978 | Scand. J. Clin. Lab. Invest. | pmid:628820 |
| Bachman D et al. | Effect of bacille Calmette-Guerin immunotherapy on feline sarcoma virus-induced neoplasms in the cat. | 1982 | Am. J. Vet. Res. | pmid:6280529 |
| Stewart ME et al. | Suppression of sebum secretion with 13-cis-retinoic acid: effect on individual skin surface lipids and implications for their anatomic origin. | 1984 | J. Invest. Dermatol. | pmid:6228612 |
| Matsuo I et al. | Mechanism of skin surface lipid peroxidation. | 1983 | Curr. Probl. Dermatol. | pmid:6197240 |
| Richter E et al. | Excretion of beta-hexachlorocyclohexane by the rat as influenced by oral paraffin, squalane, and Lutrol E 400. | 1981 | Ecotoxicol. Environ. Saf. | pmid:6170505 |
| Lay JP et al. | Metabolism of beta-hexachlorocyclohexane-14C in rats following low dosing in the daily diet. | 1981 | J Environ Sci Health B | pmid:6166652 |