(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Huang ZR et al. | Biological and pharmacological activities of squalene and related compounds: potential uses in cosmetic dermatology. | 2009 | Molecules | pmid:19169201 |
Banzhoff A et al. | MF59-adjuvanted H5N1 vaccine induces immunologic memory and heterotypic antibody responses in non-elderly and elderly adults. | 2009 | PLoS ONE | pmid:19197383 |
Tritto E et al. | Mechanism of action of licensed vaccine adjuvants. | 2009 | Vaccine | pmid:19200813 |
Ansaldi F et al. | Adjuvanted seasonal influenza vaccines and perpetual viral metamorphosis: the importance of cross-protection. | 2009 | Vaccine | pmid:19200846 |
Galli G et al. | Adjuvanted H5N1 vaccine induces early CD4+ T cell response that predicts long-term persistence of protective antibody levels. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19237568 |
Lambrecht BN et al. | Mechanism of action of clinically approved adjuvants. | 2009 | Curr. Opin. Immunol. | pmid:19246182 |
Morimoto Y et al. | Total synthesis and determination of the absolute configuration of (+)-omaezakianol. | 2009 | Angew. Chem. Int. Ed. Engl. | pmid:19248063 |
Burke B et al. | Neutralizing antibody responses to subtype B and C adjuvanted HIV envelope protein vaccination in rabbits. | 2009 | Virology | pmid:19249806 |
Baudner BC et al. | MF59 emulsion is an effective delivery system for a synthetic TLR4 agonist (E6020). | 2009 | Pharm. Res. | pmid:19255727 |
Radak BK et al. | Modeling reactive scattering of F(2P) at a liquid squalane interface: a hybrid QM/MM molecular dynamics study. | 2009 | J Phys Chem A | pmid:19323516 |
Liu Y et al. | Influence of squalene feeding on plasma leptin, testosterone & blood pressure in rats. | 2009 | Indian J. Med. Res. | pmid:19293441 |
Pass RF et al. | Vaccine prevention of maternal cytomegalovirus infection. | 2009 | N. Engl. J. Med. | pmid:19297572 |
Kato S et al. | Biological safety of LipoFullerene composed of squalane and fullerene-C60 upon mutagenesis, photocytotoxicity, and permeability into the human skin tissue. | 2009 | Basic Clin. Pharmacol. Toxicol. | pmid:19371265 |
Campagnac E et al. | Fenpropimorph slows down the sterol pathway and the development of the arbuscular mycorrhizal fungus Glomus intraradices. | 2009 | Mycorrhiza | pmid:19340463 |
Cheng J and Hoshino T | Cyclization cascade of the C33-bisnorheptaprenoid catalyzed by recombinant squalene cyclase. | 2009 | Org. Biomol. Chem. | pmid:19343258 |
Ryu A et al. | Squalene as a target molecule in skin hyperpigmentation caused by singlet oxygen. | 2009 | Biol. Pharm. Bull. | pmid:19721223 |
Clark TW et al. | Trial of 2009 influenza A (H1N1) monovalent MF59-adjuvanted vaccine. | 2009 | N. Engl. J. Med. | pmid:19745215 |
Ghimire GP et al. | Improved squalene production via modulation of the methylerythritol 4-phosphate pathway and heterologous expression of genes from Streptomyces peucetius ATCC 27952 in Escherichia coli. | 2009 | Appl. Environ. Microbiol. | pmid:19767465 |
Shabtay A et al. | The potential of Pleurotus-treated olive mill solid waste as cattle feed. | 2009 | Bioresour. Technol. | pmid:19683915 |
Pedroso N et al. | Modulation of plasma membrane lipid profile and microdomains by H2O2 in Saccharomyces cerevisiae. | 2009 | Free Radic. Biol. Med. | pmid:19027845 |
Laitinen K et al. | Plant stanol ester spreads as components of a balanced diet for pregnant and breast-feeding women: evaluation of clinical safety. | 2009 | Br. J. Nutr. | pmid:19017423 |
Godio RP and MartÃn JF | Modified oxidosqualene cyclases in the formation of bioactive secondary metabolites: biosynthesis of the antitumor clavaric acid. | 2009 | Fungal Genet. Biol. | pmid:19130892 |
Wertz PW | Human synthetic sebum formulation and stability under conditions of use and storage. | 2009 | Int J Cosmet Sci | pmid:19134124 |
Matyas GR et al. | Lipid binding properties of 4E10, 2F5, and WR304 monoclonal antibodies that neutralize HIV-1. | 2009 | Biochim. Biophys. Acta | pmid:19100711 |
Ghimire GP et al. | Squalene-hopene cyclase (Spterp25) from Streptomyces peucetius: sequence analysis, expression and functional characterization. | 2009 | Biotechnol. Lett. | pmid:19116691 |
Alam MM et al. | Phase behavior, formation, and rheology of cubic phase and related gel emulsion in Tween 80/water/oil systems. | 2009 | J Oleo Sci | pmid:19491531 |
Herchi W et al. | Characterization and quantification of the aliphatic hydrocarbon fraction during linseed development ( Linum usitatissimum L.). | 2009 | J. Agric. Food Chem. | pmid:19492811 |
Cho S et al. | High-dose squalene ingestion increases type I procollagen and decreases ultraviolet-induced DNA damage in human skin in vivo but is associated with transient adverse effects. | 2009 | Clin. Exp. Dermatol. | pmid:19522983 |
Petrick L and Dubowski Y | Heterogeneous oxidation of squalene film by ozone under various indoor conditions. | 2009 | Indoor Air | pmid:19500173 |
Rodas B and Bressani R | [The oil, fatty acid and squalene content of varieties of raw and processed amaranth grain]. | 2009 | Arch Latinoam Nutr | pmid:19480349 |
Mantzouridou F et al. | Squalene versus ergosterol formation using Saccharomyces cerevisiae: combined effect of oxygen supply, inoculum size, and fermentation time on yield and selectivity of the bioprocess. | 2009 | J. Agric. Food Chem. | pmid:19537785 |
Vesikari T et al. | Enhanced immunogenicity of seasonal influenza vaccines in young children using MF59 adjuvant. | 2009 | Pediatr. Infect. Dis. J. | pmid:19561422 |
Bullon P et al. | Gingival vascular damage in atherosclerotic rabbits: hydroxytyrosol and squalene benefits. | 2009 | Food Chem. Toxicol. | pmid:19545596 |
Tokuhiro K et al. | Overproduction of geranylgeraniol by metabolically engineered Saccharomyces cerevisiae. | 2009 | Appl. Environ. Microbiol. | pmid:19592534 |
López P and MartÃn J | Potential chemosignals associated with male identity in the amphisbaenian Blanus cinereus. | 2009 | Chem. Senses | pmid:19406874 |
Al-Edresi S and Baie S | Formulation and stability of whitening VCO-in-water nano-cream. | 2009 | Int J Pharm | pmid:19429303 |
Camilloni B et al. | Cross-reactive antibodies in middle-aged and elderly volunteers after MF59-adjuvanted subunit trivalent influenza vaccine against B viruses of the B/Victoria or B/Yamagata lineages. | 2009 | Vaccine | pmid:19410623 |
Galli G et al. | Fast rise of broadly cross-reactive antibodies after boosting long-lived human memory B cells primed by an MF59 adjuvanted prepandemic vaccine. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19416838 |
Phillips CJ et al. | Antibodies to squalene in US Navy Persian Gulf War veterans with chronic multisymptom illness. | 2009 | Vaccine | pmid:19379786 |
Del Giudice G et al. | Seasonal influenza vaccine provides priming for A/H1N1 immunization. | 2009 | Sci Transl Med | pmid:20371459 |
Couvreur P | ["Squalenoylation": a new approach to the design of anticancer and antiviral nanomedicines]. | 2009 | Bull. Acad. Natl. Med. | pmid:19883017 |
Tong R et al. | Stereo- and regioselective synthesis of squalene tetraepoxide. | 2009 | J. Org. Chem. | pmid:19827774 |
Vesikari T et al. | MF59-adjuvanted influenza vaccine (FLUAD) in children: safety and immunogenicity following a second year seasonal vaccination. | 2009 | Vaccine | pmid:19840662 |
Kim ES et al. | Squalene-induced exogenous lipoid pneumonia in an infant. | 2009 | Pediatr Int | pmid:19799746 |
Torrecilla Rojas MA et al. | [Conventional influenza vaccination compared to MF59 adjuvanted subunit vaccine]. | 2009 | Aten Primaria | pmid:19800151 |
Laursen AB | [Dangerous adjuvant in swine influenza vaccine]. | 2009 | Ugeskr. Laeg. | pmid:19866499 |
Reddy LH and Couvreur P | Squalene: A natural triterpene for use in disease management and therapy. | 2009 | Adv. Drug Deliv. Rev. | pmid:19804806 |
Gerpe A et al. | 5-Nitrofuranes and 5-nitrothiophenes with anti-Trypanosoma cruzi activity and ability to accumulate squalene. | 2009 | Bioorg. Med. Chem. | pmid:19811923 |
Bildstein L et al. | Freeze-drying of squalenoylated nucleoside analogue nanoparticles. | 2009 | Int J Pharm | pmid:19782881 |
Leszczynska A et al. | Investigating the effects of statins on cellular lipid metabolism using a yeast expression system. | 2009 | PLoS ONE | pmid:20041128 |