(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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ROTHBLAT GH et al. | A quantitative colorimetric assay for squalene. | 1962 | Anal. Biochem. | pmid:14494417 |
HORLICK L and AVIGAN J | STEROLS OF SKIN IN THE NORMAL AND TRIPARANOL-TREATED RAT. | 1963 | J. Lipid Res. | pmid:14168146 |
LUPIEN PJ et al. | EFFECT OF AN ANTIBIOTIC ON LIPID FRACTIONS IN PLASMS AND EGG YOLK OF LAYING HENS. | 1963 | Can J Biochem Physiol | pmid:14083981 |
GRIESEMER RD and THOMAS RW | LIPOGENESIS IN HUMAN SKIN. II. THE EFFECT OF PHYSICAL AND CHEMICAL FACTORS ON IN VITRO LIPOGENESIS FROM ACETATE. | 1963 | J. Invest. Dermatol. | pmid:14059599 |
LIBERTI A et al. | ISOTOPIC EFFECTS IN GAS-LIQUID CHROMATOGRAPHY. I. GAS CHROMATOGRAPHIC BEHAVIOUR OF BENZENE AND PERDEUTEROBENZENE. | 1963 | J. Chromatogr. | pmid:14066512 |
GRIESEMER RD and THOMAS RW | LIPOGENESIS IN HUMAN SKIN. III. VARIATION WITH BODY SITE. | 1963 | J. Invest. Dermatol. | pmid:14066602 |
PROSTENIK M and MUNK-WEINERT M | The isolation of squalene from human brain. | 1963 | Biochim. Biophys. Acta | pmid:13986372 |
BURGESS TL and WILSON JD | Studies on hormonal regulation of squalene synthesis in preputial gland and skin of the rat. | 1963 | Proc. Soc. Exp. Biol. Med. | pmid:14016990 |
CALTABIANO S and SPREMOLLA G | [Histological and humoral aspects of experimental atherosclerosis induced by squalene in rabbits treated with triparanol]. | 1963 | Arch Sci Med (Torino) | pmid:14017944 |
CARAVACA J et al. | Inhibition of squalene and cholesterol biosynthesis by hepatocatalase (Caperase). | 1963 | Biochem. Biophys. Res. Commun. | pmid:14018515 |
CORNFORTH JW et al. | Stereospecific insertion of hydrogen atom into squalene from reduced nicotinamide-adenine dinucleotides. | 1963 | Biochem. Biophys. Res. Commun. | pmid:14023096 |
GAYLOR JL | Biosynthesis of skin sterols. III. Conversion of squalene to sterols by rat skin. | 1963 | J. Biol. Chem. | pmid:13946923 |
GAYLOR JL | Biosynthesis of skin sterols. V. Effect of arsenite inhibition and the accumulation of labeled lanosta-7, 24-dien-3 beta-ol in rat skin. | 1963 | Arch. Biochem. Biophys. | pmid:13946925 |
JACHYMCZYK W | [Biosynthesis of triterpenoid compounds]. | 1963 | Postepy Biochem. | pmid:13957182 |
BEELER DA et al. | The biosynthesis of squalene from mevalonic acid-2-C-14 and farnesyl pyrophosphate-4,8,12-C-14 by carrot and tomato enzymes. | 1963 | Arch. Biochem. Biophys. | pmid:13970235 |
SAMUELSSON B and GOODMAN DS | Stereochemistry of the hydrogen transfer to squalene during its biosynthesis from farnesyl pyrophosphate. | 1963 | Biochem. Biophys. Res. Commun. | pmid:13976173 |
DILLER ER and HARVEY OA | INTERRELATIONSHIP OF STEROL AND FATTY ACID BIOSYNTHESIS IN RAT LIVER SLICES AS RELATED TO DIETARY LIPID. | 1964 | Biochemistry | pmid:14269326 |
SAMUELSSON B and GOODMAN DS | STEREOCHEMISTRY AT THE CENTER OF SQUALENE DURING ITS BIOSYNTHESIS FROM FARNESYL PYROPHOSPHATE AND SUBSEQUENT CONVERSION TO CHOLESTEROL. | 1964 | J. Biol. Chem. | pmid:14114881 |
ALEXANDER GJ and ALEXANDER RB | INHIBITION OF CHOLESTEROL SYNTHESIS IN VIVO BY A CONVULSANT, METRAZOL. | 1964 | Proc. Soc. Exp. Biol. Med. | pmid:14117448 |
Krishna G et al. | An enzyme-bound intermediate in the conversion of farnesyl pyrophosphate to squalene. | 1964 | Biochem. Biophys. Res. Commun. | pmid:4284347 |