(e,e,e,e)-squalene

(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (e,e,e,e)-squalene?

(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene

MeSH term MeSH ID Detail
Keloid D007627 12 associated lipids
Rosacea D012393 13 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Demyelinating Diseases D003711 15 associated lipids
Cholelithiasis D002769 16 associated lipids
Celiac Disease D002446 16 associated lipids
Xanthomatosis D014973 17 associated lipids
Olfaction Disorders D000857 17 associated lipids
Periodontitis D010518 22 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with (e,e,e,e)-squalene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (e,e,e,e)-squalene?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (e,e,e,e)-squalene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (e,e,e,e)-squalene

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Authors Title Published Journal PubMed Link
Rao KS and Olson RE The effect of exogenous cholesterol on the synthesis in vivo of cholesterol, ubiquinone, and squalene in rat liver. 1967 Biochem. Biophys. Res. Commun. pmid:6030977
Arffmann E and Glavind J Studies by the newt test on carcinogenic properties of rats. 1967 Acta Pathol Microbiol Scand pmid:6050372
Benveniste P et al. [Biosynthesis of squalene with the help of microsomes originating from the tissue of tobacco cultivated in vitro]. 1967 C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat. pmid:4967365
Kishi M et al. Acid-catalyzed cyclization of squalene oxide. 1967 Chem. Pharm. Bull. pmid:5583148
Voogt PA Biosynthesis of 3-beta-sterols in a snail, Arion rufus L., from 1-14C-acetate. 1967 Arch. Int. Physiol. Biochim. pmid:4167714
Kellum RE Human sebaceous gland lipids. Analysis by thin-layer chromatography. 1967 Arch Dermatol pmid:6019001
Matschiner JT et al. Effect of indigestible oils on vitamin K deficiency in the rat. 1967 J. Nutr. pmid:6021812
Matschiner JT et al. Mechanism of the effect of retinoic acid and squalene on vitamin K deficiency in the rat. 1967 J. Nutr. pmid:6021953
Kellum RE Short chain fatty acids (below C12) of human skin surface lipids. 1967 J. Invest. Dermatol. pmid:6022603
Dean PD et al. A soluble 2,3-oxidosqualene sterol cyclase. 1967 J. Biol. Chem. pmid:6027261