(e,e,e,e)-squalene

(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (e,e,e,e)-squalene?

(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene

MeSH term MeSH ID Detail
Keloid D007627 12 associated lipids
Rosacea D012393 13 associated lipids
Demyelinating Diseases D003711 15 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Cholelithiasis D002769 16 associated lipids
Celiac Disease D002446 16 associated lipids
Xanthomatosis D014973 17 associated lipids
Olfaction Disorders D000857 17 associated lipids
Periodontitis D010518 22 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with (e,e,e,e)-squalene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (e,e,e,e)-squalene?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (e,e,e,e)-squalene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (e,e,e,e)-squalene

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Authors Title Published Journal PubMed Link
SQUALENE and cholesterol synthesis in the human skin. 1956 Nutr. Rev. pmid:13309889
VILLALBA GOMEZ GM [Squalene index]. 1956 May-Aug Rev Sanid Asist Soc pmid:13379961
BOUGHTON B et al. Studies of sebum. VIII. Observations on the squalene and cholesterol content and the possible functions of squalene in human sebum. 1957 Biochem. J. pmid:13426103
HELLER JH et al. Squalene content of various shark livers. 1957 Nature pmid:13430738
TCHEN TT and BLOCH K On the conversion of squalene to lanosterol in vitro. 1957 J. Biol. Chem. pmid:13438881
TCHEN TT and BLOCH K On the mechanism of enzymatic cyclization of squalene. 1957 J. Biol. Chem. pmid:13438882
SOBEL H et al. Determinations of squalene in sebum from the forehead of patients with skin cancer. 1957 J. Invest. Dermatol. pmid:13491890
DITURI F et al. Precursors of squalene and cholesterol. 1957 J. Biol. Chem. pmid:13502345
CORNFORTH JW et al. Studies on the biosynthesis of cholesterol. 5. Biosynthesis of squalene from DL-3-hydroxy-3-methyl [2-14C] pentano-5-lactone. 1958 Biochem. J. pmid:13535596
WOLFF RE and GODEFROY N [Transformation of synthetic squalene (11, 1414C) to cholesterol in rats]. 1958 C. R. Hebd. Seances Acad. Sci. pmid:13537384