| MeSH term | MeSH ID | Detail |
|---|---|---|
| Keloid | D007627 | 12 associated lipids |
| Rosacea | D012393 | 13 associated lipids |
| Demyelinating Diseases | D003711 | 15 associated lipids |
| Hyperlipoproteinemias | D006951 | 15 associated lipids |
| Cholelithiasis | D002769 | 16 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Periodontitis | D010518 | 22 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gloor M et al. | Biochemical and physiological parameters on the healthy skin surface of patients with common warts. | 1976 | Dermatologica | pmid:939341 |
| Toews AD et al. | Tellurium causes dose-dependent coordinate down-regulation of myelin gene expression. | 1997 | Brain Res. Mol. Brain Res. | pmid:9387870 |
| Salamon Z et al. | Coupled plasmon-waveguide resonators: a new spectroscopic tool for probing proteolipid film structure and properties. | 1997 | Biophys. J. | pmid:9370473 |
| Tomasi M et al. | Strong mucosal adjuvanticity of cholera toxin within lipid particles of a new multiple emulsion delivery system for oral immunization. | 1997 | Eur. J. Immunol. | pmid:9368632 |
| Cataldo DM and Van Nest G | The adjuvant MF59 increases the immunogenicity and protective efficacy of subunit influenza vaccine in mice. | 1997 | Vaccine | pmid:9364672 |
| Kribii R et al. | Cloning and characterization of the Arabidopsis thaliana SQS1 gene encoding squalene synthase--involvement of the C-terminal region of the enzyme in the channeling of squalene through the sterol pathway. | 1997 | Eur. J. Biochem. | pmid:9363754 |
| Edmond J et al. | Mevalonate metabolism: role of kidneys. | 1976 | Science | pmid:935865 |
| Cornforth JW | Asymmetry and enzyme action. | 1976 | Science | pmid:935862 |
| Mansfield PD et al. | The effects of four, commercial ceruminolytic agents on the middle ear. | 1997 Nov-Dec | J Am Anim Hosp Assoc | pmid:9358414 |
| Grieveson LA et al. | A simplified squalene epoxidase assay based on an HPLC separation and time-dependent UV/visible determination of squalene. | 1997 | Anal. Biochem. | pmid:9324936 |
| Uusitupa MI et al. | Lathosterol and other non-cholesterol sterols during treatment of hypercholesterolaemia with beta-glucan-rich oat bran. | 1997 | Eur J Clin Nutr | pmid:9306087 |
| Wendt KU et al. | Structure and function of a squalene cyclase. | 1997 | Science | pmid:9295270 |
| Donald KA et al. | Effects of overproduction of the catalytic domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase on squalene synthesis in Saccharomyces cerevisiae. | 1997 | Appl. Environ. Microbiol. | pmid:9292983 |
| Hamdan JS and Casali AK | Effect of amphotericin B on the lipids of yeast cells of Sporothrix schenckii. | 1996-1997 | Mycopathologia | pmid:9276941 |
| Cenedella RJ | Posttranscriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in lens epithelial cells by mevalonate-derived nonsterols. | 1997 | Exp. Eye Res. | pmid:9237866 |
| Barnett SW et al. | Vaccination with HIV-1 gp120 DNA induces immune responses that are boosted by a recombinant gp120 protein subunit. | 1997 | Vaccine | pmid:9234536 |
| Flint OP et al. | Inhibition of cholesterol synthesis by squalene synthase inhibitors does not induce myotoxicity in vitro. | 1997 | Toxicol. Appl. Pharmacol. | pmid:9221828 |
| Fliesler SJ et al. | Squalene is localized to the plasma membrane in bovine retinal rod outer segments. | 1997 | Exp. Eye Res. | pmid:9176062 |
| Kuchta T et al. | Inhibition of ergosterol biosynthesis is not accompanied by a change in fatty acid composition in Saccharomyces cerevisiae treated with the antifungal agent 6-amino-2-n-pentylthiobenzothiazole. | 1997 | FEMS Microbiol. Lett. | pmid:9163904 |
| Morand OH et al. | Ro 48-8.071, a new 2,3-oxidosqualene:lanosterol cyclase inhibitor lowering plasma cholesterol in hamsters, squirrel monkeys, and minipigs: comparison to simvastatin. | 1997 | J. Lipid Res. | pmid:9162756 |