| MeSH term | MeSH ID | Detail |
|---|---|---|
| Keloid | D007627 | 12 associated lipids |
| Rosacea | D012393 | 13 associated lipids |
| Demyelinating Diseases | D003711 | 15 associated lipids |
| Hyperlipoproteinemias | D006951 | 15 associated lipids |
| Cholelithiasis | D002769 | 16 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Periodontitis | D010518 | 22 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Dracheva S et al. | Chemical and functional studies on the importance of purple membrane lipids in bacteriorhodopsin photocycle behavior. | 1996 | FEBS Lett. | pmid:8612754 |
| Astruc M et al. | Squalene epoxidase and oxidosqualene lanosterol-cyclase activities in cholesterogenic and non-cholesterogenic tissues. | 1977 | Biochim. Biophys. Acta | pmid:857899 |
| Ott G et al. | Enhancement of humoral response against human influenza vaccine with the simple submicron oil/water emulsion adjuvant MF59. | 1995 | Vaccine | pmid:8578842 |
| Henk G and Heinz T | [Hydrocarbon content in the fat of meat pigs after feeding "Fermosin"]. | 1993 | Arch Tierernahr | pmid:8572916 |
| Chan C et al. | The squalestatins: decarboxy and 4-deoxy analogues as potent squalene synthase inhibitors. | 1996 | J. Med. Chem. | pmid:8568810 |
| Airaudi D et al. | Preliminary screening of some squalenoid derivatives for toxicity towards dermatophytes. | 1995 Jul-Aug | Mycoses | pmid:8559196 |
| McKean ML and Nes WR | Delayed conversion of squalene to sterols during development of Pinus pinea seeds. | 1977 | Lipids | pmid:853880 |
| Kohasi O et al. | Arthritogenicity of wax D from various mycobacteria related to oil vehicle composition and to the combination with poly I:C, cord factor and acetylated wax D. | 1977 | Int. Arch. Allergy Appl. Immunol. | pmid:852904 |
| Socaciu C et al. | In vitro yeast (Saccharomyces cerevisiae) presqualene and squalene synthesis related to substrate and cofactor availability. | 1995 | C. R. Acad. Sci. III, Sci. Vie | pmid:8521075 |
| Horie M et al. | An inhibitor of squalene epoxidase, NB-598, suppresses the secretion of cholesterol and triacylglycerol and simultaneously reduces apolipoprotein B in HepG2 cells. | 1993 | Biochim. Biophys. Acta | pmid:8504141 |
| Prashad M | Amidinium cation as a mimic of allylic carbocation: synthesis and squalene synthetase inhibitory activity of an amidinium analog of a carbocation intermediate. | 1993 | J. Med. Chem. | pmid:8496942 |
| Seo S et al. | Effect of sterol biosynthesis inhibitor, SSF-109, on cholesterol synthesis in isolated rat hepatocytes. | 1993 | Steroids | pmid:8484187 |
| Balliano G et al. | Differential inhibition of fungal oxidosqualene cyclase by 6E and 6Z isomers of 2,3-epoxy-10-aza-10,11-dihydrosqualene. | 1993 | FEBS Lett. | pmid:8462686 |
| Asnis DS et al. | Shark oil pneumonia. An overlooked entity. | 1993 | Chest | pmid:8449116 |
| Gloor M and Karenfeld A | Effect of ultraviolet light therapy, given over a period of several weeks, on the amount and composition of the skin surface lipids. | 1977 | Dermatologica | pmid:844642 |
| Crispino GA et al. | Selective perhydroxylation of squalene: taming the arithmetic demon. | 1993 | Science | pmid:8418495 |
| Kawakami T et al. | Squalane as a possible carrier of bone morphogenetic protein. | 1993 | Biomaterials | pmid:8399948 |
| Lohner K et al. | Squalene promotes the formation of non-bilayer structures in phospholipid model membranes. | 1993 | Biochim. Biophys. Acta | pmid:8399307 |
| Storm HM et al. | Radioprotection of mice by dietary squalene. | 1993 | Lipids | pmid:8355581 |
| Miettinen TA and Vanhanen H | Serum concentration and metabolism of cholesterol during rapeseed oil and squalene feeding. | 1994 | Am. J. Clin. Nutr. | pmid:8310985 |