| MeSH term | MeSH ID | Detail |
|---|---|---|
| Dermatitis, Occupational | D009783 | 12 associated lipids |
| Rosacea | D012393 | 13 associated lipids |
| Demyelinating Diseases | D003711 | 15 associated lipids |
| Hyperlipoproteinemias | D006951 | 15 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Cholelithiasis | D002769 | 16 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Periodontitis | D010518 | 22 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Boyce TG et al. | Safety and immunogenicity of adjuvanted and unadjuvanted subunit influenza vaccines administered intranasally to healthy adults. | 2000 | Vaccine | pmid:10930676 |
| Gaber BP and Goodsell DS | The art of molecular graphics. Escape from flatland. | 2000 | J. Mol. Graph. Model. | pmid:10935209 |
| Viola F et al. | Stereospecific syntheses of trans-vinyldioxidosqualene and 3-hydroxysulfide derivatives, as potent and time-dependent 2,3-oxidosqualene cyclase inhibitors. | 2000 | Bioorg. Med. Chem. | pmid:10968281 |
| Fernández-MartÃn R et al. | ent-Kaurene and squalene synthesis in Fusarium fujikuroi cell-free extracts. | 2000 | Phytochemistry | pmid:10975508 |
| Ikeda U et al. | Fluvastatin inhibits matrix metalloproteinase-1 expression in human vascular endothelial cells. | 2000 | Hypertension | pmid:10988259 |
| Shimizu I and Katsuki H | Effect of temperature on ergosterol biosynthesis in yeast. | 1975 | J. Biochem. | pmid:1099086 |
| Barton DH et al. | Investigations on the biosynthesis of steroids and terpenoids. Part XII. Biosynthesis of 3beta-hydroxy-triterpenoids and -steroids from (3S)-2,3-epoxy-2,3-dihydrosqualene. | 1975 | J. Chem. Soc. Perkin Trans. I | pmid:1099108 |
| Giacomoni PU et al. | Aging of human skin: review of a mechanistic model and first experimental data. | 2000 | IUBMB Life | pmid:10995026 |
| Relas H et al. | Dietary squalene increases cholesterol synthesis measured with serum non-cholesterol sterols after a single oral dose in humans. | 2000 | Atherosclerosis | pmid:10998465 |
| Moreau JP et al. | Biosynthesis of sterols by a yeast homogenate. Incorporation of mevalonic acid into cholesta-5,7,24-trien-3beta-ol and 5alpha-cholesta-7,24-dien-3beta-ol. | 1975 | Eur. J. Biochem. | pmid:1100393 |