| MeSH term | MeSH ID | Detail |
|---|---|---|
| Otitis Media | D010033 | 12 associated lipids |
| Rosacea | D012393 | 13 associated lipids |
| Hyperlipoproteinemias | D006951 | 15 associated lipids |
| Demyelinating Diseases | D003711 | 15 associated lipids |
| Cholelithiasis | D002769 | 16 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Periodontitis | D010518 | 22 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wiss O and Wiss V | On metabolic degradations of squalene, lanosterol and cholesterol in rat liver in vivo. Evidence for recycling of metabolites for the synthesis of isoprene compounds. | 1977 | Helv. Chim. Acta | pmid:914630 |
| Perzl M et al. | Squalene-hopene cyclase from Bradyrhizobium japonicum: cloning, expression, sequence analysis and comparison to other triterpenoid cyclases. | 1997 | Microbiology (Reading, Engl.) | pmid:9141686 |
| Kawakami T et al. | Evaluation of heterotopic bone formation induced by squalane and bone morphogenetic protein composite. | 1997 | Clin. Orthop. Relat. Res. | pmid:9137198 |
| Granoff DM et al. | MF59 adjuvant enhances antibody responses of infant baboons immunized with Haemophilus influenzae type b and Neisseria meningitidis group C oligosaccharide-CRM197 conjugate vaccine. | 1997 | Infect. Immun. | pmid:9125551 |
| Gylling H et al. | Delayed postprandial retinyl palmitate and squalene removal in a patient heterozygous for apolipoprotein A-IFIN mutation (Leu 159-->Arg) and low HDL cholesterol level without coronary artery disease. | 1996 | Atherosclerosis | pmid:9125314 |
| Rangel H et al. | Naturally azole-resistant Leishmania braziliensis promastigotes are rendered susceptible in the presence of terbinafine: comparative study with azole-susceptible Leishmania mexicana promastigotes. | 1996 | Antimicrob. Agents Chemother. | pmid:9124841 |
| Eisele B et al. | Effects of a novel 2,3-oxidosqualene cyclase inhibitor on cholesterol biosynthesis and lipid metabolism in vivo. | 1997 | J. Lipid Res. | pmid:9101437 |
| Kushiro T et al. | In vitro conversion of 2,3-oxidosqualene into dammarenediol by Panax ginseng microsomes. | 1997 | Biol. Pharm. Bull. | pmid:9084891 |
| O'Hagan DT et al. | Recent advances in vaccine adjuvants: the development of MF59 emulsion and polymeric microparticles. | 1997 | Mol Med Today | pmid:9060004 |
| Baum CL et al. | Sterol carrier protein-2 overexpression enhances sterol cycling and inhibits cholesterol ester synthesis and high density lipoprotein cholesterol secretion. | 1997 | J. Biol. Chem. | pmid:9045674 |