| MeSH term | MeSH ID | Detail |
|---|---|---|
| Otitis Media | D010033 | 12 associated lipids |
| Rosacea | D012393 | 13 associated lipids |
| Hyperlipoproteinemias | D006951 | 15 associated lipids |
| Demyelinating Diseases | D003711 | 15 associated lipids |
| Cholelithiasis | D002769 | 16 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Periodontitis | D010518 | 22 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
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|---|---|---|---|---|
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| Ikematsu H et al. | Evaluation of immune response following one dose of an AS03A-adjuvanted H1N1 2009 pandemic influenza vaccine in Japanese adults 65 years of age or older. | 2012 | Hum Vaccin Immunother | pmid:22854661 |
| Nakazawa A et al. | Optimization of culture conditions of the thraustochytrid Aurantiochytrium sp. strain 18W-13a for squalene production. | 2012 | Bioresour. Technol. | pmid:22023965 |
| Niehaus TD et al. | Functional identification of triterpene methyltransferases from Botryococcus braunii race B. | 2012 | J. Biol. Chem. | pmid:22241476 |
| Iorio AM et al. | Influenza viruses and cross-reactivity in healthy adults: humoral and cellular immunity induced by seasonal 2007/2008 influenza vaccination against vaccine antigens and 2009 A(H1N1) pandemic influenza virus. | 2012 | Vaccine | pmid:22245606 |
| Block SL et al. | Dose-range study of MF59-adjuvanted versus nonadjuvanted monovalent A/H1N1 pandemic influenza vaccine in six- to less than thirty-six-month-old children. | 2012 | Pediatr. Infect. Dis. J. | pmid:22481427 |
| Sémiramoth N et al. | Self-assembled squalenoylated penicillin bioconjugates: an original approach for the treatment of intracellular infections. | 2012 | ACS Nano | pmid:22482704 |
| Langley JM et al. | Safety and immunogenicity of 2010-2011 H1N12009-containing trivalent inactivated influenza vaccine in children 12-59 months of age previously given AS03-adjuvanted H1N12009 pandemic vaccine: a PHAC/CIHR Influenza Research Network (PCIRN) study. | 2012 | Vaccine | pmid:22469860 |
| Fukase H et al. | Assessment of the immunogenicity and safety of varying doses of an MF59®-adjuvanted cell culture-derived A/H1N1 pandemic influenza vaccine in Japanese paediatric, adult and elderly subjects. | 2012 | Vaccine | pmid:22472791 |
| Suthiwong J et al. | A new phenolic compound from the stem of Hymenocardia wallichii. | 2012 | J Asian Nat Prod Res | pmid:22423644 |
| Zhang XH et al. | Chemical composition of volatile oils from the pericarps of Indian sandalwood (Santalum album) by different extraction methods. | 2012 | Nat Prod Commun | pmid:22428257 |
| Guzmán Herrador BR et al. | Usefulness of health registries when estimating vaccine effectiveness during the influenza A(H1N1)pdm09 pandemic in Norway. | 2012 | BMC Infect. Dis. | pmid:22429643 |
| Hatz C et al. | A randomized clinical trial to identify the optimal antigen and MF59(®) adjuvant dose of a monovalent A/H1N1 pandemic influenza vaccine in healthy adult and elderly subjects. | 2012 | Vaccine | pmid:22446638 |
| Lai RP et al. | Mixed adjuvant formulations reveal a new combination that elicit antibody response comparable to Freund's adjuvants. | 2012 | PLoS ONE | pmid:22509385 |
| Marinaro M et al. | A caprine herpesvirus 1 vaccine adjuvanted with MF59â„¢ protects against vaginal infection and interferes with the establishment of latency in goats. | 2012 | PLoS ONE | pmid:22511971 |
| Desmaële D et al. | Squalenoylation: a generic platform for nanoparticular drug delivery. | 2012 | J Control Release | pmid:21840355 |
| Naziri E et al. | Recovery of squalene from wine lees using ultrasound assisted extraction-a feasibility study. | 2012 | J. Agric. Food Chem. | pmid:22888984 |
| Czajka H et al. | A phase II, randomised clinical trial to demonstrate the non-inferiority of low-dose MF59-adjuvanted pre-pandemic A/H5N1 influenza vaccine in adult and elderly subjects. | 2012 | J Prev Med Hyg | pmid:23362618 |
| Takami T et al. | A genetic and pharmacological analysis of isoprenoid pathway by LC-MS/MS in fission yeast. | 2012 | PLoS ONE | pmid:23145048 |
| Langley JM et al. | A randomized, controlled non-inferiority trial comparing A(H1N1)pmd09 vaccine antigen, with and without AS03 adjuvant system, co-administered or sequentially administered with an inactivated trivalent seasonal influenza vaccine. | 2012 | BMC Infect. Dis. | pmid:23110320 |