| MeSH term | MeSH ID | Detail |
|---|---|---|
| Leukemia, Experimental | D007942 | 42 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Nervous System Diseases | D009422 | 37 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Thyroid Neoplasms | D013964 | 33 associated lipids |
| Micronuclei, Chromosome-Defective | D048629 | 33 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Vitamin E Deficiency | D014811 | 29 associated lipids |
| Brain Diseases | D001927 | 27 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kanaji N et al. | Positron emission tomography-positive squalene-induced lipoid pneumonia confirmed by gas chromatography-mass spectrometry of bronchoalveolar lavage fluid. | 2008 | Am. J. Med. Sci. | pmid:18414072 |
| Heikkinen T et al. | Safety of MF59-adjuvanted A/H1N1 influenza vaccine in pregnancy: a comparative cohort study. | 2012 | Am. J. Obstet. Gynecol. | pmid:22939717 |
| Carlson BC et al. | The endogenous adjuvant squalene can induce a chronic T-cell-mediated arthritis in rats. | 2000 | Am. J. Pathol. | pmid:10854227 |
| Falcone DJ et al. | Enhancement of cholesterol and cholesteryl ester accumulation in re-endothelialized aorta. | 1980 | Am. J. Pathol. | pmid:7361865 |
| Hoffman SL et al. | Safety, immunogenicity, and efficacy of a malaria sporozoite vaccine administered with monophosphoryl lipid A, cell wall skeleton of mycobacteria, and squalane as adjuvant. | 1994 | Am. J. Trop. Med. Hyg. | pmid:7985753 |
| Bachman D et al. | Effect of bacille Calmette-Guerin immunotherapy on feline sarcoma virus-induced neoplasms in the cat. | 1982 | Am. J. Vet. Res. | pmid:6280529 |
| Ruiz-Aragón J et al. | [Assessment of the MF59-adjuvanted pandemic influenza A/H1N1 vaccine. Systematic review of literature]. | 2013 | An Pediatr (Barc) | pmid:23490433 |
| ROTHBLAT GH et al. | A quantitative colorimetric assay for squalene. | 1962 | Anal. Biochem. | pmid:14494417 |
| Tait RM | Development of a radiometric spot-wash assay for squalene synthase. | 1992 | Anal. Biochem. | pmid:1416027 |
| Sun S et al. | The combination effects of phenolic compounds and fluconazole on the formation of ergosterol in Candida albicans determined by high-performance liquid chromatography/tandem mass spectrometry. | 2005 | Anal. Biochem. | pmid:15582556 |