| MeSH term | MeSH ID | Detail |
|---|---|---|
| Occupational Diseases | D009784 | 42 associated lipids |
| Leukemia, Experimental | D007942 | 42 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Nervous System Diseases | D009422 | 37 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Thyroid Neoplasms | D013964 | 33 associated lipids |
| Micronuclei, Chromosome-Defective | D048629 | 33 associated lipids |
| Vitamin E Deficiency | D014811 | 29 associated lipids |
| Brain Diseases | D001927 | 27 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| CAPSTACK E et al. | The biosynthesis of squalene in germinating seeds of Pisum sativum. | 1962 | Biochemistry | pmid:14018475 |
| HORLICK L and AVIGAN J | STEROLS OF SKIN IN THE NORMAL AND TRIPARANOL-TREATED RAT. | 1963 | J. Lipid Res. | pmid:14168146 |
| LUPIEN PJ et al. | EFFECT OF AN ANTIBIOTIC ON LIPID FRACTIONS IN PLASMS AND EGG YOLK OF LAYING HENS. | 1963 | Can J Biochem Physiol | pmid:14083981 |
| GRIESEMER RD and THOMAS RW | LIPOGENESIS IN HUMAN SKIN. II. THE EFFECT OF PHYSICAL AND CHEMICAL FACTORS ON IN VITRO LIPOGENESIS FROM ACETATE. | 1963 | J. Invest. Dermatol. | pmid:14059599 |
| LIBERTI A et al. | ISOTOPIC EFFECTS IN GAS-LIQUID CHROMATOGRAPHY. I. GAS CHROMATOGRAPHIC BEHAVIOUR OF BENZENE AND PERDEUTEROBENZENE. | 1963 | J. Chromatogr. | pmid:14066512 |
| GAYLOR JL | Biosynthesis of skin sterols. III. Conversion of squalene to sterols by rat skin. | 1963 | J. Biol. Chem. | pmid:13946923 |
| GAYLOR JL | Biosynthesis of skin sterols. V. Effect of arsenite inhibition and the accumulation of labeled lanosta-7, 24-dien-3 beta-ol in rat skin. | 1963 | Arch. Biochem. Biophys. | pmid:13946925 |
| JACHYMCZYK W | [Biosynthesis of triterpenoid compounds]. | 1963 | Postepy Biochem. | pmid:13957182 |
| BEELER DA et al. | The biosynthesis of squalene from mevalonic acid-2-C-14 and farnesyl pyrophosphate-4,8,12-C-14 by carrot and tomato enzymes. | 1963 | Arch. Biochem. Biophys. | pmid:13970235 |
| SAMUELSSON B and GOODMAN DS | Stereochemistry of the hydrogen transfer to squalene during its biosynthesis from farnesyl pyrophosphate. | 1963 | Biochem. Biophys. Res. Commun. | pmid:13976173 |