| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hyperlipoproteinemias | D006951 | 15 associated lipids |
| Hyperlipoproteinemia Type III | D006952 | 4 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Influenza, Human | D007251 | 11 associated lipids |
| Keloid | D007627 | 12 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tilvis R et al. | Metabolism of squalene in human fat cells. Demonstration of a two-pool system. | 1982 | J. Biol. Chem. | pmid:7107606 |
| Tiffany JM | Individual variations in human meibomian lipid composition. | 1978 | Exp. Eye Res. | pmid:710541 |
| Torinuki W et al. | Effect of beta-carotene on ultraweak chemiluminescence of UVB-irradiated squalene. | 1982 | Tohoku J. Exp. Med. | pmid:7101278 |
| Richter E and Schäfer SG | The effect of squalane on the absorption of dietary cholesterol by the rat. | 1982 | Res Exp Med (Berl) | pmid:7100640 |
| Richter E and Schäfer SG | Effect of squalane on hexachlorobenzene (HCB) concentrations in tissues of mice. | 1982 | J Environ Sci Health B | pmid:7096897 |
| Messeri G et al. | Amniotic fluid squalene and gestational age. | 1982 | Clin. Chem. | pmid:7094305 |
| Richter E et al. | Effects of dietary paraffin, squalane and sucrose polyester on residue disposition and elimination of hexachlorobenzene in rats. | 1982 | Chem. Biol. Interact. | pmid:7083398 |
| Tilvis RS et al. | Lipid composition of bile and gallbladder mucosa in patients with acalculous cholesterolosis. | 1982 | Gastroenterology | pmid:7060883 |
| Pratt HP | Preimplantation mouse embryos synthesize membrane sterols. | 1982 | Dev. Biol. | pmid:7054002 |
| Bach D and Miller IR | Glyceryl monooleate black lipid membranes obtained from squalene solutions. | 1980 | Biophys. J. | pmid:7053057 |
| Takatsuji H et al. | Formation of dehydrosqualene catalyzed by squalene synthetase in Saccharomyces cerevisiae. | 1982 | J. Biochem. | pmid:7042703 |
| Masuda A et al. | Potentiation of antifungal effect of amphotericin B by squalene, an intermediate for sterol biosynthesis. | 1982 | J. Antibiot. | pmid:7042672 |
| Schroepfer GJ | Sterol biosynthesis. | 1981 | Annu. Rev. Biochem. | pmid:7023367 |
| Yarkoni E and Rapp HJ | Influence of type of oil and surfactant concentration on the efficacy of emulsified Mycobacterium bovis BCG cell walls to induce tumor regression in guinea pigs. | 1980 | Infect. Immun. | pmid:6995325 |
| White SH | Formation of "solvent-free" black lipid bilayer membranes from glyceryl monooleate dispersed in squalene. | 1978 | Biophys. J. | pmid:698340 |
| Torinuki W et al. | [Emission spectral analysis of ultraweak chemiluminescence from linolenic acid and squalene peroxides (author's transl)]. | 1982 | Nihon Hifuka Gakkai Zasshi | pmid:6978954 |
| Yoshino K and Matsuo I | [Squalene peroxide formation by UVA irradiation with or without 8-MOP (author's transl)]. | 1981 | Nihon Hifuka Gakkai Zasshi | pmid:6971356 |
| Jenkins DT et al. | Amniotic fluid squalene: a useful test in prolonged pregnancy. | 1982 | Aust N Z J Obstet Gynaecol | pmid:6959611 |
| Moroyama T | [Sterol metabolism of cultured skin tissue of chick embryo and the effect of anticholesterolemic drugs and chemical carcinogens on it (author's transl)]. | 1981 | Hiroshima Daigaku Shigaku Zasshi | pmid:6953141 |
| Tornabene TG et al. | Phytanyl-glycerol ethers and squalenes in the archaebacterium Methanobacterium thermoautotrophicum. | 1978 | J. Mol. Evol. | pmid:691077 |