| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hyperlipoproteinemias | D006951 | 15 associated lipids |
| Hyperlipoproteinemia Type III | D006952 | 4 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Influenza, Human | D007251 | 11 associated lipids |
| Keloid | D007627 | 12 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| VROMAN HE and BAKER GL | LIMITS OF DETECTION OF SOME LIPIDS IN THIN-LAYER CHROMATOGRAPHY. | 1965 | J. Chromatogr. | pmid:14334204 |
| GOSSELIN L and DUVIVIER J | [BIOSYNTHESIS OF FARNESOL PYROPHOSPHATE AND SQUALENE FROM 2-C14-MEVALONIC ACID BY CELL FRACTIONS OF ADRENAL HOMOGENATE]. | 1965 | Bull. Soc. Chim. Biol. | pmid:14337120 |
| GOODWIN TW and WILLIAMS RJ | A MECHANISM FOR THE CYCLIZATION OF AN ACYCLIC PRECURSOR TO FORM BETA-CAROTENE. | 1965 | Biochem. J. | pmid:14342248 |
| Puhvel SM and Sakamoto M | An in vivo evaluation of the inflammatory effect of purified comedonal components in human skin. | 1977 | J. Invest. Dermatol. | pmid:143497 |
| NICOLAIDES N and ROTHMAN S | The site of sterol and squalene synthesis in the human skin. | 1955 | J. Invest. Dermatol. | pmid:14354270 |
| BOUGHTON B et al. | Some observations of the nature, origin and possible function of the squalene and other hydrocarbons of human sebum. | 1955 | J. Invest. Dermatol. | pmid:14354278 |
| MACKENNA RM et al. | Squalene and other hydrocarbons in human sebum. | 1955 | J. Physiol. (Lond.) | pmid:14354699 |
| Allison AC and Byars NE | Syntex adjuvant formulation. | 1992 | Res. Immunol. | pmid:1439132 |
| SCHOEN H and FAHSOLD W | [Studies on the problem of resorption of squalene]. | 1960 | Klin. Wochenschr. | pmid:14443328 |
| Boutaud O et al. | Preferential cyclization of 2,3(S):22(S),23-dioxidosqualene by mammalian 2,3-oxidosqualene-lanosterol cyclase. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1445330 |
| POPJAK G et al. | Studies on the biosynthesis of cholesterol. XVI. Chemical synthesis of 1-H2-3-2-C-14- and 1-D2-2-C-14-trans-trans-farnesyl pyrophosphate and their utilization in squalene biosynthesis. | 1962 | J. Biol. Chem. | pmid:14487886 |
| POPJAK G et al. | Sterospecificity of hydrogen transfer from reduced triphosphopyridine nucleotide to squalene during its synthesis from farnesyl pyrophosphate. | 1962 | Biochem. Biophys. Res. Commun. | pmid:14487887 |
| ROTHBLAT GH et al. | A quantitative colorimetric assay for squalene. | 1962 | Anal. Biochem. | pmid:14494417 |
| Veen M et al. | Combined overexpression of genes of the ergosterol biosynthetic pathway leads to accumulation of sterols in Saccharomyces cerevisiae. | 2003 | FEMS Yeast Res. | pmid:14554200 |
| Rajamani R and Gao J | Balancing kinetic and thermodynamic control: the mechanism of carbocation cyclization by squalene cyclase. | 2003 | J. Am. Chem. Soc. | pmid:14558824 |
| Saint-Léger D | [Normal and pathologic sebaceous function. Research in a shallow milieu?]. | 2003 | Pathol. Biol. | pmid:14567194 |
| Das B et al. | In vitro cytoprotective activity of squalene on a bone marrow versus neuroblastoma model of cisplatin-induced toxicity. implications in cancer chemotherapy. | 2003 | Eur. J. Cancer | pmid:14602142 |
| Mateos R et al. | Antioxidant effect of phenolic compounds, alpha-tocopherol, and other minor components in virgin olive oil. | 2003 | J. Agric. Food Chem. | pmid:14611189 |
| Miettinen TA and Gylling H | Synthesis and absorption markers of cholesterol in serum and lipoproteins during a large dose of statin treatment. | 2003 | Eur. J. Clin. Invest. | pmid:14636301 |
| He HP et al. | Supercritical carbon dioxide extraction of oil and squalene from amaranthus grain. | 2003 | J. Agric. Food Chem. | pmid:14690374 |